scholarly journals Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding

2015 ◽  
Vol 51 (38) ◽  
pp. 8130-8133 ◽  
Author(s):  
Gemma A. Bullen ◽  
James H. R. Tucker ◽  
Anna F. A. Peacock
Keyword(s):  
Dna Binding ◽  
Biomolecular Recognition ◽  
Selective Dna Binding

Here we detail the first example of anthracene photodimerisation in peptides, and use it to trigger a selective biomolecular recognition event.

scholarly journals The molecular basis of selective DNA binding by the BRG1 AT-hook and bromodomain

2020 ◽  
Vol 1863 (8) ◽  
pp. 194566
Author(s):  
Julio C. Sanchez ◽  
Liyang Zhang ◽  
Stefania Evoli ◽  
Nicholas J. Schnicker ◽  
Maria Nunez-Hernandez ◽  
...  
Keyword(s):  
Dna Binding ◽  
Molecular Basis ◽  
Selective Dna Binding

scholarly journals Site-Selective DNA Binding Drugs

2003 ◽  
Vol 10 (10) ◽  
pp. 895-897 ◽  
Author(s):  
Scot W. Ebbinghaus
Keyword(s):  
Dna Binding ◽  
Selective Dna Binding ◽  
Site Selective

scholarly journals Correction to Metal-Based Netropsin Mimics Showing AT-Selective DNA Binding and DNA Cleavage Activity at Red Light

2019 ◽  
Vol 58 (14) ◽  
pp. 9514-9514
Author(s):  
Ashis K. Patra ◽  
Tuhin Bhowmick ◽  
Suryanarayanarao Ramakumar ◽  
Akhil R. Chakravarty
Keyword(s):  
Dna Binding ◽  
Dna Cleavage ◽  
Red Light ◽  
Cleavage Activity ◽  
Dna Cleavage Activity ◽  
Selective Dna Binding

scholarly journals Dynamic and selective DNA-binding activity of Smc5, a core component of the Smc5-Smc6 complex

Cell Cycle ◽  
2011 ◽  
Vol 10 (4) ◽  
pp. 690-700 ◽  
Author(s):  
Marc-André Roy ◽  
Nadeem Siddiqui ◽  
Damien D'Amours
Keyword(s):  
Dna Binding ◽  
Binding Activity ◽  
Core Component ◽  
Dna Binding Activity ◽  
Selective Dna Binding

scholarly journals Sequence-selective DNA binding with cell-permeable oligoguanidinium–peptide conjugates

2015 ◽  
Vol 51 (23) ◽  
pp. 4811-4814 ◽  
Author(s):  
Jesús Mosquera ◽  
Mateo I. Sánchez ◽  
Julián Valero ◽  
Javier de Mendoza ◽  
M. Eugenio Vázquez ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Site ◽  
Peptide Binding ◽  
Peptide Fragment ◽  
Peptide Conjugates ◽  
Bzip Protein ◽  
Short Peptide ◽  
Peptide Binding Site ◽  
Selective Dna Binding

Conjugation of a short peptide fragment from a bZIP protein to an oligoguanidinium tail results in a DNA-binding miniprotein that selectively interacts with composite sequences containing the peptide-binding site next to an A/T-rich tract.

scholarly journals High-affinity sequence-selective DNA binding by iridium(iii) polypyridyl organometallopeptides

2016 ◽  
Vol 52 (6) ◽  
pp. 1234-1237 ◽  
Author(s):  
Ilaria Gamba ◽  
Iria Salvadó ◽  
Rosa F. Brissos ◽  
Patrick Gamez ◽  
José Brea ◽  
...  
Keyword(s):  
Dna Binding ◽  
Cell Lines ◽  
Peptide Synthesis ◽  
Cytotoxic Effect ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis ◽  
Synthesis Methods ◽  
High Affinity ◽  
Dna Binding Affinity ◽  
Selective Dna Binding

We demonstrate the application of solid-phase peptide synthesis methods for assembling polynuclear Ir(iii) organometallopeptides that exhibit high DNA-binding affinity, sequence selectivity, and high cytotoxic effect towards a set of cancer cell lines.

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