Egg-shell derived carbon dots for base pair selective DNA binding and recognition

Here, we have used food waste derived chicken egg shell membrane as a cost effective carbon source for the synthesis of heteroatom doped fluorescent carbon dots. We are able to apply these synthesized carbon dots as a new fluorescent probe for label free base pair selective and sequence specific double stranded DNA binding.

High-affinity sequence-selective DNA binding by iridium(iii) polypyridyl organometallopeptides

We demonstrate the application of solid-phase peptide synthesis methods for assembling polynuclear Ir(iii) organometallopeptides that exhibit high DNA-binding affinity, sequence selectivity, and high cytotoxic effect towards a set of cancer cell lines.

Exploiting anthracene photodimerization within peptides: light induced sequence-selective DNA binding

Here we detail the first example of anthracene photodimerisation in peptides, and use it to trigger a selective biomolecular recognition event.

Sequence-selective DNA binding with cell-permeable oligoguanidinium–peptide conjugates

Conjugation of a short peptide fragment from a bZIP protein to an oligoguanidinium tail results in a DNA-binding miniprotein that selectively interacts with composite sequences containing the peptide-binding site next to an A/T-rich tract.