Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis

Mitchell Hattie; Tasuku Ito; Aleksandra W. Debowski; Takatoshi Arakawa; Takane Katayama; Kenji Yamamoto; Shinya Fushinobu; Keith A. Stubbs

doi:10.1039/c5cc05494j

Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis

Chemical Communications ◽

10.1039/c5cc05494j ◽

2015 ◽

Vol 51 (81) ◽

pp. 15008-15011 ◽

Cited By ~ 8

Author(s):

Mitchell Hattie ◽

Tasuku Ito ◽

Aleksandra W. Debowski ◽

Takatoshi Arakawa ◽

Takane Katayama ◽

...

Keyword(s):

Structural Analysis ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Insight Into ◽

Gaining Insight

Synthesis and structural analysis of rationally developed inhibitors.

Insight into mechanism of small molecule inhibitors of the MDM2–p53 interaction: Molecular dynamics simulation and free energy analysis

Journal of Molecular Graphics and Modelling ◽

10.1016/j.jmgm.2011.06.003 ◽

2011 ◽

Vol 30 ◽

pp. 46-53 ◽

Cited By ~ 28

Author(s):

Jianzhong Chen ◽

Jinan Wang ◽

Beisi Xu ◽

Weiliang Zhu ◽

Guohui Li

Keyword(s):

Molecular Dynamics ◽

Free Energy ◽

Molecular Dynamics Simulation ◽

Small Molecule ◽

Energy Analysis ◽

Small Molecule Inhibitors ◽

Dynamics Simulation ◽

Free Energy Analysis ◽

Insight Into

Gaining Insight Into Weight Loss and Gain Patterns

PsycTHERAPY Dataset ◽

10.1037/v00013-001 ◽

2002 ◽

Author(s):

Ann Mary Kearney-Cooke

Keyword(s):

Weight Loss ◽

Insight Into ◽

Gaining Insight

From molecular diagnostics to molecular targeted therapy with natural product small molecule inhibitors in oral squamous cell carcinoma

Planta Medica ◽

10.1055/s-2007-986722 ◽

2007 ◽

Vol 73 (09) ◽

Cited By ~ 1

Author(s):

VB Konkimalla ◽

VL Suhas ◽

NR Chandra ◽

E Gebhart ◽

T Efferth

Keyword(s):

Squamous Cell Carcinoma ◽

Targeted Therapy ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Natural Product ◽

Molecular Diagnostics ◽

Small Molecule ◽

Squamous Cell ◽

Molecular Targeted Therapy ◽

Small Molecule Inhibitors

Structural analysis of SRPN6 provides insight into its anti-Plasmodial function

10.1603/ice.2016.105544 ◽

2016 ◽

Author(s):

David Meekins

Keyword(s):

Structural Analysis ◽

Insight Into

Scope on the Skies: Gaining Insight Into Mars

Science Scope ◽

10.2505/4/ss18_041_08_78 ◽

2018 ◽

Vol 041 (08) ◽

Author(s):

Bob Riddle

Keyword(s):

Insight Into ◽

Gaining Insight

Faculty Opinions recommendation of Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004750.54854 ◽

2002 ◽

Author(s):

Carol Otey

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors

Faculty Opinions recommendation of Identification of small molecule inhibitors of anthrax lethal factor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1016978.201559 ◽

2004 ◽

Author(s):

Kristina Downing

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Lethal Factor ◽

Anthrax Lethal Factor

Faculty Opinions recommendation of Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017973.285766 ◽

2005 ◽

Author(s):

George Perry

Keyword(s):

Small Molecule ◽

Amyloid Beta ◽

Small Molecule Inhibitors

Faculty Opinions recommendation of High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023153.264839 ◽

2005 ◽

Author(s):

Robert Kelley

Keyword(s):

T Cell ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

High Affinity

Faculty Opinions recommendation of Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1024840.292879 ◽

2005 ◽

Author(s):

Chandra Kumar

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Phosphoinositide Dependent Kinase