Chiral liquid membrane for enantioselective separation of racemic ibuprofen by l-tartaric acid derivatives

Use of a chiral liquid membrane is an attractive separation method for racemic ibuprofen, and the separation factor could be up to 1.38 under optimal experimental conditions.

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Enantioselective Liquid–Liquid Extraction of Racemic Ibuprofen by l-Tartaric Acid Derivatives

Journal of Chemical & Engineering Data ◽

10.1021/je500292c ◽

2014 ◽

Vol 59 (8) ◽

pp. 2517-2522 ◽

Cited By ~ 12

Author(s):

Zhongqi Ren ◽

Yong Zeng ◽

Yutao Hua ◽

Yongqi Cheng ◽

Zhimin Guo

Keyword(s):

Tartaric Acid ◽

Liquid Extraction ◽

Tartaric Acid Derivatives ◽

Liquid Liquid Extraction ◽

Racemic Ibuprofen

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Separation of Cd(II) and Ni(II) ions by supported liquid membrane using D2EHPA/M2EHPA as mobile carrier

Chemical Papers ◽

10.2478/s11696-013-0506-6 ◽

2014 ◽

Vol 68 (6) ◽

Cited By ~ 9

Author(s):

Roghaye Mahmoodi ◽

Toraj Mohammadi ◽

Mansoor Moghadam

Keyword(s):

Carrier Concentration ◽

Separation Factor ◽

Liquid Membrane ◽

Supported Liquid Membrane ◽

Feed Concentration ◽

Experimental Conditions ◽

Ptfe Film ◽

Mobile Carrier ◽

Maximum Value ◽

Separation Factors

AbstractThe separation of Cd(II) and Ni(II) ions was studied in an aqueous sulphate medium using supported liquid membrane (SLM). D2EHPA/M2EHPA was used as a mobile carrier, microporous hydrophobic PTFE film was used as a solid support for the liquid membrane, and the strip phase was sulphuric acid. The effects of different parameters such as feed concentration, carrier concentration, feed phase pH, and strip phase pH on the separation factor and flux of Cd(II) and Ni(II) ions were studied. The optimum values obtained to achieve the maximum flux were 5.0 for feed pH, 40 vol. % for D2EHPA/M2EHPA concentration in the membrane phase, 0.5 for strip pH, and 0.012 mass % for feed concentration. Under these optimum conditions, the flux values of Cd(II) and Ni(II) were 15.7 × 10−7 kg m−2 s−1 and 2.6 × 10−7 kg m−2 s−1, respectively. The separation factors of Cd(II) over Ni(II) were studied under different experimental conditions. At a carrier concentration of 10 vol. % and feed concentration of 0.012 mass %, the maximum value of 185.1 was obtained for the separation factor of Cd(II) over Ni(II). After 24 h, the percentages of the extracted Cd(II) and Ni(II) were 83.3 % and 0.45 %, respectively.

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Biphasic Enantioselective Partitioning of R,S-Omeprazole Enantiomers Using Chiral Extraction

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.1030-1032.2334 ◽

2014 ◽

Vol 1030-1032 ◽

pp. 2334-2339

Author(s):

Yan Liang Li ◽

Zhong Zhen Liu ◽

Yu Fen Huang ◽

Lan Wei ◽

Lian Xi Huang ◽

...

Keyword(s):

Tartaric Acid ◽

Organic Phase ◽

Separation Factor ◽

Extraction Efficiency ◽

Distribution Coefficients ◽

Variable Parameters ◽

Chiral Selectors ◽

Tartaric Acid Derivatives ◽

Hexyl Ester ◽

Chiral Extraction

Enantioselective partitioning of racemic omeprazole enantiomers was studied using a biphasic recognition chiral extraction system. Hydrophilic hydroxypropyl-ڂ-cyclodextrin in aqueous phase and hydrophobic D-tartaric acid hexyl ester in organic phase as chiral selectors which preferentially recognize (R)-omeprazole enantiomer and (S)-omeprazole enantiomer, respectively. Different experimental variable parameters could affect the chiral extraction efficiency. The largest distribution coefficientskS,kRand separation factorځwere obtained at concentrations o f 0.1 mol/L HP-ڂ-CD and 0.2 mol/L D-tartaric acid hexyl ester, which were 47.38, 58.65 and 1.24, respectively.kRis always larger thankSwhen using different kinds of tartaric acid derivatives as chiral selectors in organic phase. The present study also reveal the mechanism of biphasic recognition chiral extraction forR,S-omeprazole enantiomers.

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Synthesis of optically active macrolides with hydrazide fragments from tetrahydropyran and L-(+)-tartaric acid derivatives

Chemistry of Natural Compounds ◽

10.1007/s10600-013-0708-8 ◽

2013 ◽

Vol 49 (4) ◽

pp. 691-693 ◽

Cited By ~ 4

Author(s):

G. Yu. Ishmuratov ◽

M. P. Yakovleva ◽

G. R. Mingaleeva ◽

M. A. Shutova ◽

R. R. Muslukhov ◽

...

Keyword(s):

Tartaric Acid ◽

Optically Active ◽

Tartaric Acid Derivatives

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The Effect of Experimental Conditions on Methane (95%)–Propane (5%) Hydrate Formation

Energies ◽

10.3390/en13246710 ◽

2020 ◽

Vol 13 (24) ◽

pp. 6710

Author(s):

Sotirios Nik. Longinos ◽

Mahmut Parlaktuna

Keyword(s):

Power Consumption ◽

Separation Factor ◽

Induction Time ◽

Hydrate Formation ◽

Equilibrium Line ◽

General View ◽

Experimental Conditions ◽

Rushton Turbine ◽

Pitched Blade Turbine

In the present study, the effect of different kinds of impellers with different baffles or no baffle was investigated. Up-pumping pitched blade turbine (PBTU) and Rushton turbine (RT) were the two types of impellers tested. The reactor was equipped with different designs of baffles: full, half and surface baffles or no baffles. Single (PBTU or RT) and dual (PBTU/PBTU or RT/RT) use of impellers with full (FB), half (HB), surface (SB) and no baffle (NB) combinations formed two sets of 16 experiments. There was estimation of rate of hydrate formation, induction time, hydrate productivity, overall power consumption, split fraction and separation factor. In both single and dual impellers, the results showed that RT experiments are better compared to PBTU in rate of hydrate formation. The induction time is almost the same since we are deep in the equilibrium line while hydrate productivity values are higher in PBTU compared to RT experiments. As general view RT experiments consume more energy compared to PBTU experiments.

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Separation of Free and Protein-Bound Ligand Molecules by Means of Protein-Coated Charcoal

Clinical Chemistry ◽

10.1093/clinchem/20.9.1146 ◽

1974 ◽

Vol 20 (9) ◽

pp. 1146-1149 ◽

Cited By ~ 2

Author(s):

Esper Mortensen

Keyword(s):

Separation Method ◽

Mass Action ◽

Careful Evaluation ◽

Experimental Conditions ◽

Model Experiments

Abstract Separation of free and protein-bound ligand molecules by means of protein-coated charcoal has been studied in model experiments. The results can be described by applying the simple laws of mass action and dilution, and indicate the need for a careful evaluation of the charcoal that is being used and a testing against an ideal separation method whenever experimental conditions are determined or changed.

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Pertraction of methylene blue using a mixture of D2EHPA/M2EHPA and sesame oil as a liquid membrane

Chemical Papers ◽

10.2478/s11696-013-0374-0 ◽

2013 ◽

Vol 67 (7) ◽

Cited By ~ 21

Author(s):

Pezhman Kazemi ◽

Mohammad Peydayesh ◽

Alireza Bandegi ◽

Toraj Mohammadi ◽

Omid Bakhtiari

Keyword(s):

Methylene Blue ◽

Phosphoric Acid ◽

Liquid Membrane ◽

Membrane Surface ◽

Sesame Oil ◽

Acetic Acid Concentration ◽

Membrane Phase ◽

Experimental Conditions ◽

Feed Phase ◽

Kinetics Of

AbstractAn experimental study on the pertraction of methylene blue (MB) through a supported liquid membrane (SLM) using a mixture of mono-(2-etylhexyl) ester of phosphoric acid (M2EHPA) and bis-(2-etylhexyl) ester of phosphoric acid (D2EHPA) and sesame oil as the liquid membrane (LM) was performed. Parameters affecting the pertraction of MB such as initial MB concentration, carrier concentration, feed phase pH, and stripping phase concentration were analyzed. Optimal experimental conditions for MB pertraction (permeability of 5.63 × 10−6) were obtained after a 7 h separation with the MB concentration in the feed phase of 80 mg L−1, D2EHPA/M2EHPA concentration in membrane phase of 40 vol. %, feed pH of 6, and acetic acid concentration in the stripping phase of 0.4 mol L−1. Kinetics of transport and stability of the SLM system were also studied and the mass transfer coefficient for this system was evaluated. Scanning electron microscopy (SEM) was used to morphologically characterize the membrane surface.

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