Design, synthesis and biological evaluation of novel unsymmetrical azines as quorum sensing inhibitors

RSC Advances ◽  
2015 ◽  
Vol 5 (97) ◽  
pp. 80027-80038 ◽  
Author(s):  
Sumit S. Chourasiya ◽  
Deepika Kathuria ◽  
Shaminder Singh ◽  
Vijay C. Sonawane ◽  
Asit K. Chakraborti ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Biological Evaluation ◽  
One Pot ◽  
Design Synthesis ◽  
Quorum Sensing Inhibitors ◽  
Synthesis And Biological Evaluation

In this report, novel unsymmetrical azines have been designed and synthesised by using one pot approach. Further, they were evaluated as quorum sensing inhibitors.

Design, Synthesis and Biological Evaluation of Triazole-Containing 2-Phenylindole and Salicylic Acid as Quorum Sensing Inhibitors Against Pseudomonas aeruginosa

2018 ◽  
Vol 3 (32) ◽  
pp. 9170-9180 ◽  
Author(s):  
Singireddi Srinivasarao ◽  
Shashidhar Nizalapur ◽  
Tsz Tin Yu ◽  
Daniel Stanley Wenholz ◽  
Prakruti Trivedi ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Salicylic Acid ◽  
Quorum Sensing ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Quorum Sensing Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimidazoles as novel inhibitors of LasR dependent quorum sensing in Pseudomonas aeruginosa

RSC Advances ◽  
2019 ◽  
Vol 9 (50) ◽  
pp. 29273-29292 ◽  
Author(s):  
Singireddi Srinivasarao ◽  
Adinarayana Nandikolla ◽  
Shashidhar Nizalapur ◽  
Tsz Tin Yu ◽  
Sravani Pulya ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Quorum Sensing ◽  
Cell Line ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Hek 293 ◽  
Line P ◽  
Synthesis And Biological Evaluation ◽  
Hek 293 Cell Line

Out of 40 benzimdazoles, 12 exhibited potent QSI activity against P. aeruginosa6p, most active QSI is docked to LasR and is less toxic against HEK 293 cell line.

Design, synthesis, biological evaluation and toxicity studies of N,N-disubstituted biguanides as quorum sensing inhibitors

2014 ◽  
Vol 24 (5) ◽  
pp. 1974-1987 ◽  
Author(s):  
Shaminder Singh ◽  
Pravin J. Wanjari ◽  
Sonam Bhatia ◽  
Vijay C. Sonwane ◽  
Asit K. Chakraborti ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Toxicity Studies ◽  
Quorum Sensing Inhibitors

scholarly journals Synthesis and Biological Evaluation of Azamacrolide Comprising the Triazole Moiety as Quorum Sensing Inhibitors

Molecules ◽  
2018 ◽  
Vol 23 (5) ◽  
pp. 1086 ◽  
Author(s):  
Bin Zhang ◽  
Bingyi Guo ◽  
Yunlong Bai ◽  
Huizhe Lu ◽  
Yanhong Dong
Keyword(s):  
Quorum Sensing ◽  
Biological Evaluation ◽  
Quorum Sensing Inhibitors ◽  
Synthesis And Biological Evaluation
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