Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimidazoles as novel inhibitors of LasR dependent quorum sensing in Pseudomonas aeruginosa
Out of 40 benzimdazoles, 12 exhibited potent QSI activity against P. aeruginosa6p, most active QSI is docked to LasR and is less toxic against HEK 293 cell line.
2012 ◽
Vol 10
(30)
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pp. 6032
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2020 ◽
Vol 194
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pp. 112252
2011 ◽
Vol 21
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pp. 1156-1165
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2018 ◽
Vol 158
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pp. 753-766
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2011 ◽
Vol 19
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pp. 4812-4819
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2019 ◽
Vol 67
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pp. 1088-1098
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