EFECTO DE LA SUPLEMENTACIÓN ENZIMÁTICA EN PARÁMETROS PRODUCTIVOS DE CUYES (LÍNEA SINTÉTICA P 0.625)

The aim of this study was to evaluate the effect of the supplementation of an enzymatic complex in integral diets for guinea pigs in the growing phase on productive performance. In total, 54 male guinea pigs (Synthetic line P 0.625) were used and submitted to a diet free of the enzyme complex (T1), and two experimental ones, one with 0.1% (T2) and the other with 0.2% (T3) of enzyme complex evaluated between two weeks of age (weaning) and after rearing (nine weeks old). It was statically evaluated and there were found no significant difference between treatments in relation to final body weight, weight gain, feed intake and feed conversion; and it was reported the weekly average of percentage of dairy dry matter intake by body weight.

Impact of Gait and Diameter during Circular Exercise on Front Hoof Area, Vertical Force, and Pressure in Mature Horses

Circular exercise can be used at varying gaits and diameters to exercise horses, with repeated use anecdotally relating to increased lameness. This work sought to characterize mean area, mean vertical force, and mean pressure of the front hooves while exercising in a straight line at the walk and trot, and small (10-m diameter) and large circles (15-m diameter) at the walk, trot, and canter. Nine mature horses wore TekscanTM Hoof Sensors on their forelimbs adhered with a glue-on shoe. Statistical analysis was performed in SAS 9.4 with fixed effects of leg, gait, and exercise type (PROC GLIMMIX) and p < 0.05 as significant. For all exercise types, the walk had greater mean pressure than the trot (p < 0.01). At the walk, the straight line had greater mean area loaded than the large circle (p = 0.01), and both circle sizes had lower mean vertical force than the straight line (p = 0.003). During circular exercise at the canter, the outside front limb had greater mean area loaded than at the walk and trot (p = 0.001). This study found that gait is an important factor when evaluating circular exercise and should be considered when exercising horses to prevent injury.

Nan King’s Orientation in Sarah Waters’s Tipping the Velvet: A Journey of Gender and Sexual Self-Discovery Following “The Slantwise Direction of Queer Desire”

In Tipping the Velvet (1998), Sarah Waters explores the notion of “gender performativity” as studied by Judith Butler (1990, 1993). Its protagonist, Nancy Astley, becomes aware of her sexuality and comes up with doubts about her gender as responding to the stable label society has put on her. This naïve girl moves from performing gender on stage to cross-dressing off-stage amid the crowds of London, not following, as Sarah Ahmed (2006) puts it, “the straight line” (p. 70). The aim of this paper is to explain how this straightness – both in terms of direction and heterosexuality – is the term Nancy, later on renamed Nan King, does not feel comfortable with. Throughout the novel, Nan’s discovery of a whole world of sexual and identity possibilities leads her to look for her own orientation, as her position in relation to the rest of “objects” around her is a queer one.

Dynamin conditional knockout fibroblasts: Tamoxifen inducible Knockout method v1

This cell line was described and characterized in the following paper: Ferguson, S.M., Raimondi, A., Paradise, S., Shen, H., Mesaki, K., Ferguson, A., Destaing, O., Ko, G., Takasaki, J., Cremona, O., O’Toole, E., De Camilli P. Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Developmental Cell 17, 811-822, 2009. PMID: 20059951]. This procedure describes tamoxifeninducible KO method using this cell line.

Lost Identities

Extending the implications of this turn from fleshed-out character, chapter four highlights the genre’s later focus on identities lost altogether (if only apparently). Among more recent authors, some have collapsed the mysteries earlier involving dead victims with those now entangling the unknown investigator himself. After all, the detective’s presence has always verged on a condition of invisibility, which has gradually become an informing premise within the genre. Central figures more than occasionally seem unaware of their tormented pasts, or even of their own present insights and skills. Alternatively, those who are so aware now strive to protect their identities by staying off the grid, avoiding scrutiny altogether, including the reader’s inquiring eye. Remaining invisible becomes either a chronic, unbidden condition or an increasingly hard act to sustain, with concealment having become the genre’s signature narrative line.

Drawing the Line

What should we do, think, and feel when artists whom we love do terrible things? Recent years have been punctuated by revelations and reminders that popular artists (musicians, directors, actors, comedians, painters) have committed a range of morally condemnable acts. How should we respond to the immorality of great artists? Does it affect the aesthetic quality of the work these artists have produced? Is it morally permissible for us to engage with or enjoy that work? Should such work even be available for consumption, or should it be “canceled”? In short, can we separate the art from the artist? Drawing the Line argues that it doesn’t matter whether we can separate the art from the artist, because we shouldn’t. Taking both art and morality seriously requires grappling with them together. Recognizing the moral and aesthetic relationships between art and artist is essential to determining when and where we should draw the line when good artists do bad things.

A mini-module with embedded spacers for high-throughput ultrafiltration

Ultrafiltration membrane modules suffer from performance losses that arise during filtration from concentration polarization and fouling. Such performance losses are frequently mitigated by controlling the hydrodynamic conditions at the membrane/fluid interface. For instance, the hydrodynamic conditions are manipulated using mesh spacers that act as a static mixer. The design of such spacers is rarely optimized to effectively maintain mass transport through the membrane. Also, the spacer is an additional part added to the feed channel of the membrane module, improving mass transport in general, yet accepting less transport in dead zones.Here, we present a mini module with spacers embedded in the module housing of a flat-sheet ultrafiltration membrane to attain high permeation rates. The performance of two new embedded spacer geometries – staggered herringbone and sinusoidal corrugation – prove experimentally that indeed a CFD-simulated flux increase can be realized during bovine serum albumin (BSA) filtration. The flow characteristics inside the mini module are further investigated using magnetic resonance velocity imaging. The new embedded sinusoidal corrugation spacers outper- form conventional mesh spacer inlays. The fabrication of such module-embedded spacers has been conceptually implemented through an in-silico design and a 3D-printing production process. The latter can be easily realized using injection molding processes, as is now done for the Sartorius ambra(R) crossflow product line.

Mathematical modeling of the axial-piston pump power regulator

A mathematical model of the regulator was developed; a scheme for its solution in the Matlab-Simulink environment was suggested; dependencies of the spool movement (x1), piston (x2), transition time (t) and other parameters on the pressure in the pressure line (p) have been determined. The mathematical model of the regulator establishes the effect of pressure on control process parameters. When the pressure increases from 30 to 45 MPa, the regulator spool moves at a distance varying from 0.4 - 2.8 mm. The spool movement is proportional to the pressure. The piston movement is more sensitive to the change in pressure. It changes within the range of 3–19 mm, while the relationship is non-linear. The cylidner pressure and the ratio of rocker arms are proportional to the pressure and increases 1.5 times; the transition time is expressed by a non-linear dependence and decreases two-fold.

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A randomized split mouth clinical trial of the application of the desensitizer agents for tooth sensitivity

Background: Dentin hypersensitivity (DH) affects 3%-75% of the people and is one of the morbid tooth conditions. Hence in the present study we aim to examine the clinical effectiveness of 3 different desensitizing agents in decreasing pain of DH in time of 1 month.Methods: Fifty subjects with cervical DH in at least one tooth in any three of the 4 quadrants were selected. VAS was used to note the pain. Each quadrant in an individual was randomly assigned. Profluorid varnish, Admira protect, and PRG‑Barrier coat was used. VAS scores for the tactile and air stimuli were noted immediately after application, 1 week, and after 1 month. The data was analyzed keeping p<0.05 as significant.Results: VAS significantly reduced for all three groups from the base line (p<0.001). Admira protect showed significant reduction of hypersensitivity scores at 1 month compared to other groups (p<0.001).Conclusions: Admira protect was better at lowering the pain due to DH than PRG‑barrier coat and Profluorid varnish after 1 month of application.