scholarly journals A first-in-class and a fished out anticancer platinum compound: cis-[PtCl2(NH3)2] and cis-[PtI2(NH3)2] compared for their reactivity towards DNA model systems

2016 ◽  
Vol 45 (20) ◽  
pp. 8587-8600 ◽  
Author(s):  
Domenica Musumeci ◽  
Chiara Platella ◽  
Claudia Riccardi ◽  
Antonello Merlino ◽  
Tiziano Marzo ◽  
...  

The reactivity of cis-PtI2(NH3)2 with selected DNA model systems, in single, double strand or G-quadruplex form, has been studied by circular dichroism, UV-visible spectroscopy and electrospray mass spectrometry using cisplatin as a control.

2010 ◽  
Vol 132 (27) ◽  
pp. 9328-9334 ◽  
Author(s):  
Gavin W. Collie ◽  
Gary N. Parkinson ◽  
Stephen Neidle ◽  
Frédéric Rosu ◽  
Edwin De Pauw ◽  
...  

2020 ◽  
Vol 56 (62) ◽  
pp. 8814-8817 ◽  
Author(s):  
Monika Kijewska ◽  
Angelika Czerwińska ◽  
Samah Al-Harthi ◽  
Grzegorz Wołczański ◽  
Mateusz Waliczek ◽  
...  

The intramolecular interactions between the fructosyl moiety and phenylboronic acid incorporated into various positions of the peptide chain were investigated using mass spectrometry (MS), circular dichroism (CD), and nuclear magnetic resonance (NMR).


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