scholarly journals Electrospray Mass Spectrometry of Telomeric RNA (TERRA) Reveals the Formation of Stable Multimeric G-Quadruplex Structures

2010 ◽  
Vol 132 (27) ◽  
pp. 9328-9334 ◽  
Author(s):  
Gavin W. Collie ◽  
Gary N. Parkinson ◽  
Stephen Neidle ◽  
Frédéric Rosu ◽  
Edwin De Pauw ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
G Quadruplex ◽  
Telomeric Rna

scholarly journals Tetramolecular G-quadruplex formation pathways studied by electrospray mass spectrometry

2010 ◽  
Vol 38 (15) ◽  
pp. 5217-5225 ◽  
Author(s):  
F. Rosu ◽  
V. Gabelica ◽  
H. Poncelet ◽  
E. De Pauw
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
G Quadruplex ◽  
Quadruplex Formation

scholarly journals A first-in-class and a fished out anticancer platinum compound: cis-[PtCl2(NH3)2] and cis-[PtI2(NH3)2] compared for their reactivity towards DNA model systems

2016 ◽  
Vol 45 (20) ◽  
pp. 8587-8600 ◽  
Author(s):  
Domenica Musumeci ◽  
Chiara Platella ◽  
Claudia Riccardi ◽  
Antonello Merlino ◽  
Tiziano Marzo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Circular Dichroism ◽  
Electrospray Mass Spectrometry ◽  
Model Systems ◽  
Platinum Compound ◽  
Visible Spectroscopy ◽  
G Quadruplex ◽  
Uv Visible ◽  
Circular Dichroïsm

The reactivity of cis-PtI2(NH3)2 with selected DNA model systems, in single, double strand or G-quadruplex form, has been studied by circular dichroism, UV-visible spectroscopy and electrospray mass spectrometry using cisplatin as a control.

scholarly journals Hybridization of short complementary PNAs to G-quadruplex forming oligonucleotides: An electrospray mass spectrometry study

Biopolymers ◽  
2009 ◽  
Vol 91 (4) ◽  
pp. 244-255 ◽  
Author(s):  
Jussara Amato ◽  
Giorgia Oliviero ◽  
Edwin De Pauw ◽  
Valérie Gabelica
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
Mass Spectrometry Study ◽  
G Quadruplex

Analysis of Trace Level Perchlorate in Drinking Water and Ground Water by Electrospray Mass Spectrometry

1998 ◽  
Author(s):  
Rebecca A. Clewell ◽  
Wayne T. Brashear ◽  
David T. Tsui ◽  
Sanwat Chaudhuri ◽  
Rachel S. Cassady
Keyword(s):  
Mass Spectrometry ◽  
Drinking Water ◽  
Ground Water ◽  
Electrospray Mass Spectrometry ◽  
Trace Level

scholarly journals DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions

2021 ◽  
Author(s):  
Anirban Ghosh ◽  
Eric Largy ◽  
Valérie Gabelica
Keyword(s):  
Mass Spectrometry ◽  
Drug Targets ◽  
Native Mass Spectrometry ◽  
Drug Binding ◽  
Quadruplex Dna ◽  
Dna Structures ◽  
Nmr Structures ◽  
G Quadruplex ◽  
Screening Assays

Abstract G-quadruplex DNA structures have become attractive drug targets, and native mass spectrometry can provide detailed characterization of drug binding stoichiometry and affinity, potentially at high throughput. However, the G-quadruplex DNA polymorphism poses problems for interpreting ligand screening assays. In order to establish standardized MS-based screening assays, we studied 28 sequences with documented NMR structures in (usually ∼100 mM) potassium, and report here their circular dichroism (CD), melting temperature (Tm), NMR spectra and electrospray mass spectra in 1 mM KCl/100 mM trimethylammonium acetate. Based on these results, we make a short-list of sequences that adopt the same structure in the MS assay as reported by NMR, and provide recommendations on using them for MS-based assays. We also built an R-based open-source application to build and consult a database, wherein further sequences can be incorporated in the future. The application handles automatically most of the data processing, and allows generating custom figures and reports. The database is included in the g4dbr package (https://github.com/EricLarG4/g4dbr) and can be explored online (https://ericlarg4.github.io/G4_database.html).

scholarly journals Determination of synthetic ferric chelates used as fertilizers by liquid chromatography-electrospray/mass spectrometry in agricultural matrices

2007 ◽  
Vol 18 (1) ◽  
pp. 37-47 ◽  
Author(s):  
Ana Álvarez-Fernández ◽  
Irene Orera ◽  
Javier Abadía ◽  
Anunciación Abadía
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Electrospray Mass Spectrometry

Electrospray mass spectrometry of organometallic compounds

2000 ◽  
Vol 200 (1-3) ◽  
pp. 387-401 ◽  
Author(s):  
John C Traeger
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Mass Spectrometry ◽  
Organometallic Compounds
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