WITHDRAWN: Structural and biophysical insight into dual site binding of the protoberberine alkaloid palmatine to parallel G-quadruplex DNA using NMR, fluorescence and circular dichroism spectroscopy

Biochimie ◽  
2018 ◽  
Author(s):  
Kumar Padmapriya ◽  
Ritu Barthwal
Keyword(s):  
Circular Dichroism ◽  
Circular Dichroism Spectroscopy ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Protoberberine Alkaloid ◽  
Circular Dichroïsm ◽  
Insight Into ◽  
Dual Site ◽  
Site Binding

scholarly journals Interaction of 9-Methoxyluminarine with Different G-Quadruplex Topologies: Fluorescence and Circular Dichroism Studies

2021 ◽  
Vol 22 (19) ◽  
pp. 10399
Author(s):  
Joanna Nowak-Karnowska ◽  
Agata Głuszyńska ◽  
Joanna Kosman ◽  
Grażyna Neunert ◽  
Anna Dembska
Keyword(s):  
Circular Dichroism ◽  
Molecular Targets ◽  
Circular Dichroism Spectroscopy ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Circular Dichroïsm

The interactions of G–quadruplexes of different topologies with highly fluorescent 9-methoxyluminarine ligand 9-MeLM were investigated by fluorescence and circular dichroism spectroscopy. The results showed that 9-methoxyluminarine was able to interact and did not destabilize any investigated molecular targets. The studied compound was selectively quenched by parallel c-MYC G-quadruplex DNA, whereas hybrid and antiparallel G4 topology caused only a negligible decrease in the fluorescence of the ligand. A high decrease of fluorescence of the ligand after binding with c-MYC G-quadruplex suggests that this molecule can be used as a selective probe for parallel G-quadruplexes.

scholarly journals Cationic Porphyrin Induced a Telomeric DNA to G-Quadruplex Form in Water

2008 ◽  
Vol 2008 ◽  
pp. 1-5 ◽  
Author(s):  
Takashi Murashima ◽  
Daichi Sakiyama ◽  
Daisuke Miyoshi ◽  
Masanori Kuriyama ◽  
Takashi Yamada ◽  
...  
Keyword(s):  
Circular Dichroism ◽  
Circular Dichroism Spectroscopy ◽  
Telomeric Repeat ◽  
Telomeric Dna ◽  
Cationic Porphyrin ◽  
G Quadruplex ◽  
Circular Dichroïsm

The formation of the DNA G-quadruplex is induced by the addition of a novel porphyrin carrying four cationic tethers. Circular dichroism spectroscopy reveals that the porphyrin binds toTetrahymenatelomeric repeat to form G-quadruplex under stabilizing-cation-deficient and no buffer conditions.

Insight into the Electronic Structure of Formal Lanthanide(II) Complexes using Magnetic Circular Dichroism Spectroscopy

2019 ◽  
Vol 38 (16) ◽  
pp. 3124-3131 ◽  
Author(s):  
Valerie E. Fleischauer ◽  
Gaurab Ganguly ◽  
David H. Woen ◽  
Nikki J. Wolford ◽  
William J. Evans ◽  
...  
Keyword(s):  
Electronic Structure ◽  
Circular Dichroism ◽  
Magnetic Circular Dichroism ◽  
Circular Dichroism Spectroscopy ◽  
Magnetic Circular Dichroism Spectroscopy ◽  
Circular Dichroïsm ◽  
Insight Into

scholarly journals Vibrational circular dichroism spectroscopy for probing the expression of chirality in mechanically planar chiral rotaxanes

2020 ◽  
Vol 11 (32) ◽  
pp. 8469-8475 ◽  
Author(s):  
Mark A. J. Koenis ◽  
C. S. Chibueze ◽  
M. A. Jinks ◽  
Valentin P. Nicu ◽  
Lucas Visscher ◽  
...  
Keyword(s):  
Circular Dichroism ◽  
Absolute Configuration ◽  
Circular Dichroism Spectroscopy ◽  
Vibrational Circular Dichroism ◽  
Mechanical Bond ◽  
Looking Glass ◽  
Circular Dichroïsm ◽  
Insight Into

Through the looking glass: VCD spectroscopy provides unique insight into how a chiral mechanical bond imposes shape on rotaxanes in solution and allows their absolute configuration to be determined.

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