Luminescent ruthenium polypyridyl complexes with extended ‘dppz’ like ligands as DNA targeting binders and cellular agents

2016 ◽  
Vol 45 (45) ◽  
pp. 18208-18220 ◽  
Author(s):  
Bjørn C. Poulsen ◽  
Sandra Estalayo-Adrián ◽  
Salvador Blasco ◽  
Sandra A. Bright ◽  
John M. Kelly ◽  
...  
Keyword(s):  
Dna Binding ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Ancillary Ligands ◽  
Dna Targeting ◽  
Ruthenium Polypyridyl Complexes

DNA-binding and phototoxicity of Ru(ii) complexes with ligands derived from pyrazinodipyridophenazine and either phen or TAP as ancillary ligands are reported.

Influence of the Attaching Group and Substituted Position in the Photosensitization Behavior of Ruthenium Polypyridyl Complexes

1999 ◽  
Vol 38 (26) ◽  
pp. 6320-6322 ◽  
Author(s):  
Yuan-jun Hou ◽  
Pu-hui Xie ◽  
Bao-wen Zhang ◽  
Yi Cao ◽  
Xu-rui Xiao ◽  
...  
Keyword(s):  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Ruthenium Polypyridyl Complexes

Modulation of Internuclear Communication in Multinuclear Ruthenium(II) Polypyridyl Complexes

2003 ◽  
Vol 68 (8) ◽  
pp. 1467-1487 ◽  
Author(s):  
Wesley R. Browne ◽  
Frances Weldon ◽  
Adrian Guckian ◽  
Johannes G. Vos
Keyword(s):  
Ground State ◽  
Weak Interactions ◽  
Electrochemical Studies ◽  
Protonation State ◽  
Ruthenium Polypyridyl ◽  
Bridging Ligands ◽  
Polypyridyl Complexes ◽  
Bridging Ligand ◽  
Dinuclear Ruthenium ◽  
Ruthenium Polypyridyl Complexes

The syntheses and characterisation of a series of mononuclear and dinuclear ruthenium polypyridyl complexes based on the bridging ligands 1,3-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 1,4-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 2,5-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]thiophene, 2,5-bis-[5-pyrazinyl-1H-1,2,4-triazol-3-yl]thiophene are reported. Electrochemical studies indicate that in these systems, the ground state interaction is critically dependent on the nature of the bridging ligand and its protonation state, with strong and weak interactions being observed for thiophene- and phenylene-bridged complexes, respectively.

scholarly journals Quantitative description of MLCT transitions in ruthenium polypyridyl complexes probed by two-photon absorption spectroscopy

2018 ◽  
Vol 190 ◽  
pp. 03012
Author(s):  
Charles W. Stark ◽  
M. Rammo ◽  
K. Petritšenko ◽  
J. Pahapill ◽  
A. Mikhaylov ◽  
...  
Keyword(s):  
Cross Section ◽  
Quantitative Description ◽  
Photon Absorption ◽  
Charge Transfer Transition ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Ligand Charge Transfer ◽  
Ruthenium Polypyridyl Complexes

Quantitative two-photon absorption (2PA) cross section and 2PA spectrum measurements were used to determine the molecular electric dipole change in the metal-to-ligand charge-transfer transition of ruthenium(II) tris-complexes of 2,2’-bipyridine ([Ru(bpy)3]2+) and 1,10-phenanthroline ([Ru(phen)3]2+) in several solvents.

Sixty Years Young: The Diverse Biological Activities of Metal Polypyridyl Complexes Pioneered by Francis P. Dwyer

2012 ◽  
Vol 65 (9) ◽  
pp. 1325 ◽  
Author(s):  
Nathan L. Kilah ◽  
Eric Meggers
Keyword(s):  
Inorganic Chemistry ◽  
Biological Activities ◽  
Biologically Active ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complexes ◽  
Anti Cancer ◽  
Ruthenium Polypyridyl Complexes ◽  
Medicinal Inorganic Chemistry ◽  
Sixtieth Anniversary

Sixty years ago, the Australian chemist Francis P. Dwyer pioneered the use of ruthenium polypyridyl complexes as biologically active compounds. These chemically inert and configurationally stable complexes revealed an astonishing range of interesting biological activities, such as the inhibition of the enzyme acetylcholinesterase, anti-cancer activity in vivo, and bacteriostatic/bacteriocidal action. This review commemorates the sixtieth anniversary of Dwyer and co-workers’ landmark 1952 publication, summarises their broader achievements in biological inorganic chemistry, and discusses the contribution of this work to the development of modern biological and medicinal inorganic chemistry.

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