Synthesis and pH-responsive self-assembly behavior of a fluorescent amphiphilic triblock copolymer mPEG-b-PCL-b-PDMAEMA-g-PC for the controlled intracellular delivery of doxorubicin

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 27102-27112 ◽  
Author(s):  
Lei Li ◽  
Beibei Lu ◽  
Qikui Fan ◽  
Lulu Wei ◽  
Jianning Wu ◽  
...  
Keyword(s):  
Self Assembly ◽  
Triblock Copolymer ◽  
Intracellular Delivery ◽  
Ph Responsive ◽  
Amphiphilic Triblock Copolymer ◽  
Assembly Behavior

Schematic illustration of the pH-responsive self-assembly of a mPEG-b-PCL-b-PDMAEMA-g-PC copolymer with fluorescent coumarin units for controlling DOX release.

PTPFCBBMA-b-PEG-b-PTPFCBBMA amphiphilic triblock copolymer: Synthesis and self-assembly behavior

Polymer ◽  
2009 ◽  
Vol 50 (11) ◽  
pp. 2341-2348 ◽  
Author(s):  
Liang Tong ◽  
Zhong Shen ◽  
Dong Yang ◽  
Sheng Chen ◽  
Yongjun Li ◽  
...  
Keyword(s):  
Self Assembly ◽  
Triblock Copolymer ◽  
Amphiphilic Triblock Copolymer ◽  
Assembly Behavior

Synthesis and self-assembly behavior of pH-responsive star-shaped POSS-(PCL-P(DMAEMA-co-PEGMA))16 inorganic/organic hybrid block copolymer for the controlled intracellular delivery of doxorubicin

RSC Advances ◽  
2016 ◽  
Vol 6 (66) ◽  
pp. 61630-61640 ◽  
Author(s):  
Lei Li ◽  
Beibei Lu ◽  
Qikui Fan ◽  
Jianning Wu ◽  
Lulu Wei ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Self Assembly ◽  
Tumor Tissue ◽  
Intracellular Delivery ◽  
Ph Responsive ◽  
Acidic Microenvironment ◽  
Organic Hybrid ◽  
Intracellular Release ◽  
Anti Cancer ◽  
Assembly Behavior

Illustration of pH-responsive self-assembly of the star-shaped POSS-(PCL-P(DMAEMA-co-PEGMA))16 copolymer for the efficient intracellular release of anti-cancer drugs triggered by the acidic microenvironment inside the tumor tissue.

Effect of Selective Solvents on Self-Assembly of Cationic Amphiphilic Triblock Copolymers Q-PVBC-b-PS-B-Q-PVBC

2013 ◽  
Vol 787 ◽  
pp. 245-249
Author(s):  
Bing Bing Yang ◽  
Yan Shi ◽  
Zhi Feng Fu
Keyword(s):  
Self Assembly ◽  
Triblock Copolymer ◽  
Raft Polymerization ◽  
The Self ◽  
Amphiphilic Block Copolymers ◽  
Selective Solvent ◽  
Selective Solvents ◽  
Amphiphilic Triblock Copolymer ◽  
Ps I ◽  
Assembly Behavior

Self-assembly behavior of an cationic amphiphilic triblock copolymer Q-PVBC -b-PS-b-Q-PVBC in DMF/water and DMF/methanol were studied. Well defined triblock copolymer PVBC-b-PS-b-PVBC was synthesized by RAFT polymerization and the cationic amphiphilic block copolymers Q-PVBC-b-PS-b-Q-PVBC was obtained by the quaternization of hydrophobic precursors with triethylamine. It is concluded that that selective solvents had a great effect on the self-assemble morphologies of the polymer. Comparing to the micelles treating water as the selective solvent, the aggregates using methanol were irregular spheres and had larger diameter.

PDMAEMA-b-PPOA-b-PDMAEMA double-bond-containing amphiphilic triblock copolymer: synthesis, characterization, and pH-responsive self-assembly

2017 ◽  
Vol 8 (43) ◽  
pp. 6628-6635 ◽  
Author(s):  
Aishun Ding ◽  
Guolin Lu ◽  
Hao Guo ◽  
Xiaoyu Huang
Keyword(s):  
Free Radical ◽  
Double Bond ◽  
Radical Polymerization ◽  
Self Assembly ◽  
Triblock Copolymer ◽  
Free Radical Polymerization ◽  
Ph Responsive ◽  
Amphiphilic Triblock Copolymer ◽  
Aba Triblock Copolymer

This article reports a new pH-responsive double-bond-containing ABA triblock copolymer synthesized via a combination of free radical polymerization and SET-LRP.

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