Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways

This study involved the identification and characterization of ponatinib by LC-MS/MS. Additionally ponatinib reactive metabolites were also investigated using KCN as a trapping agent, showing the formation of four reactive cyano adducts.

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Identification and Characterization of Terpenoid Lactones and Flavonoids from Ethanolic Extract ofAndrographis Paniculata(Burm.f.) Nees Using Liquid Chromatography/Tandem Mass Spectrometry

Separation Science Plus ◽

10.1002/sscp.201800106 ◽

2018 ◽

Vol 1 (12) ◽

pp. 762-770 ◽

Cited By ~ 2

Author(s):

Sunil Kumar ◽

Awantika Singh ◽

Vikas Bajpai ◽

Kulwant R. Sharma ◽

Brijesh Kumar

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Ethanolic Extract ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Identification And Characterization

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Identification and characterization of reaction products of 5-hydroxytryptamine with methylglyoxal and glyoxal by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8195 ◽

2018 ◽

Vol 32 (17) ◽

pp. 1529-1539 ◽

Cited By ~ 2

Author(s):

L. Sai Sachin ◽

R. Nagarjuna Chary ◽

P. Pavankumar ◽

S. Prabhakar

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Reaction Products ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Identification And Characterization

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Identification and characterization of five new classes of chlorogenic acids in burdock (Arctium lappa L.) roots by liquid chromatography/tandem mass spectrometry

Food & Function ◽

10.1039/c0fo00125b ◽

2011 ◽

Vol 2 (1) ◽

pp. 63-71 ◽

Cited By ~ 34

Author(s):

Rakesh Jaiswal ◽

Nikolai Kuhnert

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Chlorogenic Acids ◽

Arctium Lappa ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Identification And Characterization

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Identification and characterization of the new designer drug 4′-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography–tandem mass spectrometry (LC–MS/MS) screening method for seven different methcathinone analogs

Forensic Science International ◽

10.1016/j.forsciint.2011.03.019 ◽

2011 ◽

Vol 210 (1-3) ◽

pp. 213-220 ◽

Cited By ~ 62

Author(s):

Péter Jankovics ◽

András Váradi ◽

László Tölgyesi ◽

Szilvia Lohner ◽

Júlia Németh-Palotás ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Screening Method ◽

Designer Drug ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Identification And Characterization

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Correction: Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways

RSC Advances ◽

10.1039/c7ra90020a ◽

2017 ◽

Vol 7 (18) ◽

pp. 10848-10848

Author(s):

Adnan A. Kadi ◽

Hany W. Darwish ◽

Mohamed W. Attwa ◽

Sawsan M. Amer

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Reactive Metabolites ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Correction for ‘Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways’ by Adnan A. Kadi et al., RSC Adv., 2016, 6, 72575–72585.

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