Downregulation of MIM protein inhibits the cellular endocytosis process of magnetic nanoparticles in macrophages

RSC Advances ◽  
2016 ◽  
Vol 6 (99) ◽  
pp. 96635-96643 ◽  
Author(s):  
Peng Zhao ◽  
Meng Cao ◽  
Lina Song ◽  
Hao Wu ◽  
Ke Hu ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Molecular Basis ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Raw 264.7 ◽  
Positive Role

MIM plays a positive role in the RAW 264.7 cellular endocytosis process of iron oxide nanoparticles mainly in clathrin-mediated pathway, which is a meaningful molecular basis for biomedical applications of nanomaterials.

Iron Oxide Nanoparticles: An Insight into their Biomedical Applications

2015 ◽  
Vol 22 (15) ◽  
pp. 1808-1828 ◽  
Author(s):  
Diana Couto ◽  
Marisa Freitas ◽  
Felix Carvalho ◽  
Eduarda Fernandes
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Insight Into

Evaluation of Surface-modified Superparamagnetic Iron Oxide Nanoparticles to Optimize Bacterial Immobilization for Bio-separation with the Least Inhibitory Effect on Microorganism Activity

2020 ◽  
Vol 10 (2) ◽  
pp. 166-174
Author(s):  
Mehdi Khoshneviszadeh ◽  
Sarah Zargarnezhad ◽  
Younes Ghasemi ◽  
Ahmad Gholami
Keyword(s):  
Iron Oxide ◽  
Amino Acid ◽  
Magnetic Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Surface Coating ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Surface Charges ◽  
Surface Modified

Background: Magnetic cell immobilization has been introduced as a novel, facile and highly efficient approach for cell separation. A stable attachment between bacterial cell wall with superparamagnetic iron oxide nanoparticles (SPIONs) would enable the microorganisms to be affected by an outer magnetic field. At high concentrations, SPIONs produce reactive oxygen species in cytoplasm, which induce apoptosis or necrosis in microorganisms. Choosing a proper surface coating could cover the defects and increase the efficiency. Methods: In this study, asparagine, APTES, lipo-amino acid and PEG surface modified SPIONs was synthesized by co-precipitation method and characterized by FTIR, TEM, VSM, XRD, DLS techniques. Then, their protective effects against four Gram-positive and Gram-negative bacterial strains including Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were examined through microdilution broth and compared to naked SPION. Results: The evaluation of characterization results showed that functionalization of magnetic nanoparticles could change their MS value, size and surface charges. Also, the microbial analysis revealed that lipo-amino acid coated magnetic nanoparticles has the least adverse effect on microbial strain among tested SPIONs. Conclusion: This study showed lipo-amino acid could be considered as the most protective and even promotive surface coating, which is explained by its optimizing effect on cell penetration and negligible reductive effects on magnetic properties of SPIONs. lipo-amino acid coated magnetic nanoparticles could be used in microbial biotechnology and industrial microbiology.

Bio-inspired encapsulation and functionalization of iron oxide nanoparticles for biomedical applications

2020 ◽  
Vol 122 ◽  
pp. 109371 ◽  
Author(s):  
Samson O. Aisida ◽  
Paul A. Akpa ◽  
Ishaq Ahmad ◽  
Ting-kai Zhao ◽  
M. Maaza ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles

Dynamic Investigation of Interaction of Biocompatible Iron Oxide Nanoparticles with Epithelial Cells for Biomedical Applications

2013 ◽  
Vol 9 (9) ◽  
pp. 1556-1569 ◽  
Author(s):  
Alice Panariti ◽  
Barbara Lettiero ◽  
Rodica Alexandrescu ◽  
Maddalena Collini ◽  
Laura Sironi ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Epithelial Cells ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Dynamic Investigation

Photo-fluorescent and magnetic properties of iron oxide nanoparticles for biomedical applications

Nanoscale ◽  
2015 ◽  
Vol 7 (18) ◽  
pp. 8209-8232 ◽  
Author(s):  
Donglu Shi ◽  
M. E. Sadat ◽  
Andrew W. Dunn ◽  
David B. Mast
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Physical Properties ◽  
Iron Oxide Nanoparticles ◽  
Basic Science ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
Nanometer Range

Iron oxide exhibits fascinating physical properties especially in the nanometer range, not only from the standpoint of basic science, but also for a variety of engineering, particularly biomedical applications.

One-Pot Synthesis of Iron Oxide Nanoparticles with Functional Silane Shells: A Versatile General Precursor for Conjugations and Biomedical Applications

Langmuir ◽  
2013 ◽  
Vol 29 (34) ◽  
pp. 10850-10858 ◽  
Author(s):  
Vinith Yathindranath ◽  
Zhizhi Sun ◽  
Matthew Worden ◽  
Lynda J. Donald ◽  
James A. Thliveris ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles ◽  
One Pot ◽  
One Pot Synthesis

Highly monodisperse water-dispersable iron oxide nanoparticles for biomedical applications

2010 ◽  
Vol 20 (36) ◽  
pp. 7842 ◽  
Author(s):  
Andreas Hofmann ◽  
Steffen Thierbach ◽  
Annetta Semisch ◽  
Andrea Hartwig ◽  
Matthias Taupitz ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Oxide Nanoparticles
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