scholarly journals Differences in cisplatin distribution in sensitive and resistant ovarian cancer cells: a TEM/NanoSIMS study

Metallomics ◽  
2017 ◽  
Vol 9 (10) ◽  
pp. 1413-1420 ◽  
Author(s):  
Ronald F. S. Lee ◽  
Tina Riedel ◽  
Stéphane Escrig ◽  
Catherine Maclachlan ◽  
Graham W. Knott ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Acquired Resistance ◽  
Cancer Drug ◽  
Ovarian Cancer Cells ◽  
Anti Cancer

Cisplatin is a widely used anti-cancer drug, but its effect is often limited by acquired resistance to the compound during treatment.

scholarly journals Searching for a New Anti‐Cancer Drug: Investigation of KY Hemp‐Induced Apoptosis in Ovarian Cancer Cells

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Wasana K. Sumanasekera ◽  
Christina Johnson ◽  
Anh‐Thoa Pham ◽  
Brijesh Patel ◽  
Anjali Sivamohan ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Cancer Drug ◽  
Ovarian Cancer Cells ◽  
Drug Investigation ◽  
Anti Cancer ◽  
Induced Apoptosis

Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway

2012 ◽  
Vol 258 (1) ◽  
pp. 72-81 ◽  
Author(s):  
Miran Jo ◽  
Mi Hee Park ◽  
Pushpa Saranya Kollipara ◽  
Byeong Jun An ◽  
Ho Sueb Song ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Death Receptors ◽  
Bee Venom ◽  
Ovarian Cancer Cells ◽  
Stat3 Pathway ◽  
Venom Toxin ◽  
Anti Cancer

scholarly journals Anticancer effects of novel resveratrol analogues on human ovarian cancer cells

2017 ◽  
Vol 13 (6) ◽  
pp. 1131-1141 ◽  
Author(s):  
Daniele Vergara ◽  
Stefania De Domenico ◽  
Andrea Tinelli ◽  
Eleonora Stanca ◽  
Loretta L. Del Mercato ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Molecular Mechanisms ◽  
Ovarian Cancer Cells ◽  
Human Ovarian Cancer ◽  
Anticancer Effects ◽  
Anti Cancer ◽  
Resveratrol Analogues

We describe the molecular mechanisms of the action of novel trans-restricted analogues of resveratrol with enhanced anti-cancer properties.

scholarly journals Heteroarotinoids with Anti-Cancer Activity Against Ovarian Cancer Cells

2007 ◽  
Vol 1 (1) ◽  
pp. 11-23 ◽  
Author(s):  
Thanh C. Le ◽  
K. Darrell Berlin ◽  
Stacy D. Benson ◽  
Margaret A. Eastman ◽  
Gianna Bell-Eunice ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Ovarian Cancer Cells ◽  
Anti Cancer ◽  
Cancer Activity

Heteroarotinoids with Anti-Cancer Activity Against Ovarian Cancer Cells

2007 ◽  
Vol 1 (1) ◽  
pp. 11-23
Author(s):  
Thanh C. Le ◽  
K. Darrell Berlin ◽  
Stacy D. Benson ◽  
Margaret A. Eastman ◽  
Gianna Bell-Eunice ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Ovarian Cancer Cells ◽  
Anti Cancer ◽  
Cancer Activity

RHAMM-Target Peptides Inhibit Proliferation and Viability of Cancer Cells

2021 ◽  
Vol 11 (4) ◽  
pp. 12252-12266
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Ovarian Cancer Cells ◽  
Targeted Cancer Therapy ◽  
Proliferation Assay ◽  
Cancer Breast ◽  
Low Concentrations ◽  
Skov3 Cells ◽  
Anti Cancer ◽  
The World

The incidence of cancer in the world is growing exponentially. Therefore, the search for targeted cancer therapy methods is the most urgent and actively developing the biomedicine field. This work is devoted to studying RHAMM-target peptides' effect on the proliferation and viability of ovarian cancer, prostate cancer, breast carcinoma, and adenocarcinoma of the breast duct cells. Cell proliferation was examined by a BrdU-based proliferation assay. Cell viability was assayed by the fluorescence method. It has been established that RHAMM-target peptides at a concentration of 2х10-7 M inhibited on ~ 55 % proliferation of MDA-MB-231 cells, on ~ 85 % proliferation of PC3m-LN4, and ~ 50 % proliferation of SKOV3 cells for 24 h. The results showed that the peptides inhibited the viability of ovarian cancer cells. In particular, peptide EEDFGEEAEEEA inhibited ovarian cancer cells' viability by 54%, peptide VEGEGEEGEEY by 63%, and peptide FTEAESNMNDLV by 57%. RHAMM-target peptides did not affect fibroblasts (non-tumor cells) and fibroblasts RHAMM(-/-). This work showed that RHAMM-target peptides at low concentrations of inhibited cancer cells' proliferation and viability. This effect was RHAMM mediated. RHAMM-target peptides are promising candidates for anti-cancer drugs.

Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells

2020 ◽  
Vol 28 (1) ◽  
pp. 115244 ◽  
Author(s):  
Krishna Kumar Gnanasekaran ◽  
Tim Pouland ◽  
Richard A. Bunce ◽  
K. Darrell Berlin ◽  
Suaad Abuskhuna ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Ovarian Cancer Cells ◽  
Anti Cancer
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