Chitosan/gelatin porous scaffolds assembled with conductive poly(3,4-ethylenedioxythiophene) nanoparticles for neural tissue engineering

2017 ◽  
Vol 5 (24) ◽  
pp. 4774-4788 ◽  
Author(s):  
Shuping Wang ◽  
Changkai Sun ◽  
Shui Guan ◽  
Wenfang Li ◽  
Jianqiang Xu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Interfacial Polymerization ◽  
Porous Scaffold ◽  
Neural Tissue ◽  
Porous Scaffolds ◽  
Neural Tissue Engineering ◽  
Electrically Conductive

An electrically conductive scaffold was prepared by assembling PEDOT on a chitosan/gelatin porous scaffold via in situ interfacial polymerization.

Enhanced Cellular Activity on Conducting Polymer

2021 ◽  
pp. 734-773
Author(s):  
Rajiv Borah ◽  
Ashok Kumar
Keyword(s):  
Tissue Engineering ◽  
Conducting Polymer ◽  
Neural Tissue ◽  
Neuronal Model ◽  
Neural Tissue Engineering ◽  
Electrically Conductive ◽  
Pc12 Cell Line ◽  
Nih 3T3

This chapter includes detailed review of the research undertaken with conducting polymer (CP) based composites with chitosan (Ch) for tissue engineering till date. The beneficial role of electrically conductive biomaterials has been discussed with the possible strategies to overcome the shortcomings of CP alone through blending with Ch due to its excellent biocompatibility, biodegradability, and bioactivity. Additionally, this embodiment deals with the optimization and characterization of electrically conductive, biocompatible and biodegradable Polyaniline: Chitosan (PAni:Ch) nanocomposites as cell culture substrates for MDA-MB-231 and NIH 3T3 fibroblast in order to examine the combined effect of nanofiber structure and surface modification on cell-biomaterial interactions. The nanocomposites were further checked as a conductive scaffold for electrical stimulation of a neuronal model PC12 cell line in order to explore the potential of the materials in neural tissue engineering.

Enhanced Cellular Activity on Conducting Polymer

2019 ◽  
pp. 150-189
Author(s):  
Rajiv Borah ◽  
Ashok Kumar
Keyword(s):  
Tissue Engineering ◽  
Conducting Polymer ◽  
Neural Tissue ◽  
Neuronal Model ◽  
Neural Tissue Engineering ◽  
Electrically Conductive ◽  
Pc12 Cell Line ◽  
Nih 3T3

This chapter includes detailed review of the research undertaken with conducting polymer (CP) based composites with chitosan (Ch) for tissue engineering till date. The beneficial role of electrically conductive biomaterials has been discussed with the possible strategies to overcome the shortcomings of CP alone through blending with Ch due to its excellent biocompatibility, biodegradability, and bioactivity. Additionally, this embodiment deals with the optimization and characterization of electrically conductive, biocompatible and biodegradable Polyaniline: Chitosan (PAni:Ch) nanocomposites as cell culture substrates for MDA-MB-231 and NIH 3T3 fibroblast in order to examine the combined effect of nanofiber structure and surface modification on cell-biomaterial interactions. The nanocomposites were further checked as a conductive scaffold for electrical stimulation of a neuronal model PC12 cell line in order to explore the potential of the materials in neural tissue engineering.

Chitosan/gelatin porous scaffolds containing hyaluronic acid and heparan sulfate for neural tissue engineering

2012 ◽  
Vol 24 (8) ◽  
pp. 999-1014 ◽  
Author(s):  
Shui Guan ◽  
Xiu-Li Zhang ◽  
Xiao-Min Lin ◽  
Tian-Qing Liu ◽  
Xue-Hu Ma ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Heparan Sulfate ◽  
Neural Tissue ◽  
Porous Scaffolds ◽  
Neural Tissue Engineering

In situ synthesis of conductive polypyrrole on electrospun cellulose nanofibers: scaffold for neural tissue engineering

Cellulose ◽  
2015 ◽  
Vol 22 (3) ◽  
pp. 1459-1467 ◽  
Author(s):  
Johannes Thunberg ◽  
Theodoros Kalogeropoulos ◽  
Volodymyr Kuzmenko ◽  
Daniel Hägg ◽  
Sara Johannesson ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cellulose Nanofibers ◽  
Neural Tissue ◽  
In Situ Synthesis ◽  
Neural Tissue Engineering ◽  
Conductive Polypyrrole

scholarly journals Spidroin Silk Fibers with Bioactive Motifs of Extracellular Proteins for Neural Tissue Engineering

ACS Omega ◽  
2021 ◽  
Author(s):  
Veronica A. Revkova ◽  
Konstantin V. Sidoruk ◽  
Vladimir A. Kalsin ◽  
Pavel A. Melnikov ◽  
Mikhail A. Konoplyannikov ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Neural Tissue ◽  
Extracellular Proteins ◽  
Neural Tissue Engineering ◽  
Silk Fibers

scholarly journals Electrospun Nanofibrous Materials for Neural Tissue Engineering

Polymers ◽  
2011 ◽  
Vol 3 (1) ◽  
pp. 413-426 ◽  
Author(s):  
Yee-Shuan Lee ◽  
Treena Livingston Arinzeh
Keyword(s):  
Tissue Engineering ◽  
Neural Tissue ◽  
Neural Tissue Engineering

Directing Axonal Growth: A Review on the Fabrication of Fibrous Scaffolds That Promotes the Orientation of Axons

Gels ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 25
Author(s):  
Devindraan Sirkkunan ◽  
Belinda Pingguan-Murphy ◽  
Farina Muhamad
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Neuronal Cells ◽  
Neural Tissue ◽  
Axonal Growth ◽  
Structural Proteins ◽  
Neural Cells ◽  
Neural Tissue Engineering ◽  
Fibrous Scaffolds ◽  
Specialized Function

Tissues are commonly defined as groups of cells that have similar structure and uniformly perform a specialized function. A lesser-known fact is that the placement of these cells within these tissues plays an important role in executing its functions, especially for neuronal cells. Hence, the design of a functional neural scaffold has to mirror these cell organizations, which are brought about by the configuration of natural extracellular matrix (ECM) structural proteins. In this review, we will briefly discuss the various characteristics considered when making neural scaffolds. We will then focus on the cellular orientation and axonal alignment of neural cells within their ECM and elaborate on the mechanisms involved in this process. A better understanding of these mechanisms could shed more light onto the rationale of fabricating the scaffolds for this specific functionality. Finally, we will discuss the scaffolds used in neural tissue engineering (NTE) and the methods used to fabricate these well-defined constructs.

Sign in / Sign up

Export Citation Format

Share Document