An ultrasensitive electrochemical immunoassay based on a proximity hybridization-triggered three-layer cascade signal amplification strategy

The Analyst ◽  
2019 ◽  
Vol 144 (2) ◽  
pp. 634-640 ◽  
Author(s):  
Erhu Xiong ◽  
Ling Jiang
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunoassay ◽  
Amplification Strategy

An ultrasensitive electrochemical immunoassay based on a proximity hybridization-triggered three-layer cascade signal amplification strategy.

Electrochemical immunoassay for procalcitonin antigen detection based on signal amplification strategy of multiple nanocomposites

2014 ◽  
Vol 51 ◽  
pp. 310-316 ◽  
Author(s):  
Yi-Shan Fang ◽  
Hai-Ying Wang ◽  
Li-Shi Wang ◽  
Ju-Fang Wang
Keyword(s):  
Signal Amplification ◽  
Antigen Detection ◽  
Electrochemical Immunoassay ◽  
Amplification Strategy

A novel electrochemical strategy based on porous 3D graphene-starch architecture and silver deposition for ultrasensitive detection of neuron-specific enolase

The Analyst ◽  
2019 ◽  
Vol 144 (6) ◽  
pp. 2186-2194 ◽  
Author(s):  
Yishan Fang ◽  
Yanping Li ◽  
Ming Zhang ◽  
Bo Cui ◽  
Qiong Hu ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Neuron Specific Enolase ◽  
Ultrasensitive Detection ◽  
Electrochemical Immunoassay ◽  
Silver Deposition ◽  
3D Graphene ◽  
Amplification Strategy

This work was aimed at designing a novel and ultrasensitive electrochemical immunoassay strategy to detect neuron-specific enolase (NSE) with a triple signal amplification strategy.

Electrochemical immunoassay for carcinoembryonic antigen based on signal amplification strategy of nanotubular mesoporous PdCu alloy

2012 ◽  
Vol 36 (1) ◽  
pp. 6-11 ◽  
Author(s):  
Yanyan Cai ◽  
He Li ◽  
Yuyang Li ◽  
Yanfang Zhao ◽  
Hongmin Ma ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Signal Amplification ◽  
Electrochemical Immunoassay ◽  
Amplification Strategy

scholarly journals Dual-Signal Amplification Strategy for Sensitive MicroRNA Detection Based on Rolling Circle Amplification and Enzymatic Repairing Amplification

ACS Omega ◽  
2020 ◽  
Vol 5 (50) ◽  
pp. 32738-32743
Author(s):  
Fubing Xiao ◽  
Jie Liu ◽  
Qinghui Guo ◽  
Zhibo Du ◽  
Hong Li ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Rolling Circle Amplification ◽  
Rolling Circle ◽  
Microrna Detection ◽  
Amplification Strategy ◽  
Dual Signal Amplification

scholarly journals MiRNA Detection Using a Rolling Circle Amplification and RNA-Cutting Allosteric Deoxyribozyme Dual Signal Amplification Strategy

Biosensors ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 222
Author(s):  
Chenxin Fang ◽  
Ping Ouyang ◽  
Yuxing Yang ◽  
Yang Qing ◽  
Jialun Han ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Rolling Circle Amplification ◽  
Padlock Probe ◽  
Rolling Circle ◽  
Sensing Platform ◽  
Mirna Detection ◽  
Substrate Cleavage ◽  
Amplification Strategy ◽  
Circular Template ◽  
Dual Signal Amplification

A microRNA (miRNA) detection platform composed of a rolling circle amplification (RCA) system and an allosteric deoxyribozyme system is proposed, which can detect miRNA-21 rapidly and efficiently. Padlock probe hybridization with the target miRNA is achieved through complementary base pairing and the padlock probe forms a closed circular template under the action of ligase; this circular template results in RCA. In the presence of DNA polymerase, RCA proceeds and a long chain with numerous repeating units is formed. In the presence of single-stranded DNA (H1 and H2), multi-component nucleic acid enzymes (MNAzymes) are formed that have the ability to cleave substrates. Finally, substrates containing fluorescent and quenching groups and magnesium ions are added to the system to activate the MNAzyme and the substrate cleavage reaction, thus achieving fluorescence intensity amplification. The RCA–MNAzyme system has dual signal amplification and presents a sensing platform that demonstrates broad prospects in the analysis and detection of nucleic acids.

Naked-Eye Detection of Hg(II) Ions by Visible Light-Induced Polymerization Initiated by a Hg(II)-Selective Photoredox Catalyst

2021 ◽  
Author(s):  
Hyungwook Kim ◽  
Young Jae Jung ◽  
Jungkyu K. Lee
Keyword(s):  
Visible Light ◽  
Signal Amplification ◽  
Eye Detection ◽  
Naked Eye ◽  
Turn On ◽  
Novel Strategy ◽  
Amplification Strategy ◽  
Naked Eye Detection

We developed a novel strategy for signal amplification strategy using a visible light-induced photopolymerization, initiated by a selective turn-on photoredox catalyst. As photoredox catalysts, fluorescein derivatives are able to initiate...

A signal amplification strategy based on peptide self-assembly for the identification of amyloid-β oligomer

2021 ◽  
pp. 129697
Author(s):  
Yujin Huang ◽  
Baole Zhang ◽  
Liang Yuan ◽  
Lei Liu
Keyword(s):  
Self Assembly ◽  
Signal Amplification ◽  
Amyloid Β ◽  
Amplification Strategy

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

Sign in / Sign up

Export Citation Format

Share Document