scholarly journals Automated high-content phenotyping from the first larval stage till the onset of adulthood of the nematode Caenorhabditis elegans

Lab on a Chip ◽  
2019 ◽  
Vol 19 (1) ◽  
pp. 120-135 ◽  
Author(s):  
Huseyin Baris Atakan ◽  
Matteo Cornaglia ◽  
Laurent Mouchiroud ◽  
Johan Auwerx ◽  
Martin A. M. Gijs
Keyword(s):  
Caenorhabditis Elegans ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Dietary Restriction ◽  
Larval Stage ◽  
Disease Development ◽  
Nematode Caenorhabditis Elegans

We performed automated high-content phenotyping of Caenorhabditis elegans and demonstrated that dietary restriction slows down Huntington's disease development.

Rutin protects Huntington's disease through the insulin/IGF1 (IIS) signaling pathway and autophagy activity: Study in Caenorhabditis elegans model

2020 ◽  
Vol 141 ◽  
pp. 111323 ◽  
Author(s):  
Larissa Marafiga Cordeiro ◽  
Marina Lopes Machado ◽  
Aline Franzen da Silva ◽  
Fabiane Bicca Obetine Baptista ◽  
Tássia Limana da Silveira ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Signaling Pathway ◽  
Autophagy Activity

scholarly journals Identification of Potential Therapeutic Drugs for Huntington's Disease using Caenorhabditis elegans

PLoS ONE ◽  
2007 ◽  
Vol 2 (6) ◽  
pp. e504 ◽  
Author(s):  
Cindy Voisine ◽  
Hemant Varma ◽  
Nicola Walker ◽  
Emily A. Bates ◽  
Brent R. Stockwell ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Therapeutic Drugs

scholarly journals Dietary Restriction in the Nematode Caenorhabditis elegans

2005 ◽  
Vol 60 (9) ◽  
pp. 1125-1131 ◽  
Author(s):  
K. Houthoofd ◽  
T. E. Johnson ◽  
J. R. Vanfleteren
Keyword(s):  
Caenorhabditis Elegans ◽  
Dietary Restriction ◽  
Nematode Caenorhabditis Elegans

L07 The functional rating taskforce for pre-huntington's disease: development of the furst-21 scale

2012 ◽  
Vol 83 (Suppl 1) ◽  
pp. A45.2-A45
Author(s):  
A Vaccarino ◽  
K Anderson ◽  
B Borowsky ◽  
D Craufurd ◽  
J Giuliano ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Disease Development

Neuroprotective effects of rutin on ASH neurons in Caenorhabditis elegans model of Huntington’s disease

2021 ◽  
pp. 1-14
Author(s):  
Larissa Marafiga Cordeiro ◽  
Marcell Valandro Soares ◽  
Aline Franzen da Silva ◽  
Marina Lopes Machado ◽  
Fabiane Bicca Obetine Baptista ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Neuroprotective Effects

Association of several small heat-shock proteins with reproductive tissues in the nematode Caenorhabditis elegans

2000 ◽  
Vol 351 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Lily DING ◽  
E. Peter M. CANDIDO
Keyword(s):  
Caenorhabditis Elegans ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Larval Stage ◽  
Small Heat Shock Proteins ◽  
Nematode Caenorhabditis Elegans ◽  
Male Tail ◽  
Reproductive Tissues ◽  
Fourth Larval Stage ◽  
Shock Proteins

Immunohistochemical data on 10 of the 14 small heat-shock (smHSPs) proteins in fourth larval stage and adult Caenorhabditis elegans show that the tissues expressing the greatest number of smHSPs are vulva (HSP12s, HSP43 and, under stress, HSP16s) and spermatheca (HSP12s, HSP25, HSP43 and, under stress, HSP16s). HSP43 is also expressed in male tail structures, and following heat-shock HSP16s are expressed in spermatids and spermatozoa.

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