Microwave assisted one-pot synthetic route to imidazo[1,2-a]pyrimidine derivatives of imidazo/triazole clubbed pyrazole and their pharmacological screening

2018 ◽  
Vol 42 (15) ◽  
pp. 12666-12676 ◽  
Author(s):  
Pratibha Prasad ◽  
Anirudhdha G. Kalola ◽  
Manish P. Patel
Keyword(s):  
Synthetic Route ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Microwave Assisted ◽  
Pharmacological Screening ◽  
Derivatives Of

An efficient synthetic microwave-assisted, one-pot three-component condensation route for imidazo[1,2-a]pyrimidine derivatives of imidazole 4/triazole 5 clubbed pyrazole catalysed by ecofriendly base KOH.

Probing the Reactivity of 2,4-Dichlorofuro[3,4-d]pyrimidin-7-one: A Versatile and Underexploited Scaffold to Generate Substituted or Fused Pyrimidine Derivatives

Synlett ◽  
2019 ◽  
Vol 30 (17) ◽  
pp. 2010-2014
Author(s):  
Paolo Vincetti ◽  
Gabriele Costantino ◽  
Maria Grazia Martina ◽  
Marco Radi
Keyword(s):  
Chemical Reactivity ◽  
Pyrimidine Derivatives ◽  
Reaction Conditions ◽  
One Pot ◽  
Microwave Assisted ◽  
Set Up

Herein, we describe the results of our investigation on the chemical reactivity and versatility of a poorly explored scaffold: 2,4-dichlorofuro[3,4-d]pyrimidin-7-one (3). Highly functionalized pyrimidines can be obtained with a divergent approach by reacting the key intermediate 3 with different amine nucleophiles under carefully controlled reaction conditions. The set-up of a microwave-assisted one-pot, two- or three-step protocol to rapidly generate 2,4,5,6-tetrasubstituted or fused pyrimidines is also reported.

ChemInform Abstract: Microwave Assisted One-Pot Synthesis of Pyrazine Derivatives of Pentacyclic Triterpenoids and Their Biological Activity.

ChemInform ◽  
2012 ◽  
Vol 43 (7) ◽  
pp. no-no
Author(s):  
Pranab Ghosh ◽  
Md. Golam Rasul ◽  
Madhumita Chakraborty ◽  
Amitava Mandal ◽  
Aniruddha Saha
Keyword(s):  
Biological Activity ◽  
One Pot ◽  
Pentacyclic Triterpenoids ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
Derivatives Of

ChemInform Abstract: An Efficient One-Pot and Solvent-Free Synthesis of Chromeno[2,3-d]pyrimidine Derivatives: Microwave Assisted Reaction.

ChemInform ◽  
2010 ◽  
Vol 41 (40) ◽  
pp. no-no
Author(s):  
Afsaneh Zonouzi ◽  
Mojtaba Biniaz ◽  
Roghieh Mirzazadeh ◽  
Merzieh Talebi ◽  
Seik Weng Ng
Keyword(s):  
Solvent Free ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Microwave Assisted ◽  
Solvent Free Synthesis

A facile one pot synthesis of novel pyrimidine derivatives of 1,5-benzodiazepines via domino reaction and their antibacterial evaluation

2019 ◽  
Vol 163 ◽  
pp. 105648 ◽  
Author(s):  
Apoorva Misra ◽  
Sonika Jain ◽  
Dharma Kishore ◽  
Vivek Dave ◽  
Kakarla Raghava Reddy ◽  
...  
Keyword(s):  
Domino Reaction ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
One Pot Synthesis ◽  
Derivatives Of ◽  
Antibacterial Evaluation

An Efficient One-Pot and Solvent-Free Synthesis of Chromeno[2,3-d]pyrimidine Derivatives: Microwave Assisted Reaction

Heterocycles ◽  
2010 ◽  
Vol 81 (5) ◽  
pp. 1271 ◽  
Author(s):  
Afsaneh Zonouzi ◽  
Mojtaba Biniaz ◽  
Roghieh Mirzazadeh ◽  
Merzieh Talebi ◽  
Seik Weng Ng
Keyword(s):  
Solvent Free ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Microwave Assisted ◽  
Solvent Free Synthesis

scholarly journals Microwave-assisted one-pot synthesis of some dicyano- methylene derivatives of indenoquinoxaline and tryptanthrin under solvent free conditions

ARKIVOC ◽  
2007 ◽  
Vol 2007 (15) ◽  
pp. 24-30 ◽  
Author(s):  
Javad Azizian ◽  
Mohammad R. Mohammadizadeh ◽  
Shahab Zomorodbakhsh ◽  
Ali A. Mohammadi ◽  
Ali R. Karimi
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Derivatives Of

scholarly journals Efficient microwave-assisted Suzuki–Miyaura cross-coupling reaction of 3-bromo pyrazolo[1,5-a]pyrimidin-5(4H)-one: towards a new access to 3,5-diarylated 7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine derivatives

RSC Advances ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 1287-1302
Author(s):  
Badr Jismy ◽  
Gérald Guillaumet ◽  
Mohamed Akssira ◽  
Abdellatif Tikad ◽  
Mohamed Abarbri
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Synthetic Route ◽  
Pyrimidine Derivatives ◽  
Microwave Assisted ◽  
Cross Coupling Reaction

A convenient and efficient synthetic route to C3-arylated 7-trifluoromethylpyrazolo[1,5-a]pyrimidin-5-one derivatives has been reported starting from 3-bromo-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-one through a Suzuki–Miyaura cross-coupling reaction.

Microwave-assisted one-pot synthesis of pyrimido［4,5-b］quinolines derivatives

2013 ◽  
Vol 30 (6) ◽  
pp. 636-642
Author(s):  
Xueli Zhang ◽  
Zhilan Lin ◽  
Huiling Hu ◽  
Jiaxin He ◽  
Yuan Gao
Keyword(s):  
One Pot ◽  
Microwave Assisted ◽  
One Pot Synthesis

Efficient One-pot microwave-assisted Synthesis and Spectroscopic Characterization of Novel Antitumor and Antimicrobial Hydroxypyrrolidin2-ones

2018 ◽  
Vol 35 (part 1) ◽  
pp. 1-16
Author(s):  
Eman Azmy ◽  
Boshra Awad ◽  
Halima Hefni ◽  
Hanaa Saad ◽  
Affaf Eltoukhy ◽  
...  
Keyword(s):  
Spectroscopic Characterization ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Microwave Assisted

Synthesis of Unnatural Amino Acids via Microwave-assisted Regio-selective One-pot multi-component Reactions of Sulfamidates

2013 ◽  
Vol 17 (20) ◽  
pp. 2323-2331 ◽  
Author(s):  
Nasir Baig ◽  
Rajender Varma
Keyword(s):  
Amino Acids ◽  
Unnatural Amino Acids ◽  
One Pot ◽  
Microwave Assisted
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