Iron promoted C3–H nitration of 2H-indazole: direct access to 3-nitro-2H-indazoles
2018 ◽
Vol 16
(28)
◽
pp. 5113-5118
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Keyword(s):
An efficient C3–H functionalization of indazole has been demonstrated. Notably, this method involves chelation-free radical C–H nitration on 2H-indazole. The radical mechanism was confirmed by control experiments and quantum chemical calculations. The synthetic utility has been proven by the synthesis of bio-relevant benzimidazoindazoles via reductive cyclization.
Keyword(s):
2019 ◽
Vol 21
(48)
◽
pp. 26324-26332
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1992 ◽
Vol 47
(12)
◽
pp. 1775-1778
◽
2006 ◽
Vol 62
(1)
◽
pp. 135-142
◽
Keyword(s):
Keyword(s):
2015 ◽
Vol 135
(10)
◽
pp. 618-623
2020 ◽
2020 ◽