scholarly journals Integrating continuous flow synthesis with in-line analysis and data generation

2018 ◽  
Vol 16 (33) ◽  
pp. 5946-5954 ◽  
Author(s):  
Marcus Baumann

Continuous flow synthesis of fine chemicals has successfully advanced from an academic niche area to a rapidly growing field of its own that directly impacts developments and applications in industrial settings.

2017 ◽  
Vol 2 (3) ◽  
pp. 315-323 ◽  
Author(s):  
Thomas H. Rehm ◽  
Christian Hofmann ◽  
Dorothee Reinhard ◽  
Hans-Joachim Kost ◽  
Patrick Löb ◽  
...  

Fluorine fine chemical synthesis takes a step ahead using integrated NMR online-analysis with a benchtop NMR spectrometer.


2021 ◽  
Vol 19 (5) ◽  
pp. 1115-1121
Author(s):  
Yoshihiro Kon ◽  
Takuya Nakashima ◽  
Akira Yada ◽  
Tadahiro Fujitani ◽  
Shun-ya Onozawa ◽  
...  

Pt-catalyzed continuous flow synthesis of aldehydes from alcohols has been developed, in which various aldehydes for obtaining valuable fine chemicals were given in up to 98% yields for over 5 days by using hydrogen peroxide as an oxidant.


Author(s):  
Lais S. D. Azevedo ◽  
Anderson R. Aguillon ◽  
Marcelo T. Lima ◽  
Raquel A. C. Leão ◽  
Rodrigo O. M. A. de Souza

Author(s):  
Xiaojun Wei ◽  
Stephen V. Kershaw ◽  
Xiaodan Huang ◽  
Mingxia Jiao ◽  
Chau Chun Beh ◽  
...  

Author(s):  
Carsten J. Schmiegel ◽  
Patrik Berg ◽  
Franziska Obst ◽  
Roland Schoch ◽  
Dietmar Appelhans ◽  
...  

2021 ◽  
Vol 27 (18) ◽  
pp. 5653-5657 ◽  
Author(s):  
Andreas Simoens ◽  
Thomas Scattolin ◽  
Thibault Cauwenbergh ◽  
Gianmarco Pisanò ◽  
Catherine S. J. Cazin ◽  
...  

2021 ◽  
pp. 2101616
Author(s):  
Iñigo Torres ◽  
Marta Alcaraz ◽  
Roger Sanchis‐Gual ◽  
Jose A. Carrasco ◽  
Michael Fickert ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 303
Author(s):  
András Gy. Németh ◽  
Renáta Szabó ◽  
György Orsy ◽  
István M. Mándity ◽  
György M. Keserű ◽  
...  

We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditions. The crystallized products were isolated by simple filtration after the removal of the co-solvent, and the sulfur retained in the mother liquid. Presenting a wide range of thioureas synthesized by this procedure confirms the utility of the convenient continuous-flow application of sulfur.


2020 ◽  
Vol 59 (21) ◽  
pp. 8123-8127 ◽  
Author(s):  
Francesco Carraro ◽  
Jason D. Williams ◽  
Mercedes Linares‐Moreau ◽  
Chiara Parise ◽  
Weibin Liang ◽  
...  

ChemSusChem ◽  
2017 ◽  
Vol 10 (17) ◽  
pp. 3435-3444 ◽  
Author(s):  
Tamas Fodi ◽  
Christos Didaskalou ◽  
Jozsef Kupai ◽  
Gyorgy T. Balogh ◽  
Peter Huszthy ◽  
...  

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