Ring-opening metathesis polymerization-induced self-assembly (ROMPISA) of a cisplatin analogue for high drug-loaded nanoparticles

2019 ◽  
Vol 10 (23) ◽  
pp. 2996-3000 ◽  
Author(s):  
Daniel B. Wright ◽  
Maria T. Proetto ◽  
Mollie A. Touve ◽  
Nathan C. Gianneschi
Keyword(s):  
Aqueous Phase ◽  
Self Assembly ◽  
Ring Opening ◽  
Ring Opening Metathesis Polymerization ◽  
One Pot ◽  
Phase Synthesis ◽  
High Drug ◽  
Metathesis Polymerization ◽  
The One ◽  
Micellar Nanoparticles

We report the one-pot aqueous phase synthesis of cisplatin drug loaded micellar nanoparticles using Ring-Opening Metathesis Polymerization-Induced Self-Assembly (ROMPISA).

scholarly journals ROMPI-CDSA: ring-opening metathesis polymerization-induced crystallization-driven self-assembly of metallo-block copolymers

2019 ◽  
Vol 10 (42) ◽  
pp. 9782-9787 ◽  
Author(s):  
Ye Sha ◽  
Md Anisur Rahman ◽  
Tianyu Zhu ◽  
Yujin Cha ◽  
C. Wayne McAlister ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Block Copolymers ◽  
Self Assembly ◽  
Ring Opening ◽  
Ring Opening Metathesis Polymerization ◽  
One Pot ◽  
Metathesis Polymerization ◽  
Induced Crystallization

Two most prevailing self-assembly methods, PISA and CDSA, are combined in one metallo-block copolymer system via one-pot synchronous ROMP, yielding crystalline nanostructures in a mild, fast, scalable and controlled manner.

Aqueous-Phase Ring-Opening Metathesis Polymerization-Induced Self-Assembly

2018 ◽  
Vol 7 (4) ◽  
pp. 401-405 ◽  
Author(s):  
Daniel B. Wright ◽  
Mollie A. Touve ◽  
Matthew P. Thompson ◽  
Nathan C. Gianneschi
Keyword(s):  
Aqueous Phase ◽  
Self Assembly ◽  
Ring Opening ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization

scholarly journals Macromolecular Brushes by Combination of Ring-Opening and Ring-Opening Metathesis Polymerization. Synthesis, Self-Assembly, Thermodynamics, and Dynamics

2018 ◽  
Vol 51 (21) ◽  
pp. 8940-8955 ◽  
Author(s):  
Christiana Nikovia ◽  
Lazaros Theodoridis ◽  
Stelios Alexandris ◽  
Panayiotis Bilalis ◽  
Nikos Hadjichristidis ◽  
...  
Keyword(s):  
Self Assembly ◽  
Ring Opening ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization ◽  
Thermodynamics And Dynamics

scholarly journals Predicting Monomers for Use in Aqueous Ring-Opening Metathesis Polymerization-Induced Self-Assembly

2019 ◽  
Vol 8 (4) ◽  
pp. 466-472 ◽  
Author(s):  
Spyridon Varlas ◽  
Jeffrey C. Foster ◽  
Lucy A. Arkinstall ◽  
Joseph R. Jones ◽  
Robert Keogh ◽  
...  
Keyword(s):  
Self Assembly ◽  
Ring Opening ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization

scholarly journals Enzyme-Responsive Polymer Nanoparticles via Ring-Opening Metathesis Polymerization-Induced Self-Assembly

2019 ◽  
Vol 40 (2) ◽  
pp. 1970004 ◽  
Author(s):  
Daniel B. Wright ◽  
Matthew P. Thompson ◽  
Mollie A. Touve ◽  
Andrea S. Carlini ◽  
Nathan C. Gianneschi
Keyword(s):  
Self Assembly ◽  
Ring Opening ◽  
Polymer Nanoparticles ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization ◽  
Responsive Polymer

Mechanosynthesis of Noels-type NHC-Ruthenium Complexes and Applications in ROMP

2019 ◽  
Author(s):  
François Quintin ◽  
Julien Pinaud ◽  
Frédéric Lamaty ◽  
Xavier Bantreil
Keyword(s):  
Catalytic Activity ◽  
Ring Opening ◽  
Ruthenium Complexes ◽  
High Catalytic Activity ◽  
Imidazolium Salts ◽  
Ring Opening Metathesis Polymerization ◽  
Ball Mills ◽  
Metathesis Polymerization ◽  
Rapid Access ◽  
The One

The use of ball-mills enabled the efficient mechanosynthesis of a variety of N-aryl,N-alkyl imidazolium salts and of corresponding NHC-silver(I) complexes. Transmetalation with ruthenium via mechanochemistry allowed the rapid access (1.5 min to 1 h) to complexes having a similar structure to Noels-type precatalysts. Evaluation of the complexes in the Ring-Opening Metathesis Polymerization of norbornene in different solvent, including non-toxic ones, showed a high catalytic activity for one of them, comparable to the one of Noels catalyst.<br>

Sign in / Sign up

Export Citation Format

Share Document