scholarly journals Hemodynamic loads distinctively impact the secretory profile of biomaterial-activated macrophages – implications for in situ vascular tissue engineering

2020 ◽  
Vol 8 (1) ◽  
pp. 132-147 ◽  
Author(s):  
Tamar B. Wissing ◽  
Eline E. van Haaften ◽  
Suzanne E. Koch ◽  
Bastiaan D. Ippel ◽  
Nicholas A. Kurniawan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Tissue Regeneration ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Activated Macrophages ◽  
Scaffold Degradation

Macrophages play a governing role in material-driven tissue regeneration. Here we show that the paracrine signals of macrophages to direct tissue regeneration and scaffold degradation are dependent on hemodynamic loads.

scholarly journals Engineering the mechanical and biological properties of nanofibrous vascular grafts for in situ vascular tissue engineering

2017 ◽  
Vol 9 (3) ◽  
pp. 035007 ◽  
Author(s):  
Jeffrey J D Henry ◽  
Jian Yu ◽  
Aijun Wang ◽  
Randall Lee ◽  
Jun Fang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Grafts ◽  
Biological Properties ◽  
Vascular Tissue Engineering

Preparation of Electrospun Poly(ε-caprolactone)/Poly(trimethylene carbonate) Blend Scaffold for In Situ Vascular Tissue Engineering

2012 ◽  
Vol 629 ◽  
pp. 60-63
Author(s):  
Tao Jiang ◽  
Guo Quan Zhang ◽  
Hui Li ◽  
Ji Na Xun
Keyword(s):  
Tissue Engineering ◽  
Vascular Graft ◽  
Vascular Tissue ◽  
Electrospinning Process ◽  
Vascular Tissue Engineering ◽  
Trimethylene Carbonate ◽  
Scaffold Materials ◽  
Degradation Time

In the active field of vascular graft research, in situ vascular tissue engineering is a novel concept. This approach aims to use biodegradable synthetic materials. After implantation, the synthetic material progressively degrades and should be replaced by autologous cells. Poly (ε-caprolactone) (PCL) is often used for vascular graft because of its good mechanical strength and its biocompatibility. It is easily processed into micro and nano-fibers by electrospinning to form a porous, cell-friendly scaffold. However, the degradation time of polycaprolactone is too long to match the tissue regeneration time. In this study, poly (ε-caprolactone) /poly (trimethylene carbonate) (PTMC) blend scaffold materials have been prepared for biodegradable vascular graft using an electrospinning process. Because the degradation time of PTMC is shorter than PCL in vivo. The morphological characters of PCL/PTMC blend scaffold materials were investigated by scanning electron microscope (SEM). The molecular components and some physical characteristics of the blend scaffold materials were tested by FT-IR and DSC analysis.

Vascular tissue engineering and vascularized 3D tissue regeneration

2007 ◽  
Vol 2 (5) ◽  
pp. 831-837 ◽  
Author(s):  
Rei Ogawa ◽  
Koichiro Oki ◽  
Hike Hyakusoku
Keyword(s):  
Tissue Engineering ◽  
Tissue Regeneration ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering

Hydrogel Complex Electrospun Scaffolds and Their Multiple Functions in In Situ Vascular Tissue Engineering

2021 ◽  
Vol 4 (3) ◽  
pp. 2373-2384
Author(s):  
Xue Geng ◽  
Ze-Qin Xu ◽  
Cheng-Zhao Tu ◽  
Jia Peng ◽  
Xin Jin ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Multiple Functions ◽  
Electrospun Scaffolds

Vascular Tissue Regeneration of the Hybrid ePTFE Graft for Adult Patients

2005 ◽  
Vol 288-289 ◽  
pp. 55-58 ◽  
Author(s):  
In Sup Noh
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Tissue Regeneration ◽  
Vascular Graft ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Tissue Formation ◽  
High Demand ◽  
Eptfe Graft

Vascular Tissue engineering has drawn high interest due to its high demand in its vascular graft applications. We tissue-engineered a hybrid vascular graft consisting of tissues layers and non-biodegradable ePTFE by in vitro cell culture. Tissue formation was obtained by culturing vascular smooth muscle cells on the biodegradable polylactide scaffolds on the ePTFE surfaces. The fabricated hybrid ePTFE graft consisted of three layers, i.e. two biodegradable polylactide layers and a non-biodegradable ePTFE layer. The biodegradable layer was fabricated to have a porous structure with 30-60 µm pore sizes. Connection of biodegradable layers and ePTFE was obtained by filtering the polylactide solution through the porous ePTFE wall. For a better tissue formation coating of gelatin was performed on the luminal polylactide scaffolds. The generated tissues replaced the biodegradable layers on both inside and outside surfaces of the ePTFE.

Polymer-based Scaffold Designs For In Situ Vascular Tissue Engineering: Controlling Recruitment and Differentiation Behavior of Endothelial Colony Forming Cells

2012 ◽  
Vol 12 (5) ◽  
pp. 577-590 ◽  
Author(s):  
Emanuela S. Fioretta ◽  
Joost O. Fledderus ◽  
Ewelina A. Burakowska-Meise ◽  
Frank P. T. Baaijens ◽  
Marianne C. Verhaar ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Endothelial Colony Forming Cells

Air spun poly(lactic acid) nanofiber scaffold degradation for vascular tissue engineering: A 1H NMR study

2012 ◽  
Vol 97 (8) ◽  
pp. 1520-1526 ◽  
Author(s):  
Gad Sabbatier ◽  
Didier Le Nouën ◽  
Pascale Chevallier ◽  
Bernard Durand ◽  
Gaétan Laroche ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
1H Nmr ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Poly Lactic Acid ◽  
Nanofiber Scaffold ◽  
Nmr Study ◽  
Scaffold Degradation

Tailoring the Foreign Body Response for In Situ Vascular Tissue Engineering

2015 ◽  
Vol 21 (5) ◽  
pp. 436-446 ◽  
Author(s):  
Tonia C. Rothuizen ◽  
Febriyani F.R. Damanik ◽  
James M. Anderson ◽  
Tom Lavrijsen ◽  
Martijn A.J. Cox ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Foreign Body ◽  
Vascular Tissue ◽  
Foreign Body Response ◽  
Vascular Tissue Engineering ◽  
Body Response

Vascular tissue engineering: Biomechanical studies on autologeous small-calibred vessels

2006 ◽  
Vol 54 (S 1) ◽  
Author(s):  
K Kallenbach ◽  
J Heine ◽  
E Lefik ◽  
S Cebotari ◽  
A Lichtenberg ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering
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