scholarly journals Employing bicontinuous-to-micellar transitions in nanostructure morphology for on-demand photo-oxidation responsive cytosolic delivery and off–on cytotoxicity

Nanoscale ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 5332-5340 ◽  
Author(s):  
Sharan Bobbala ◽  
Sean D. Allen ◽  
Sijia Yi ◽  
Michael Vincent ◽  
Molly Frey ◽  
...  

PEG-b-PPS bicontinuous nanospheres resist degradation and stably retain payloads within cells. When loaded with a photosensitizing agent, these nanospheres demonstrate off–on inducible photo-responsive release of cytotoxic agents into the cytosol of cells.

2008 ◽  
Author(s):  
Jamie Chamberlin
Keyword(s):  

2001 ◽  
Vol 28 (4) ◽  
pp. 344-358 ◽  
Author(s):  
Harold J. Burstein ◽  
Craig A. Bunnell ◽  
Eric P. Winer

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
LA Giddings ◽  
S Shipley ◽  
T DeLloyd ◽  
DJ Newman

2009 ◽  
Vol 29 (S 01) ◽  
pp. S16-S18 ◽  
Author(s):  
B. Brand ◽  
N. von der Weid

SummaryThe Swiss Haemophilia Registry of the Medical Committee of the Swiss Haemophilia Society was established in 2000. Primarily it bears epidemiological and basic clinical data (incidence, type and severity of the disease, age groups, centres, mortality). Two thirds of the questions of the WFH Global Survey can be answered, especially those concerning use of concentrates (global, per capita) and treatment modalities (on-demand versus prophylactic regimens). Moreover, the registry is an important tool for quality control of the haemophilia treatment centres.There are no informations about infectious diseases like hepatitis or HIV, due to non-anonymisation of the data. We plan to incorporate the results of the mutation analysis in the future.


1978 ◽  
Vol 17 (04) ◽  
pp. 261-272 ◽  
Author(s):  
Y. Brault ◽  
G. Atlan ◽  
H. Lorino ◽  
A. Harf ◽  
A.-M. Lorino ◽  
...  

A system was built up around a minicomputer to process in real time pressure and flow signals collected during the course of three ventilatory mechanics tests: the calculation of the lung volume, the evaluation of the static lung compliance, the analysis of the forced expiratory performance. The subject is seated in an open body Plethysmograph, which allows for the instantaneous calculation of changes in the volume of his thorax and abdomen. The system is controlled through a graphics console which displays the sampled curves and the results of data processing. In addition, the signals can be stored on demand onto a magnetic tape so that the method can be tested and improved off line. The results obtained in healthy volunteers are highly reproducible. A close correspondence is found both in patients and volunteers between computer-derived and hand-calculated results. The computerized system has become a standard equipment of our Lung Function Department, where it allows for a rapid quantitative analysis of lung volumes, lung elasticity and bronchial airflow.


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