scholarly journals Quaternized styryl-azinium fluorophores as cellular RNA-binders

2020 ◽  
Vol 19 (3) ◽  
pp. 362-370
Author(s):  
Valentina Botti ◽  
Lorena Urbanelli ◽  
Krizia Sagini ◽  
Luigi Tarpani ◽  
Alessio Cesaretti ◽  
...  

Small dyes’ micromolar cytotoxicity, efficient dsRNA-binding and highly selective nucleolar localisation marked by strong fluorescence enhancement: potential theragnostics applications.

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3102 ◽  
Author(s):  
Bin Li ◽  
Datong Zhang ◽  
Ruibing An ◽  
Yaling Zhu

In this work, a novel 7-hydroxybenzoxazinone-based fluorescent probe (PBD) for the selective sensing of biothiols is reported. Upon treatment with biothiols, PBD shows a strong fluorescence enhancement (up to 70-fold) and a large Stokes shift (155 nm). Meanwhile, this probe exhibits high resistance to interference from other amino acids and competing species. PBD features good linearity ranges with a low detection limit of 14.5 nM for glutathione (GSH), 17.5 nM for cysteine (Cys), and 80.0 nM for homocysteine (Hcy), respectively. Finally, the potential utility of this probe for biothiol sensing in living HeLa cells is demonstrated.


Plasmonics ◽  
2016 ◽  
Vol 12 (2) ◽  
pp. 263-269 ◽  
Author(s):  
Yunran Zhai ◽  
Lingyan Meng ◽  
Lijun Xu ◽  
Lin Yuan ◽  
Zhilin Yang ◽  
...  

2002 ◽  
pp. 776-777 ◽  
Author(s):  
Başak Kükrer Kaletaş ◽  
René M. Williams ◽  
Burkhard König ◽  
Luisa De Cola

2015 ◽  
Vol 39 (1) ◽  
pp. 77-80 ◽  
Author(s):  
Jin-Lei Yang ◽  
Shuo-Hui Cao ◽  
Qian Liu ◽  
Shuang Zhao ◽  
Yu-Bin Zheng ◽  
...  

Up to 200 times fluorescence enhancement was observed inside a tapered silver-plated sub-wavelength pore.


2018 ◽  
Vol 42 (10) ◽  
pp. 8145-8150 ◽  
Author(s):  
A. Omerzu ◽  
I. Turel

Zinc–nucleotide complexes in alkaline solutions exhibit strong fluorescence enhancement and red shift, thus enabling an optical discrimination between the nucleotides.


AIP Advances ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. 025219 ◽  
Author(s):  
Feng Shan ◽  
Dan Su ◽  
Wei Li ◽  
Wei Hu ◽  
Tong Zhang

2016 ◽  
Vol 94 (7) ◽  
pp. 599-603 ◽  
Author(s):  
Dmitry S. Kopchuk ◽  
Dmitry E. Pavlyuk ◽  
Igor S. Kovalev ◽  
Grigory V. Zyryanov ◽  
Vladimir L. Rusinov ◽  
...  

A new ditopic ligand based on diethylenetriamine-N,N,N″,N″-tetraacetate (DTTA) and 5-phenyl-2,2′-bipyridine has been synthesized. The improved method for the synthesis of DTTA tert-butyl ester has been developed. The water-soluble Eu3+*DTTA complex of this ligand has been prepared, and its photophysical properties have been studied. Due to the presence of an extra chelating unit, 5-phenyl-2,2′-bipyridine, this Eu3+*DTTA complex demonstrated a strong fluorescence response to the Zn2+ cation (fluorescence enhancement) and the simultaneous fluorescent and phosphorescent response (fluorescence and phosphorescence quenching) to the Cu2+ or Ni2+ cations in aqueous solutions.


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