Synthesis and biological evaluation of a bioinspired, tissue-adhesive gellan gum-based hydrogel designed for minimally invasive delivery and retention of chondrogenic cells

2020 ◽  
Vol 8 (13) ◽  
pp. 3697-3711
Author(s):  
David A. Learmonth ◽  
Pedro M. Costa ◽  
Tiago R. Veloso ◽  
Cristiana B. Cunha ◽  
Mafalda P. Cautela ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Cartilage Regeneration ◽  
Biological Evaluation ◽  
Gellan Gum ◽  
Tissue Adhesive ◽  
Cell Delivery ◽  
Synthesis And Biological Evaluation ◽  
Invasive Cell

STM-148B, a bioinspired gellan gum hydrogel designed for minimally invasive cell delivery and retention in the context of cartilage regeneration.

scholarly journals ‘Surface Transplantation’ for Nerve Injury and Repair: The Quest for Minimally Invasive Cell Delivery

2018 ◽  
Vol 41 (7) ◽  
pp. 429-441
Author(s):  
Tetsuji Sekiya ◽  
Matthew C. Holley
Keyword(s):  
Minimally Invasive ◽  
Nerve Injury ◽  
Cell Delivery ◽  
Injury And Repair ◽  
Invasive Cell

Tissue Reconstruction: Tissue Adhesive Catechol-Modified Hyaluronic Acid Hydrogel for Effective, Minimally Invasive Cell Therapy (Adv. Funct. Mater. 25/2015)

2015 ◽  
Vol 25 (25) ◽  
pp. 3798-3798 ◽  
Author(s):  
Jisoo Shin ◽  
Jung Seung Lee ◽  
Changhyun Lee ◽  
Hyun-Ji Park ◽  
Kisuk Yang ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Cell Therapy ◽  
Minimally Invasive ◽  
Tissue Adhesive ◽  
Tissue Reconstruction ◽  
Hyaluronic Acid Hydrogel ◽  
Invasive Cell

Tissue Adhesive Catechol-Modified Hyaluronic Acid Hydrogel for Effective, Minimally Invasive Cell Therapy

2015 ◽  
Vol 25 (25) ◽  
pp. 3814-3824 ◽  
Author(s):  
Jisoo Shin ◽  
Jung Seung Lee ◽  
Changhyun Lee ◽  
Hyun-Ji Park ◽  
Kisuk Yang ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Cell Therapy ◽  
Minimally Invasive ◽  
Tissue Adhesive ◽  
Hyaluronic Acid Hydrogel ◽  
Invasive Cell

Synthesis and Biological Evaluation of New Salvinorin B-Sulfonate Ester Ligands to Opioid Receptors

Planta Medica ◽  
2013 ◽  
Vol 79 (05) ◽  
Author(s):  
PR Polepally ◽  
BL Roth ◽  
K White ◽  
E Vardy ◽  
JK Zjawiony
Keyword(s):  
Opioid Receptors ◽  
Biological Evaluation ◽  
Sulfonate Ester ◽  
Synthesis And Biological Evaluation

Harnessing the main event of drimentines biosynthesis: bio-inspired synthesis and biological evaluation of Δ8'-isodrimentine A and related compounds

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
A Skiredj ◽  
MA Beniddir ◽  
L Evanno ◽  
E Poupon
Keyword(s):  
Biological Evaluation ◽  
Synthesis And Biological Evaluation ◽  
Related Compounds

Synthesis and Biological Evaluation of the Antimicrobial Natural Product Lipoxazolidinone A

2018 ◽  
Author(s):  
Jonathan J. Mills ◽  
Kaylib R. Robinson ◽  
Troy E. Zehnder ◽  
Joshua G. Pierce
Keyword(s):  
Natural Products ◽  
Natural Product ◽  
Mechanism Of Action ◽  
Marine Natural Products ◽  
Biological Evaluation ◽  
Lead Compounds ◽  
Follow Up Studies ◽  
Initial Resistance ◽  
Synthesis And Biological Evaluation

The lipoxazolidinone family of marine natural products, with an unusual 4-oxazolidinone heterocycle at their core, represents a new scaffold for antimicrobial discovery; however, questions regarding their mechanism of action and high lipophilicity have likely slowed follow-up studies. Herein, we report the first synthesis of lipoxazolidinone A, 15 structural analogs to explore its active pharmacophore, and initial resistance and mechanism of action studies. These results suggest that 4-oxazolidinones are valuable scaffolds for antimicrobial development and reveal simplified lead compounds for further optimization.

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