Synthesis and Biological Evaluation of Metal Complexes

2018 ◽  
Vol 8 (2) ◽  
Keyword(s):  
Metal Complexes ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of a novel ONS tridentate Schiff base bearing pyrimidine ring and some metal complexes

2014 ◽  
Vol 23 (7) ◽  
pp. 3451-3457 ◽  
Author(s):  
Mehmet Sönmez ◽  
Hatice Gamze Sogukomerogullari ◽  
Feyza Öztemel ◽  
İsmet Berber
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Pyrimidine Ring ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation ◽  
Tridentate Schiff Base

scholarly journals Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes againstMycobacterium tuberculosis

2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Mustapha C. Mandewale ◽  
Bapu Thorat ◽  
Dnyaneshwar Shelke ◽  
Ramesh Yamgar
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Metal Complexes ◽  
Inhibitory Activity ◽  
Biological Properties ◽  
Biological Evaluation ◽  
Fluorescence Properties ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated againstMycobacterium tuberculosis(H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25–25 μg/mL, againstMycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied.

Synthesis and biological evaluation of heterocyclic hydrazone transition metal complexes as potential anticancer agents

RSC Advances ◽  
2016 ◽  
Vol 6 (111) ◽  
pp. 109718-109725 ◽  
Author(s):  
Yunpeng Du ◽  
Wei Chen ◽  
Xiang Fu ◽  
Hang Deng ◽  
JunGang Deng
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Anticancer Agents ◽  
Biological Evaluation ◽  
Intracellular Ros ◽  
Synthesis And Biological Evaluation

Only the [Cu(L)2] complex can significantly increase the intracellular ROS levels, leading to relatively high antiproliferative potency.

Design, synthesis and biological evaluation of novel estrogen-derived steroid metal complexes

2013 ◽  
Vol 23 (13) ◽  
pp. 3793-3797 ◽  
Author(s):  
Xinlong Zhang ◽  
Ziqing Zuo ◽  
Juan Tang ◽  
Kai Wang ◽  
Caihua Wang ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Half-sandwich platinum group metal complexes containing coumarin-N-acylhydrazone hybrid ligands: Synthesis and biological evaluation studies

2021 ◽  
pp. 120459
Author(s):  
Carley Giffert L Nongpiur ◽  
Lincoln Dkhar ◽  
Deepak Kumar Tripathi ◽  
Krishna Mohan Poluri ◽  
Werner Kaminsky ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Evaluation Studies ◽  
Platinum Group Metal ◽  
Biological Evaluation ◽  
Group Metal ◽  
Platinum Group ◽  
Hybrid Ligands ◽  
Synthesis And Biological Evaluation ◽  
Half Sandwich

scholarly journals Synthesis and Biological Evaluation Study of New Bis-imine Ligand and Metal Complexes

2020 ◽  
Vol 10 (2) ◽  
pp. 2207-2214
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Evaluation Study ◽  
Antimicrobial Activities ◽  
Biological Evaluation ◽  
Spectroscopic Techniques ◽  
Metal Ratio ◽  
Synthesis And Biological Evaluation

A new Schiff base bis-imine ligand was synthesized by the reaction of 1-(2-bromo, 5-methoxy benzylidene) hydrazine and 5-chlorosalicylaldehyde. This bis-imine ligand was used for the synthesis of metal complexes. The synthesized ligand and metal complexes were characterized by spectroscopic techniques. The metal complexes were formed in the ligand to metal ratio of 2:1. The synthesized metal complexes were screened for antimalarial, anti-tubercular, and antimicrobial activities.

scholarly journals Complexes of Pyrimidine Thiones: Mechanochemical Synthesis and Biological Evaluation

2020 ◽  
Vol 32 (10) ◽  
pp. 2594-2600
Author(s):  
Pooja Sethi ◽  
Rajshree Khare ◽  
Renuka Choudhary
Keyword(s):  
Magnetic Susceptibility ◽  
Thermogravimetric Analysis ◽  
Metal Complexes ◽  
Mechanochemical Synthesis ◽  
Far Infrared ◽  
Biological Evaluation ◽  
Spectral Moment ◽  
Mass Spectral ◽  
Infrared Spectral ◽  
Synthesis And Biological Evaluation

A new series of metal complexes with 1-(2-methylphenyl)-4,4,6-trimethyl pyrimidine-2-thione (2-HL1) and 1-(4-methylphenyl)-4,4,6-trimethyl pyrimidine-2-thione (4-HL2) ligands, [M(mppt)2(H2O)n] (M(II) = Cu, Mn, Co; n = 2 and M(II) = Ni, Zn; n = 0) have been synthesized using mechanochemical protocol. The complexes have been framed as [M(mppt)2(H2O)n] due to 1:2 (metal:ligand) nature of these metal complexs. Structures have been further confirmed on the basis of elemental analysis, Magnetic susceptibility measurements, electronic, infrared, far infrared, proton NMR, Mass spectral moment and thermogravimetric analysis studies. The infrared spectral data suggested that ligand behaves as a bidentate, coordinating through – N (endocyclic) and – S (exocyclic) donor atoms. All the compounds have also been screened for antibacterial and DNA photocleavage potential. Ligands complexed with Mn and Ni metals have shown the effect of substitution on their biological potentials. It was found that substitution at 4th or para position makes the ligand and its metal complexes have better antibacterial and DNA photocleaving agents.

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