Effective intracellular delivery of bevacizumab via PEGylated polymeric nanoparticles targeting the CD44v6 receptor in colon cancer cells

2020 ◽  
Vol 8 (13) ◽  
pp. 3720-3729
Author(s):  
Ana Baião ◽  
Flávia Sousa ◽  
Ana Vanessa Oliveira ◽  
Carla Oliveira ◽  
Bruno Sarmento
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Polymeric Nanoparticles ◽  
Intracellular Delivery ◽  
Colon Cancer Cells

v6 Fab-PLGA-PEG NPs have the potential to deliver intracellularly bevacizumab in CD44v6 expressing cancer cells.

pH- and GSH-Sensitive Hyaluronic Acid-MP Conjugate Micelles for Intracellular Delivery of Doxorubicin to Colon Cancer Cells and Cancer Stem Cells

2018 ◽  
Vol 19 (9) ◽  
pp. 3725-3737 ◽  
Author(s):  
Tilahun Ayane Debele ◽  
Lu-Yi Yu ◽  
Cheng-Sheng Yang ◽  
Yao-An Shen ◽  
Chun-Liang Lo
Keyword(s):  
Stem Cells ◽  
Colon Cancer ◽  
Hyaluronic Acid ◽  
Cancer Stem Cells ◽  
Cancer Cells ◽  
Intracellular Delivery ◽  
Colon Cancer Cells

scholarly journals Co-delivery of camptothecin and curcumin by cationic polymeric nanoparticles for synergistic colon cancer combination chemotherapy

2015 ◽  
Vol 3 (39) ◽  
pp. 7724-7733 ◽  
Author(s):  
Bo Xiao ◽  
Xiaoying Si ◽  
Moon Kwon Han ◽  
Emilie Viennois ◽  
Mingzhen Zhang ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Combination Chemotherapy ◽  
Polymeric Nanoparticles ◽  
Synergistic Effects ◽  
Colon Cancer Cells

Camptothecin (CPT) and curcumin (CUR) have been co-loaded into cationic polymeric nanoparticles and exhibited strong synergistic effects against colon cancer cells.

Leptin is a growth factor for human colon cancer cells

2001 ◽  
Vol 120 (5) ◽  
pp. A493-A493
Author(s):  
J HARDWICK ◽  
G VANDENBRINK ◽  
S VANDEVENTER ◽  
M PEPPELENBOSCH
Keyword(s):  
Colon Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

Silencing of a death associated protein kinase as a pro-survival factor in colon cancer cells

Endoscopy ◽  
2005 ◽  
Vol 37 (05) ◽  
Author(s):  
GA Doherty ◽  
SM Byrne ◽  
SC Austin ◽  
GM Scully ◽  
EW Kay ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Protein Kinase ◽  
Cancer Cells ◽  
Colon Cancer Cells ◽  
Survival Factor ◽  
Death Associated Protein Kinase
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