Hydrophobically modified carbon dots as a multifunctional platform for serum-resistant gene delivery and cell imaging

2020 ◽  
Vol 8 (13) ◽  
pp. 3730-3740
Author(s):  
Ping Chen ◽  
Ji Zhang ◽  
Xi He ◽  
Yan-Hong Liu ◽  
Xiao-Qi Yu
Keyword(s):  
Gene Delivery ◽  
Carbon Dots ◽  
Cell Imaging ◽  
Activity Relationship ◽  
Viral Gene ◽  
Resistant Gene ◽  
Hydrophobically Modified ◽  
Structure Activity ◽  
Gene Vectors ◽  
Multifunctional Platform

Hydrophobically modified carbon dots were prepared and their structure-activity relationship as non-viral gene vectors was investigated.

Structure–activity relationship studies of symmetrical cationic bolasomes as non-viral gene vectors

2016 ◽  
Vol 4 (33) ◽  
pp. 5575-5584 ◽  
Author(s):  
Zheng Huang ◽  
Yi-Mei Zhang ◽  
Qian Cheng ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Viral Gene ◽  
Structure Activity ◽  
Gene Delivery Vectors ◽  
Gene Vectors

Bolalipids based on lysine or cyclen headgroups were synthesized and their structure–activity relationship as gene delivery vectors was studied.

scholarly journals Cationic lipids with a cyclen headgroup: synthesis and structure–activity relationship studies as non-viral gene vectors

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18681-18689 ◽  
Author(s):  
De-Chun Chang ◽  
Yi-Mei Zhang ◽  
Ji Zhang ◽  
Yan-Hong Liu ◽  
Xiao-Qi Yu
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Cationic Lipids ◽  
Activity Relationship ◽  
Viral Gene ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Gene Delivery Vectors ◽  
Gene Vectors ◽  
Viral Gene Delivery

The structure–activity relationships of cyclen-based cationic lipids as non-viral gene delivery vectors were studied and clarified.

Cationic gemini lipids with cyclen headgroups: interaction with DNA and gene delivery abilities

RSC Advances ◽  
2014 ◽  
Vol 4 (83) ◽  
pp. 44261-44268 ◽  
Author(s):  
Yi-Mei Zhang ◽  
Yan-Hong Liu ◽  
Ji Zhang ◽  
Qiang Liu ◽  
Zheng Huang ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Cationic Lipids ◽  
Activity Relationship ◽  
Viral Gene ◽  
Structure Activity ◽  
Gene Vectors

Eleven Gemini cationic lipids and one mono counterpart were synthesized, and their structure–activity relationship as non-viral gene vectors was studied.

Structure–activity relationship of novel low-generation dendrimers for gene delivery

2018 ◽  
Vol 16 (42) ◽  
pp. 7833-7842 ◽  
Author(s):  
Yong-Guang Gao ◽  
Xiao Lin ◽  
Kai Dang ◽  
Shan-Feng Jiang ◽  
Ye Tian ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Sar Studies ◽  
Structure Activity ◽  
Gene Vectors ◽  
Relationship Of

Structure–activity relationship (SAR) studies are very critical to design ideal gene vectors for gene delivery.

Polycation-b-Polyzwitterion Copolymer Grafted Luminescent Carbon Dots As a Multifunctional Platform for Serum-Resistant Gene Delivery and Bioimaging

2014 ◽  
Vol 6 (22) ◽  
pp. 20487-20497 ◽  
Author(s):  
Lu Cheng ◽  
Yongmao Li ◽  
Xinyun Zhai ◽  
Bing Xu ◽  
Zhiqiang Cao ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Carbon Dots ◽  
Resistant Gene ◽  
Multifunctional Platform

Cationic polymer-derived carbon dots for enhanced gene delivery and cell imaging

2019 ◽  
Vol 7 (5) ◽  
pp. 1940-1948 ◽  
Author(s):  
Xi He ◽  
Ping Chen ◽  
Ji Zhang ◽  
Tian-Ying Luo ◽  
Hai-Jiao Wang ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Carbon Dots ◽  
Ring Opening ◽  
Cell Imaging ◽  
High Efficiency ◽  
Ring Opening Polymerization ◽  
Cationic Polymer ◽  
Cationic Polymers ◽  
Promising Strategy ◽  
Gene Vectors

The transformation of cationic polymers derived from ring-opening polymerization to carbon dots was proved as a promising strategy for developing gene vectors with high efficiency and cell-imaging ability.

scholarly journals Structure–Activity Relationship of PEGylated Polylysine Peptides as Scavenger Receptor Inhibitors for Non-Viral Gene Delivery

2015 ◽  
Vol 12 (12) ◽  
pp. 4321-4328 ◽  
Author(s):  
Nicholas J. Baumhover ◽  
Jason T. Duskey ◽  
Sanjib Khargharia ◽  
Christopher W. White ◽  
Samuel T. Crowley ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Scavenger Receptor ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Viral Gene ◽  
Structure Activity ◽  
Viral Gene Delivery ◽  
Relationship Of

Flexible cyclic siloxane core enhances the transfection efficiency of polyethylenimine-based non-viral gene vectors

2015 ◽  
Vol 3 (42) ◽  
pp. 8250-8267 ◽  
Author(s):  
Cristina M. Uritu ◽  
Manuela Calin ◽  
Stelian S. Maier ◽  
Corneliu Cojocaru ◽  
Alina Nicolescu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Transfection Efficiency ◽  
Viral Gene ◽  
Cyclic Siloxane ◽  
Gene Vectors

cD4H–AGE–PEI conjugates, with a favorable balance between hydrophilic and hydrophobic moieties, are promising carriers for gene delivery.

scholarly journals Photoluminescent F-doped carbon dots prepared by ring-opening reaction for gene delivery and cell imaging

RSC Advances ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 6053-6062 ◽  
Author(s):  
Tian-Ying Luo ◽  
Xi He ◽  
Ji Zhang ◽  
Ping Chen ◽  
Yan-Hong Liu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gene Delivery ◽  
Carbon Dots ◽  
Ring Opening ◽  
Cell Imaging ◽  
Imaging Agents ◽  
Ring Opening Reaction ◽  
Doped Carbon Dots

Carbon dots (CDs) are photoluminescent nanoparticles with distinctive properties, having great potential in nano-biomaterial systems such as gene/drug delivery vectors and cell imaging agents.

scholarly journals A new structure–activity relationship for cyanine dyes to improve photostability and fluorescence properties for live cell imaging

2018 ◽  
Vol 9 (31) ◽  
pp. 6557-6563 ◽  
Author(s):  
Christian Schwechheimer ◽  
Franziska Rönicke ◽  
Ute Schepers ◽  
Hans-Achim Wagenknecht
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Cyanine Dyes ◽  
Structure Activity Relationship ◽  
Live Cell ◽  
Fluorescence Properties ◽  
Activity Relationship ◽  
Structure Activity

A new set of cyanine-indole dyes was synthesized, characterized by optical and cytotoxic properties and subsequently applied for live cell imaging.

Sign in / Sign up

Export Citation Format

Share Document