Physicochemical properties of polysaccharides from Ligusticum chuanxiong and analysis of their anti-tumor potential through immunoregulation

Topological index is a numerical representation of a chemical structure. Based on these indices, physicochemical properties, thermodynamic behavior, chemical reactivity, and biological activity of chemical compounds are calculated. Acetaminophen is an essential drug to prevent/treat various types of viral fever, including malaria, flu, dengue, SARS, and even COVID-19. This paper computes the sum and multiplicative version of various topological indices such as General Zagreb, General Randić, General OGA, AG, ISI, SDD, Forgotten indices M-polynomials of Acetaminophen. To the best of our knowledge, for the Acetaminophen drugs, these indices have not been computed previously.

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PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITY: THERMODYNAMIC PROPERTIES OF COMPOUNDS RELATED TO ACETYLCHOLINE ASSESSED FROM DEPRESSION OF FREEZING-POINT AND ENTHALPIES OF DILUTION

British Journal of Pharmacology ◽

10.1111/j.1476-5381.1974.tb10677.x ◽

1974 ◽

Vol 51 (3) ◽

pp. 413-426 ◽

Cited By ~ 3

Author(s):

R.B. BARLOW

Keyword(s):

Biological Activity ◽

Thermodynamic Properties ◽

Physicochemical Properties ◽

Freezing Point ◽

Enthalpies Of Dilution

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Characterization of physicochemical properties of nanomaterials and their immediate environments in high-throughput screening of nanomaterial biological activity

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology ◽

10.1002/wnan.1229 ◽

2013 ◽

Vol 5 (5) ◽

pp. 430-448 ◽

Cited By ~ 5

Author(s):

Amy Wang ◽

Stella M. Marinakos ◽

Appala Raju Badireddy ◽

Christina M. Powers ◽

Keith A. Houck

Keyword(s):

Biological Activity ◽

Physicochemical Properties ◽

High Throughput ◽

High Throughput Screening

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Low-energy nanoemulsions as carriers for red raspberry seed oil: Formulation approach based on Raman spectroscopy and textural analysis, physicochemical properties, stability and in vitro antioxidant/ biological activity

PLoS ONE ◽

10.1371/journal.pone.0230993 ◽

2020 ◽

Vol 15 (4) ◽

pp. e0230993

Author(s):

Ana Gledovic ◽

Aleksandra Janosevic Lezaic ◽

Veljko Krstonosic ◽

Jelena Djokovic ◽

Ines Nikolic ◽

...

Keyword(s):

Raman Spectroscopy ◽

Biological Activity ◽

Physicochemical Properties ◽

Seed Oil ◽

Textural Analysis ◽

Low Energy ◽

Red Raspberry ◽

Oil Formulation

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Characterization and influence of hydroxyapatite nanopowders on living cells

Beilstein Journal of Nanotechnology ◽

10.3762/bjnano.9.286 ◽

2018 ◽

Vol 9 ◽

pp. 3079-3094 ◽

Cited By ~ 17

Author(s):

Przemyslaw Oberbek ◽

Tomasz Bolek ◽

Adrian Chlanda ◽

Seishiro Hirano ◽

Sylwia Kusnieruk ◽

...

Keyword(s):

Particle Size ◽

Biological Activity ◽

Physicochemical Properties ◽

Living Cells ◽

Great Promise ◽

Medical Applications ◽

Synthesis Methods ◽

Hydroxyapatite Nanoparticles ◽

Manufacturing Methods ◽

The Impact

Nanomaterials, such as hydroxyapatite nanoparticles show a great promise for medical applications due to their unique properties at the nanoscale. However, there are concerns about the safety of using these materials in biological environments. Despite a great number of published studies of nanoobjects and their aggregates or agglomerates, the impact of their physicochemical properties (such as particle size, surface area, purity, details of structure and degree of agglomeration) on living cells is not yet fully understood. Significant differences in these properties, resulting from different manufacturing methods, are yet another problem to be taken into consideration. The aim of this work was to investigate the correlation between the properties of nanoscale hydroxyapatite from different synthesis methods and biological activity represented by the viability of four cell lines: A549, CHO, BEAS-2B and J774.1 to assess the influence of the nanoparticles on immune, reproductive and respiratory systems.

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