scholarly journals Near-infrared fluorescent molecular probes for imaging and diagnosis of nephro-urological diseases

2021 ◽  
Author(s):  
Jiaguo Huang ◽  
Kanyi Pu
Keyword(s):  
Near Infrared ◽  
Molecular Probes ◽  
Imaging Depth ◽  
Fluorescent Molecular Probes ◽  
Urological Diseases

Near-infrared fluorescent molecular probes with improved imaging depth and optimized biodistribution have been reviewed, showing great potential for diagnosis of nephro-urological diseases.

scholarly journals Sound Out the Deep Colors: Photoacoustic Molecular Imaging at New Depths

2020 ◽  
Vol 19 ◽  
pp. 153601212098151
Author(s):  
Mucong Li ◽  
Nikhila Nyayapathi ◽  
Hailey I. Kilian ◽  
Jun Xia ◽  
Jonathan F. Lovell ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Near Infrared ◽  
High Sensitivity ◽  
Biological Tissues ◽  
Molecular Probes ◽  
Cellular Processes ◽  
Reconstruction Methods ◽  
Recent Developments ◽  
Imaging Depth ◽  
Molecular Signals

Photoacoustic tomography (PAT) has become increasingly popular for molecular imaging due to its unique optical absorption contrast, high spatial resolution, deep imaging depth, and high imaging speed. Yet, the strong optical attenuation of biological tissues has traditionally prevented PAT from penetrating more than a few centimeters and limited its application for studying deeply seated targets. A variety of PAT technologies have been developed to extend the imaging depth, including employing deep-penetrating microwaves and X-ray photons as excitation sources, delivering the light to the inside of the organ, reshaping the light wavefront to better focus into scattering medium, as well as improving the sensitivity of ultrasonic transducers. At the same time, novel optical fluence mapping algorithms and image reconstruction methods have been developed to improve the quantitative accuracy of PAT, which is crucial to recover weak molecular signals at larger depths. The development of highly-absorbing near-infrared PA molecular probes has also flourished to provide high sensitivity and specificity in studying cellular processes. This review aims to introduce the recent developments in deep PA molecular imaging, including novel imaging systems, image processing methods and molecular probes, as well as their representative biomedical applications. Existing challenges and future directions are also discussed.

Ratiometric Analysis of Fluorescence Lifetime for Probing Binding Sites in Albumin with Near-Infrared Fluorescent Molecular Probes

2007 ◽  
Vol 83 (6) ◽  
pp. 1371-1378 ◽  
Author(s):  
Mikhail Y. Berezin ◽  
Hyeran Lee ◽  
Walter Akers ◽  
Gregory Nikiforovich ◽  
Samuel Achilefu
Keyword(s):  
Fluorescence Lifetime ◽  
Binding Sites ◽  
Near Infrared ◽  
Molecular Probes ◽  
Fluorescent Molecular Probes

scholarly journals Non-Covalently Pre-Assembled High-Performance Near-Infrared Fluorescent Molecular Probes for Cancer Imaging

2018 ◽  
Vol 24 (52) ◽  
pp. 13821-13829 ◽  
Author(s):  
Scott K. Shaw ◽  
Wenqi Liu ◽  
César Fernando Azael Gómez Durán ◽  
Cynthia L. Schreiber ◽  
María de Lourdes Betancourt Mendiola ◽  
...  
Keyword(s):  
High Performance ◽  
Near Infrared ◽  
Cancer Imaging ◽  
Molecular Probes ◽  
Fluorescent Molecular Probes

Fluorescent Molecular Probes II. The Synthesis, Spectral Properties and Use of Fluorescent Solvatochromic Dapoxyl Dyes

1997 ◽  
Vol 66 (4) ◽  
pp. 424-431 ◽  
Author(s):  
Zhenjun Diwu ◽  
Yixin Lu ◽  
Cailan Zhang ◽  
Dieter H. Klaubert ◽  
Richard P. Haugland
Keyword(s):  
Spectral Properties ◽  
Molecular Probes ◽  
Fluorescent Molecular Probes

Anti-Scarring Drug Screening with Near-Infrared Molecular Probes Targeting Fibroblast Activation Protein-α

2018 ◽  
Vol 1 (6) ◽  
pp. 2054-2061 ◽  
Author(s):  
David C. Yeo ◽  
Christian Wiraja ◽  
Qingqing Miao ◽  
Xiaoyu Ning ◽  
Kanyi Pu ◽  
...  
Keyword(s):  
Drug Screening ◽  
Near Infrared ◽  
Fibroblast Activation Protein ◽  
Molecular Probes ◽  
Fibroblast Activation

scholarly journals Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes

2018 ◽  
Vol 11 (4) ◽  
pp. e201700232 ◽  
Author(s):  
Jessica Miller ◽  
Steven T. Wang ◽  
Inema Orukari ◽  
Julie Prior ◽  
Gail Sudlow ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Near Infrared ◽  
Molecular Probes ◽  
Imaging Method

ChemInform Abstract: Enzymatic Synthesis of 8-Vinyl- and 8-Styryl-2′-deoxyguanosine Modified DNA - Novel Fluorescent Molecular Probes.

ChemInform ◽  
2012 ◽  
Vol 43 (39) ◽  
pp. no-no
Author(s):  
Bastian Holzberger ◽  
Julian Strohmeier ◽  
Vanessa Siegmund ◽  
Ulf Diederichsen ◽  
Andreas Marx
Keyword(s):  
Enzymatic Synthesis ◽  
Molecular Probes ◽  
Modified Dna ◽  
Fluorescent Molecular Probes

Development and sensing applications of fluorescent motifs within the mitochondrial environment

2015 ◽  
Vol 51 (86) ◽  
pp. 15614-15628 ◽  
Author(s):  
Roopa Roopa ◽  
Naresh Kumar ◽  
Vandana Bhalla ◽  
Manoj Kumar
Keyword(s):  
Molecular Probes ◽  
Sensing Applications ◽  
Fluorescent Molecular Probes

In this article, our objective is to discuss fluorescent molecular probes that have been designed with their sensing applications within the mitochondrial environment.

Sign in / Sign up

Export Citation Format

Share Document