Molecular Mechanism of Amyloidogenicity and Neurotoxicity of a Pro-aggregated Tau Mutant in the Presence of Histidine Tautomerism via Replica-Exchange Simulation.

2021 ◽  
Author(s):  
Sompriya Chatterjee ◽  
Abbas Salimi ◽  
Jin Yong Lee
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Molecular Mechanism ◽  
Replica Exchange

The accumulation of ΔK280 tau mutant resulting in neurotoxic oligomeric aggregates is an important but yet mysterious procedure in Alzheimer’s disease (AD) development. Recently, we proposed a histidine tautomerization hypothesis...

P4-129: Alzheimer's disease: Molecular mechanism of anesthetics induced ABETA peptide oligomerization using spectroscopy

2006 ◽  
Vol 2 ◽  
pp. S553-S554
Author(s):  
Pravat K. Mandal ◽  
Jay W. Pettegrew ◽  
K. Panchalingam ◽  
Ratna Mandal
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Molecular Mechanism ◽  
Abeta Peptide

A comparative study of EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine on Aβ42 induced cognitive deficiency in a rat model of Alzheimer's disease

2018 ◽  
Vol 9 (5) ◽  
pp. 3008-3017 ◽  
Author(s):  
Hongxia Che ◽  
Qian Li ◽  
Tiantian Zhang ◽  
Lin Ding ◽  
Lingyu Zhang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Comparative Study ◽  
Molecular Mechanism ◽  
Rat Model ◽  
Model Of Alzheimer’S Disease ◽  
Ethanolamine Plasmalogen ◽  
Cognitive Deficiency

The possible molecular mechanism of EPA-pPE and EPA-PE on AD.

P1-191 Blocking the initial molecular mechanism of Alzheimer's disease

2004 ◽  
Vol 25 ◽  
pp. S150
Author(s):  
Vernon M. Ingram ◽  
Barbara J. Blanchard ◽  
Albert Chen ◽  
Crystle Kelly ◽  
Kate A. Stafford ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Molecular Mechanism
Sign in / Sign up

Export Citation Format

Share Document