Elucidating Microscopic Events Driven by GTP Hydrolysis Reaction in Ras-GAP System with Semi-reactive Molecular Dynamics Simulation: Alternative Role of Phosphate Binding Loop as Mechanical Energy Storage
Keyword(s):
ATPase and GTPase have been widely found as chemical energy-mechanical work transducers, whereas the physicochemical mechanisms are not satisfactorily understood. We addressed the problem by examining John Ross’ conjecture that...
2017 ◽
Vol 42
(15)
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pp. 9667-9678
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2014 ◽
Vol 109
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pp. 101-108
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2013 ◽
Vol 46
(42)
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pp. 425302
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