Exploring the Entropy-Driven Amplification Reaction and Trans-Cleavage Activity of CRISPR-Cas12a for the Development of an Electrochemiluminescence Biosensor for the Detection of SARS-CoV-2 RdRp Gene in Real Samples and Environmental Surveillance

Author(s):  
Kai Zhang ◽  
Zhenqiang Fan ◽  
Sha Zhu ◽  
Yuedi Ding ◽  
Minhao Xie ◽  
...  

In this paper, we present the first idea of using a DNA triple helix structure to inhibit CRISPR-Cas12a activity and apply it to the design of an electrochemiluminescent biosensor for...

Biochemistry ◽  
2008 ◽  
Vol 47 (18) ◽  
pp. 5068-5077 ◽  
Author(s):  
Yuliang Wu ◽  
Nina Rawtani ◽  
Arun Kalliat Thazhathveetil ◽  
Mark K. Kenny ◽  
Michael M. Seidman ◽  
...  

FEBS Letters ◽  
1991 ◽  
Vol 284 (2) ◽  
pp. 232-234 ◽  
Author(s):  
Nina G. Dolinnaya ◽  
Olga V. Pyatrauskene ◽  
Zoe A. Shabarova

2021 ◽  
Vol 350 ◽  
pp. 129261
Author(s):  
Xiaolong Yang ◽  
Siqing Wei ◽  
Xiaoming Lu ◽  
Xuguang Qiao ◽  
Jesus Simal-Gandara ◽  
...  

1990 ◽  
Vol 18 (1) ◽  
pp. 157-161 ◽  
Author(s):  
Jeffery C. Hanvey ◽  
Mitsuhiro Shimizu ◽  
Robert D. Wells

1997 ◽  
pp. 1561-1562 ◽  
Author(s):  
Vincent A. Grillo ◽  
Elisa J. Seddon ◽  
Craig M. Grant ◽  
Guillem Aromí ◽  
John C. Bollinger ◽  
...  

Biochemistry ◽  
2001 ◽  
Vol 40 (37) ◽  
pp. 11065-11072 ◽  
Author(s):  
Stephen W. Powell ◽  
Lihong Jiang ◽  
Irina M. Russu

2012 ◽  
pp. 535-565
Author(s):  
Elias Carayannis ◽  
David F.J. Campbell

This article develops an inter-disciplinary and trans-disciplinary framework of analysis that relates knowledge, innovation and the environment (natural environments) to each other. For that purpose the five-helix structure model of the Quintuple Helix is being introduced. The Triple Helix model, designed by Etzkowitz and Leydesdorff (2000), focuses on the relations of universities, industry and governments. The Quadruple Helix (Carayannis & Campbell, 2009) blends in the perspective of a media-based and culture-based public. The Quintuple Helix finally frames knowledge and innovation in the context of the environment (natural environments). Therefore, the Quintuple Helix can be interpreted as an approach in line with sustainable development and social ecology. “Eco-innovation” and “eco-entrepreneurship” should be processed in such a broader understanding of knowledge and innovation.


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