A gastro-resistant peptide from Momordica charantia improves diabetic nephropathy in db/db mice via its novel reno-protective and anti-inflammatory activities

2022 ◽  
Author(s):  
Pei-Yung Liao ◽  
Hsin-Yi Lo ◽  
I-Chen Liu ◽  
Lun-Chien Lo ◽  
Chien-Yun Hsiang ◽  
...  

Diabetic nephropathy (DN), a principal diabetic microvascular complication, is a chronic inflammatory immune disorder. A gastro-resistant peptide mcIRBP-9 from Momordica charantia has shown the modulation of blood glucose homeostasis in...

2022 ◽  
Author(s):  
Pei-Yung Liao ◽  
Hsin-Yi Lo ◽  
I-Chen Liu ◽  
Lun-Chien Lo ◽  
Chien-Yun Hsiang ◽  
...  

Diabetic nephropathy is an inflammatory immune disorder accompanying diabetes. mcIRBP, the trypsin inhibitor of Momordica charantia, is an abundant 68-amino-acid-residue protein that interacts with the insulin receptor. Here the long-term...


2011 ◽  
Vol 141 (3) ◽  
pp. 950-958 ◽  
Author(s):  
Adam P. Chambers ◽  
Lene Jessen ◽  
Karen K. Ryan ◽  
Stephanie Sisley ◽  
Hilary E. Wilson–Pérez ◽  
...  

Metabolism ◽  
1976 ◽  
Vol 25 (11) ◽  
pp. 1381-1383 ◽  
Author(s):  
Robert Sherwin ◽  
John Wahren ◽  
Philip Felig

1993 ◽  
Vol 3 (3) ◽  
pp. 167-171 ◽  
Author(s):  
L.G. WELBORN ◽  
J.M. NORDEN ◽  
N. SEIDEN ◽  
R.S. HANNALLAH ◽  
R.I. PATEL ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document