Engineering WS2-Au-HRP assisted-multiple signal amplification strategy for chemiluminescence immunoassay of prostate specific antigen

2021 ◽  
Author(s):  
Juntao Cao ◽  
Li-Zhen Zhao ◽  
Wen-Sheng Zhang ◽  
Shu-Hui Ma ◽  
Yan-Ming Liu
Keyword(s):  
Gold Nanoparticles ◽  
Horseradish Peroxidase ◽  
Prostate Specific Antigen ◽  
Signal Amplification ◽  
Specific Antigen ◽  
Tungsten Disulfide ◽  
Chemiluminescence Immunoassay ◽  
Au Nps ◽  
Multiple Signal ◽  
Amplification Strategy

A novel chemiluminescence (CL) immunosensor using functionalized Tungsten disulfide nanosheets (WS2 NSs)-gold nanoparticles (Au NPs)-horseradish peroxidase (WS2-Au-HRP) as multiple signal amplification probe was developed for prostate specific antigen (PSA) analysis....

An electrochemical immunosensor based on a multiple signal amplification strategy for highly sensitive detection of prostate specific antigen

2018 ◽  
Vol 10 (40) ◽  
pp. 4917-4925 ◽  
Author(s):  
Li Liu ◽  
Guanhui Zhao ◽  
Xue Dong ◽  
Xuan Li ◽  
Qin Wei ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Signal Amplification ◽  
Specific Antigen ◽  
Electrochemical Immunosensor ◽  
Sensitive Detection ◽  
Multiple Signal ◽  
Highly Sensitive ◽  
Sandwich Type ◽  
Highly Sensitive Detection ◽  
Amplification Strategy

A sandwich-type electrochemical immunosensor was developed based on a multiple signal amplification strategy.

An acid-responsive all-in-one signal amplification strategy for the ultrasensitive prostate-specific antigen detection

2019 ◽  
Vol 43 (40) ◽  
pp. 15910-15914 ◽  
Author(s):  
Yan Wang ◽  
Lijuan Chen ◽  
Qingxia Wu ◽  
Zejun Wen ◽  
Yujing Ren ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Signal Amplification ◽  
Specific Antigen ◽  
Antigen Detection ◽  
One Pot ◽  
Colorimetric Immunoassay ◽  
Amplification Strategy

A one-pot strategy for the preparation of all-in-one signal tags for the colorimetric immunoassay of prostate-specific antigen.

A dual-round signal amplification strategy for colorimetric/photoacoustic/fluorescence triple read-out detection of prostate specific antigen

2020 ◽  
Vol 56 (36) ◽  
pp. 4942-4945 ◽  
Author(s):  
Chao Jiang ◽  
Yan Huang ◽  
Ting He ◽  
Peng Huang ◽  
Jing Lin
Keyword(s):  
Prostate Specific Antigen ◽  
Immunosorbent Assay ◽  
Signal Amplification ◽  
Specific Antigen ◽  
Enzyme Linked Immunosorbent Assay ◽  
Core Shell ◽  
Elisa System ◽  
System P ◽  
Amplification Strategy

A colorimetric/fluorescence/photoacoustic triple read-out detection of prostate specific antigen (PSA) was developed by using a silica coated Au@Ag core–shell nanorod (denoted Au@Ag@SiO2) based enzyme-linked immunosorbent assay (ELISA) system.

An Fe3O4/PEDOT:PSS nanocomposite as an advanced electroconductive material for the biosensing of the prostate-specific antigen in unprocessed human plasma samples

2019 ◽  
Vol 11 (44) ◽  
pp. 5661-5672 ◽  
Author(s):  
Mina Shaban ◽  
Mohammad Hasanzadeh ◽  
Elham Solhi
Keyword(s):  
Human Plasma ◽  
Prostate Specific Antigen ◽  
Signal Amplification ◽  
Specific Antigen ◽  
Plasma Samples ◽  
Real Samples ◽  
Human Plasma Samples ◽  
Sandwich Type ◽  
Amplification Strategy

A novel sandwich-type biosensor based on a signal amplification strategy of various nanocomposites was developed to monitor the prostate-specific antigen (PSA) in real samples.

Initial Study of Thin-Film Derived Gold Nanoparticles (Au NPs) Surface Plasmon Resonance (SPR) Based Prostate-Specific Antigen (PSA) Detection

2020 ◽  
Vol 18 (11) ◽  
pp. 781-784
Author(s):  
M. Dhanunjaya ◽  
T. Sonklin ◽  
Pimchanok Leuasoongnoen ◽  
Sanong Suksaweang ◽  
Pattanaphong Janphuang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Surface Plasmon Resonance ◽  
Prostate Specific Antigen ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Specific Antigen ◽  
Initial Study ◽  
Peak Position ◽  
Localized Surface Plasmon ◽  
Au Nps

The gold nanoparticles (Au NPs) localized surface plasmon resonance (LSPR) based detection of prostate-specific antigen (PSA) biomarker was carried out in this work. Au NPs on Si and quartz substrates were synthesized by DC magnetron sputtering method followed by conventional annealing protocol. The functionalization of antibody and PSA with Au NPs was evaluated using a simple drop-cost method. The SPR peak intensity was found to be proportional to the PSA concentration. The redshift in SPR peak position might be owing to the change in refractive index around the Au NPs with the conjugation of antibody and further additional binding of specific PSA at different concentrations.

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