Fabrication of an efficient ZIF-8 alginate composite hydrogel material and its application for enhanced copper (II) adsorption from aqueous solutions

2021 ◽  
Author(s):  
Xiao Zhang ◽  
Zhiyue Li ◽  
Taoyi Zhang ◽  
Jing Chen ◽  
Wenxi Ji ◽  
...  

A novel zeolitic imidazolate framework-8 (ZIF-8) alginate composite hydrogel material (PVA/SA@ZIF-8) is alginate composite bead which was fabricated by grafting ZIF-8 on the surface of the sodium alginate hydrogel beads...

RSC Advances ◽  
2019 ◽  
Vol 9 (48) ◽  
pp. 27961-27972
Author(s):  
Dan Zheng ◽  
Bo Bai ◽  
Xiaohui Xu ◽  
Yunhua He ◽  
Shan Li ◽  
...  

Composite hydrogel beads prepared by sodium alginate with hydrophilicity and detonation nanodiamond with photothermal conversion property exhibited apparent water release behavior under illumination.


2021 ◽  
Vol 8 ◽  
Author(s):  
Bin Zhao ◽  
Jingya He ◽  
Feng Wang ◽  
Ruxiao Xing ◽  
Bin Sun ◽  
...  

Oxygen is essential for cell survival and tissue regeneration. Scaffolds releasing oxygen have been hypothesized as an ideal strategy for bone repair. However, excessive oxygen supply will disturb the redox balance, lead to oxidative stress, and affect bone regeneration. In this study, we synthesized a hydrogel from sodium alginate and loaded it calcium peroxide nanoparticles as an oxygen generating material and vitamin C as a pH regulator and antioxidant. The composite hydrogel, with a pH value close to physiological humoral fluid, could release oxygen to alleviate hypoxia in the bone defect and reduce the side effects of excessive hydrogen peroxide. In in vitro experiments, the composite hydrogel promoted the osteogenic differentiation and ALP and mineralization ability of rat bone marrow mesenchymal stem cells in a hypoxic environment (2% O2). In animal experiments, the composite hydrogel was applied in rat skull defect models. It promoted the healing of bone defects. These results suggest that sodium alginate hydrogel releasing oxygen and vitamin C is suitable for cell survival and tissue regeneration in a hypoxic environment and has good application prospects in bone defect repair.


Author(s):  
Siti Sabrina Mohd Sukri ◽  
Mimi Sakinah A.M

Enzymes serving as biocatalysts and play an important roles in many industrial field. However, the limitation of enzyme usage due to its high cost and unstable conditions of soluble enzyme to harsh conditions lead to findings an alternative to enhance the enzyme efficiency by immobilisation (insoluble enzyme). The present work reported a combination of immobilisation technique of xylanase by entrapment and covalent binding on alginate hydrogel beads. Xylanase enzyme was effectively immobilised within the support matrix, alginate hydrogel beads by entrapment and covalent binding on the surface of beads using glutaraldehyde as a cross-linked agent. The effects of support matrix comprised of sodium alginate concentration (% w/v) and calcium chloride, CaCl2 (M) were studied in order to obtain a better immobilisation yield. The suitable concentration of sodium alginate and CaCl2 to ensure a robust and stable hydrogel beads with higher immobilisation yield were formed as a support matrix for xylanase immobilisation. The analysis of xylanase activity was determined using dinitrosalicyclic (DNS) acid reagent method. Maximal enzyme immobilisation yield (>80 %) was achieved at 3.0 % w/v of sodium alginate concentration and 0.3 M of CaCl2. The study shows the support matrix of hydrogel beads gave a significant impact towards the immobilisation yield of xylanase.


Cellulose ◽  
2013 ◽  
Vol 20 (3) ◽  
pp. 1261-1273 ◽  
Author(s):  
Bala Yerri Swamy ◽  
Jeong Hyun Chang ◽  
Heejoon Ahn ◽  
Won-Ki Lee ◽  
Ildoo Chung

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