Visible light-promoted aerobic oxidative cleavage and cyclization of olefins to access 3-hydroxy-isoindolinones

2021 ◽  
Author(s):  
Tao Ma ◽  
Jiawei Hua ◽  
Mixue Bian ◽  
Hong Qin ◽  
Xinxin Lin ◽  
...  
Keyword(s):  
Visible Light ◽  
Molecular Oxygen ◽  
Environmentally Friendly ◽  
Oxidative Cleavage ◽  
Synthetic Approach ◽  
Iron Disulfide ◽  
Oxygen Oxidation

An environmentally friendly synthetic approach is described from 2-vinylbenzamide to 3-hydroxy-isoindolinones through visible light-promoted transformations via iron/disulfide catalysis and molecular oxygen oxidation.

Visible Light-Induced Synthetic Approach for Selenylative Spirocyclization of N -Aryl Alkynamides with Molecular Oxygen as Oxidant

2018 ◽  
Vol 360 (6) ◽  
pp. 1099-1103 ◽  
Author(s):  
Harekrishna Sahoo ◽  
Anup Mandal ◽  
Suman Dana ◽  
Mahiuddin Baidya
Keyword(s):  
Visible Light ◽  
Molecular Oxygen ◽  
Synthetic Approach

Optical Properties of Photodynamic Therapy Drugs in Different Environments: The Paradigmatic Case of Temoporfin

2020 ◽  
Author(s):  
busenur Aslanoglu ◽  
Ilya Yakavets ◽  
Vladimir Zorin ◽  
Henri-Pierre Lassalle ◽  
Francesca Ingrosso ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Optical Properties ◽  
Photodynamic Therapy ◽  
Minimally Invasive ◽  
Visible Light ◽  
Cancer Treatment ◽  
Singlet Oxygen ◽  
Tumor Cells ◽  
Molecular Oxygen ◽  
Computational Tools

Computational tools have been used to study the photophysical and photochemical features of photosensitizers in photodynamic therapy (PDT) –a minimally invasive, less aggressive alternative for cancer treatment. PDT is mainly based by the activation of molecular oxygen through the action of a photoexcited sensitizer (photosensitizer). Temoporfin, widely known as mTHPC, is a second-generation photosensitizer, which produces the cytotoxic singlet oxygen when irradiated with visible light and hence destroys tumor cells. However, the bioavailability of the mostly hydrophobic photosensitizer, and hence its incorporation into the cells, is fundamental to achieve the desired effect on malignant tissues by PDT. In this study, we focus on the optical properties of the temoporfin chromophore in different environments –in <i>vacuo</i>, in solution, encapsulated in drug delivery agents, namely cyclodextrin, and interacting with a lipid bilayer.

Visible-light-initiated Catalyst-free Oxidative Cleavage of Triaryl-Substituted Alkenes C=C Bonds under Ambient Conditions

2021 ◽  
Author(s):  
Wenjing Li ◽  
Shun Li ◽  
Lihua Luo ◽  
Yichen Ge ◽  
Jiaqi Xu ◽  
...  
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Ambient Air ◽  
Oxidative Cleavage ◽  
Ambient Conditions ◽  
Blue Led ◽  
Catalyst Free

The catalyst-free oxidative cleavage of (Z)-triaryl-substituted alkenes bearing pyridyl motif with ambient air under irradiation of blue LED at room temperature has been developed. The reaction was facile and scalable,...

Visible-light-induced oxidative coupling of vinylarenes with diselenides leading to α-aryl and α-alkyl selenomethyl ketones

2021 ◽  
Author(s):  
Gong-Qing Liu ◽  
Wei Yi ◽  
Peng-Fei Wang ◽  
Ji Liu ◽  
Meng Ma ◽  
...  
Keyword(s):  
Visible Light ◽  
Oxidative Coupling ◽  
Environmentally Friendly

An environmentally friendly protocol for the synthesis of α-aryl and α-alkyl selenomethyl ketones is reported herein.

Visible-Light-Mediated Organoboron-Catalysed Metal-Free Dehydrogenation of N-Heterocycles Using Molecular Oxygen

2021 ◽  
Author(s):  
Lanfeng Wei ◽  
Yu Wei ◽  
Jinli Zhang ◽  
Liang Xu
Keyword(s):  
Visible Light ◽  
Molecular Oxygen ◽  
The Other ◽  
Metal Free ◽  
Other Hand

The surge of photocatalytic transformation not only provides unprecedented synthetical methods, but also triggers the enthusiasm for more sustainable photocatalysts. On the other hand, oxygen is an ideal oxidant in...

Visible-light-responsive lanthanide coordination polymers for highly efficient photocatalytic aerobic oxidation of amines and thiols

2021 ◽  
Author(s):  
Zhifen Guo ◽  
Xin Liu ◽  
Yan Che ◽  
Hongzhu Xing ◽  
Peng Chen
Keyword(s):  
Visible Light ◽  
Molecular Oxygen ◽  
Coordination Polymers ◽  
Aerobic Oxidation ◽  
Synthesis And Characterization ◽  
Lanthanide Coordination Polymers ◽  
Highly Efficient ◽  
Photocatalytic Reactions ◽  
Energy Issues

Development of visible-light-induced photocatalytic reactions using molecular oxygen as terminal oxidant is intriguing in view of the current environmental and energy issues. We report herein the synthesis and characterization of...

Oxidative cleavage of CC bond of 2-phenylpropionaldehyde using molecular oxygen

2006 ◽  
Vol 117 (1-3) ◽  
pp. 138-140 ◽  
Author(s):  
M TOKUNAGA ◽  
H AOYAMA ◽  
Y SHIROGANE ◽  
Y OBORA ◽  
Y TSUJI
Keyword(s):  
Molecular Oxygen ◽  
Oxidative Cleavage

scholarly journals Visible light mediated aerobic oxidative hydroxylation of 2-oxindole-3-carboxylate esters: an alternative approach to 3-hydroxy-2-oxindoles

2020 ◽  
Vol 26 (1) ◽  
pp. 168-175
Author(s):  
Jinge Wang ◽  
Siyitemer Osman ◽  
Xinjiang Lu ◽  
Junyi Chen ◽  
Xu-Dong Xia
Keyword(s):  
Visible Light ◽  
Molecular Oxygen ◽  
Reaction Conditions ◽  
Alternative Approach

AbstractA convenient aerobic oxidative hydroxylation of 3-substituted oxindoles under mild reaction conditions is described herein. This process was accomplished by the activation of molecular oxygen in the air in the presence of a photocatalyst under the irradiation of visible light. The desired product was delivered in up to 89% yield without the addition of base or stoichiometric oxidant.

Acetylation of Alcohols and Amines under Visible Light Irradiation: Diacetyl as an Acylation Reagent and Photosensitizer

2021 ◽  
Author(s):  
Pengcheng Lian ◽  
Ruyi Li ◽  
Xiao Wan ◽  
Zixin Xiang ◽  
Hang Liu ◽  
...  
Keyword(s):  
Visible Light ◽  
Visible Light Irradiation ◽  
Functional Group ◽  
Environmentally Friendly ◽  
Light Irradiation ◽  
Environmentally Friendly Process

This work developed an unprecedented strategy for the acetylation of alcohols and amines using diacetyl as both an acylation reagent and photosensitizer. This environmentally friendly process exhibits excellent functional group...

Sign in / Sign up

Export Citation Format

Share Document