scholarly journals Regulatory and microbiological safety issues surrounding cell and tissue-engineering products

2004 ◽  
Vol 40 (1) ◽  
pp. 35 ◽  
Author(s):  
Daniel N. Galbraith
Keyword(s):  
Tissue Engineering ◽  
Safety Issues ◽  
Microbiological Safety ◽  
Surrounding Cell

Microbiological Safety Issues of Fresh Melons

2005 ◽  
pp. 231-251 ◽  
Author(s):  
Dike Ukuku ◽  
Gerald Sapers
Keyword(s):  
Safety Issues ◽  
Microbiological Safety

Pinocytotic-Like Forms of Mitochondria From Rat Anterior Pituitary

1968 ◽  
Vol 26 ◽  
pp. 146-147
Author(s):  
Burton B. Silver
Keyword(s):  
Electron Micrographs ◽  
Conformational Changes ◽  
Anterior Pituitary ◽  
Dynamic State ◽  
Surrounding Cell ◽  
The Matrix ◽  
The Moment ◽  
Cell Medium ◽  
Sectioned Tissue ◽  
State Of Activity

Sectioned tissue rarely indicates evidence of what is probably a highly dynamic state of activity in mitochondria which have been reported to undergo a variety of movements such as streaming, divisions and coalescence. Recently, mitochondria from the rat anterior pituitary have been fixed in a variety of configurations which suggest that conformational changes were occurring at the moment of fixation. Pinocytotic-like vacuoles which may be taking in or expelling materials from the surrounding cell medium, appear to be forming in some of the mitochondria. In some cases, pores extend into the matrix of the mitochondria. In other forms, the remains of what seems to be pinched off vacuoles are evident in the mitochondrial interior. Dense materials, resembling secretory droplets, appear at the junction of the pores and the cytoplasm. The droplets are similar to the secretory materials commonly identified in electron micrographs of the anterior pituitary.

Controlling the in vitro differentiation of embryonic stem cells for myocardial tissue engineering applications

2009 ◽  
Author(s):  
Dong-Bo Ou ◽  
Rui Chen ◽  
Xiong-Tao Liu ◽  
Jing-Jing Guo ◽  
Hong-Tao Wang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Myocardial Tissue ◽  
In Vitro Differentiation ◽  
Engineering Applications ◽  
Myocardial Tissue Engineering

Decellularized bone extracellular matrix in skeletal tissue engineering

2020 ◽  
Vol 48 (3) ◽  
pp. 755-764
Author(s):  
Benjamin B. Rothrauff ◽  
Rocky S. Tuan
Keyword(s):  
Tissue Engineering ◽  
Bone Regeneration ◽  
Tissue Regeneration ◽  
Animal Studies ◽  
Tumor Resection ◽  
Regenerative Capacity ◽  
Skeletal Tissue ◽  
Large Bone

Bone possesses an intrinsic regenerative capacity, which can be compromised by aging, disease, trauma, and iatrogenesis (e.g. tumor resection, pharmacological). At present, autografts and allografts are the principal biological treatments available to replace large bone segments, but both entail several limitations that reduce wider use and consistent success. The use of decellularized extracellular matrices (ECM), often derived from xenogeneic sources, has been shown to favorably influence the immune response to injury and promote site-appropriate tissue regeneration. Decellularized bone ECM (dbECM), utilized in several forms — whole organ, particles, hydrogels — has shown promise in both in vitro and in vivo animal studies to promote osteogenic differentiation of stem/progenitor cells and enhance bone regeneration. However, dbECM has yet to be investigated in clinical studies, which are needed to determine the relative efficacy of this emerging biomaterial as compared with established treatments. This mini-review highlights the recent exploration of dbECM as a biomaterial for skeletal tissue engineering and considers modifications on its future use to more consistently promote bone regeneration.

NSAIDs' Safety Issues May Spur Clinical Change

2005 ◽  
Vol 36 (9) ◽  
pp. 50-51
Author(s):  
BRUCE JANCIN
Keyword(s):  
Clinical Change ◽  
Safety Issues

Classification of Health/Safety Issues/Concerns and Solutions Identified by Participatory Design Teams

2012 ◽  
Author(s):  
Scott Ryan ◽  
◽  
Megan Dove-Steinkamp ◽  
Suzanne Nobrega ◽  
Lize Tibirica ◽  
...  
Keyword(s):  
Participatory Design ◽  
Design Teams ◽  
Health Safety ◽  
Safety Issues

Tissue engineering: Tough networks

2009 ◽  
Vol 1 (1) ◽  
pp. 9-9
Keyword(s):  
Tissue Engineering
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