Deoxyribonucleic acid-dependent ribonucleic acid polymerase activity in rat liver after protein restriction

1975 ◽  
Vol 148 (3) ◽  
pp. 353.b1-353.b1
Keyword(s):  
Rat Liver ◽  
Ribonucleic Acid ◽  
Deoxyribonucleic Acid ◽  
Polymerase Activity ◽  
Protein Restriction

THE INFLUENCE OF GROWTH HORMONE ON THE NUCLEIC ACID CONTENT OF RAT LIVER AND MUSCLE

1956 ◽  
Vol 13 (4) ◽  
pp. 429-432 ◽  
Author(s):  
BARBARA J. GRAY
Keyword(s):  
Skeletal Muscle ◽  
Growth Hormone ◽  
Nucleic Acid ◽  
Rat Liver ◽  
Ribonucleic Acid ◽  
Acid Content ◽  
Deoxyribonucleic Acid ◽  
Female Rats ◽  
Nucleic Acid Content ◽  
Pituitary Growth Hormone

SUMMARY Adult female rats were treated with purified pituitary growth hormone for 9 days, and the nucleic acid content of the liver and skeletal muscle determined. An increase was observed in the concentration of muscle ribonucleic acid, expressed per gram of nitrogen, as a result of the treatment. There were no changes in the ribonucleic acid concentration of liver. No changes were observed in the concentration of deoxyribonucleic acid in muscle or liver.

scholarly journals The effects of copper and other ions on the ribonucleic acid polymerase activity of isolated rat liver nuclei

1969 ◽  
Vol 111 (1) ◽  
pp. 115-119 ◽  
Author(s):  
F. Novello ◽  
F. Stirpe
Keyword(s):  
Rna Polymerase ◽  
Ammonium Sulphate ◽  
Rat Liver ◽  
Ribonucleic Acid ◽  
Polymerase Activity ◽  
Isolated Rat Liver ◽  
Rat Liver Nuclei ◽  
Liver Nuclei ◽  
Isolated Liver ◽  
Isolated Rat

1. The effects of various ions on the Mg2+- and Mn2+/ammonium sulphate-activated RNA polymerase activities of isolated liver nuclei were studied. 2. The Mg2+-activated RNA polymerase reaction was inhibited by more than 60% by Cd2+, SeO32−, Be2+, Cu2+, Co2+, Ca2+ and La3+, all at 1mm concentrations. 3. The Mn2+/ammonium sulphate-activated RNA polymerase reaction was strongly inhibited by Hg2+, Cd2+, Cu2+ and Ag+. The effect of Hg2+, Cd2+ and Ag+ was relieved by cysteine or mercaptoethanol. 4. Inhibition by Cu2+ was not affected by addition of DNA, and was relieved only partially by EDTA or histidine. 5. No changes of RNA polymerase activities were observed in nuclei isolated from the liver of rats treated with copper albuminate.

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