Brain nitric oxide synthase is a haemoprotein
Keyword(s):
Brain nitric oxide (NO) synthase showed pyridine haemochrome spectra typical of ferroprotoporphyrin IX-containing enzymes. The haem content of purified NO synthase was in the range 0.7-0.9 mol/mol of 160 kDa subunit. In the presence of CO, NO, KCN and miconazole, the L-citrulline-forming activity of NO synthase was markedly diminished, demonstrating that enzyme-bound haem is involved in enzymic NO synthesis.
1994 ◽
Vol 269
(19)
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pp. 13861-13866
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Keyword(s):
2002 ◽
Vol 102
(1-2)
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pp. 1-7
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1995 ◽
Vol 14
(15)
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pp. 3687-3695
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Keyword(s):
2019 ◽
Vol 36
(3)
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pp. 523-539
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Keyword(s):
1994 ◽
Vol 81
(SUPPLEMENT)
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pp. A807
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Keyword(s):
Keyword(s):
1993 ◽
Vol 265
(5)
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pp. C1379-C1387
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