Reversed Diurnal Blood Pressure Rhythm in Hypertensive Pregnancies

1976 ◽  
Vol 51 (s3) ◽  
pp. 687s-689s ◽  
Author(s):  
C. W. G. Redman ◽  
L. J. Beilin ◽  
J. Bonnar
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Severe Hypertension ◽  
Practical Importance ◽  
Theoretical Interest ◽  
Hypotensive Drug ◽  
Pressure Pattern ◽  
Nocturnal Hypertension ◽  
Hypertension In Pregnancy ◽  
In Pregnancy

1. Reversal of the normal diurnal blood pressure pattern has been demonstrated in women with severe hypertension and renal impairment in pregnancy (pre-eclampsia). 2. Maximum arterial pressure occurred at night in these women. The phenomenon was not due to hypotensive drug therapy or posture. Patients with uncomplicated essential hypertension in pregnancy retained a normal diurnal blood pressure pattern. 3. Nocturnal hypertension in pre-eclampsia is of theoretical interest and practical importance.

Management of hypertension in pregnancy

1967 ◽  
Vol 5 (13) ◽  
pp. 49-51
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Renal Biopsy ◽  
Lower Threshold ◽  
General Physician ◽  
Maternal Deaths ◽  
Hypertension In Pregnancy ◽  
Hypotensive Drugs ◽  
Treatment Of Hypertension ◽  
In Pregnancy

Perinatal and maternal deaths are increased by hypertension in pregnancy.1 2 This comprises (1) essential hypertension, (2) other varieties of hypertension, (3) pre-eclamptic toxaemia of pregnancy, and (4) toxaemia complicating (1) and (2). The treatment of hypertension in pregnancy varies considerably, particularly in the use of hypotensive drugs. This variation arises partly because the obstetrician has a lower threshold for what constitutes ‘hypertension’ in his patients than has the general physician, partly because pre-eclamptic toxaemia is difficult to distinguish from essential and other hypertension in pregnancy and partly from our ignorance of the aetiology and fundamental lesion in the former. Specific microscopic changes have been found on renal biopsy,3 but these lesions may be present in only a minority of those diagnosed clinically as toxaemia.4 At present therefore treatment can only be directed at lowering the blood pressure.

scholarly journals A STUDY ON IV LABETALOL VERSUS ORAL NIFEDIPINE IN ACUTE CONTROL OF SEVERE HYPERTENSION IN PREGNANCY

2020 ◽  
pp. 1-4
Author(s):  
G. Kesava Chand ◽  
Sireesha Ratal
Keyword(s):  
Blood Pressure ◽  
Severe Hypertension ◽  
Tertiary Hospital ◽  
Target Blood Pressure ◽  
10Mg Tablet ◽  
Hypertension In Pregnancy ◽  
Group 5 ◽  
Double Blinded ◽  
To Receive ◽  
In Pregnancy

Objective: To compare the efficacy of IV Labetalol with oral Nifedipine in the treatment of severe hypertension in pregnancy with blood pressure >160/110mm Hg. Methods:A parallel double blinded randomized control trial between Jan 2019 and May 2019 in 100 antenatal women of gestational age>28 weeks, admitted with blood pressure >160/110 mm Hg conducted in labour ward tertiary hospital. Antenatal women were randomized to receive oral Nifedipine 10mg tablet orally up to 5 doses and IV Labetalol was initiated at 20mg and in escalating doses of 20mg, 40mg.80mg, and 80mg up to 220mg. The number of doses and meantime taken to achieve target blood pressure <140/90 mm Hg was noted. Results:hundred antenatal women were randomized to 50 in each group.In the Labetalol group 5 patients required oral Nifedipine to achieve target blood pressure but none in the Nifedipine group. The numbers of doses required and meantime taken to achieve target bloodpressure in nefidipine group were less compared to that of Labetalol group. Conclusion: IV Labetalol and oral Nifedipine were equally effectively to achieve target blood pressure.Incomparsion, oral Nifedipine achieved target blood pressure more quickly than Labetalo

DAILY BLOOD PRESSURE PATTERN DISORDERS IN PATIENTS WITH STAGE II ESSENTIAL HYPERTENSION AND FREQUENT PREMATURE BEATS

2020 ◽  
Vol 16 (71) ◽  
pp. 072
Author(s):  
N. V. Kuzminova ◽  
A. V. Ivankova ◽  
V. P. Ivanov ◽  
S. E. Lozinsky ◽  
I. I. Knyazkova ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Stage Ii ◽  
Pressure Pattern ◽  
Premature Beats

Essential Hypertension in Pregnancy

BMJ ◽  
1949 ◽  
Vol 2 (4630) ◽  
pp. 758-758
Author(s):  
R. H. Paramore
Keyword(s):  
Essential Hypertension ◽  
Hypertension In Pregnancy ◽  
In Pregnancy

Hypertensive Disorders in Pregnancy

2017 ◽  
Author(s):  
Kavitha Vellanki ◽  
Susan Hou
Keyword(s):  
Blood Pressure ◽  
Organ Damage ◽  
The United States ◽  
Blood Pressure Target ◽  
Maternal Complications ◽  
Hypertension In Pregnancy ◽  
Hypertensive Disorders ◽  
Few Data ◽  
In Pregnancy ◽  
New Onset

Hypertensive disorders are the second leading cause of maternal mortality in the United States. Hypertension in pregnancy is defined as blood pressure greater than or equal to 140 mm Hg systolic or greater than or equal to 90 mm Hg diastolic, measured on at least two separate occasions. Preeclampsia, as per the new guidelines, is characterized by the new onset of hypertension and either proteinuria or other end-organ dysfunction, more often after 20 weeks of gestation in a previously normotensive pregnant woman. New-onset proteinuria is not required for diagnosis of preeclampsia if there is evidence of other end-organ damage—a change from previous classifications. Although no screening test has yet proven accurate enough to predict preeclampsia, the use of a combination of the serologic factors seems promising. There are few data to support any specific blood pressure target in pregnancy. Although there is a general consensus on treating severe hypertension in pregnancy, there is a difference of opinion on treating mild to moderate hypertension in pregnancy. Avoiding uteroplacental ischemia and minimizing fetal exposure to adverse effects of medications are as important as avoiding maternal complications from high blood pressure during pregnancy. This review contains 2 figures, 4 tables, and 73 references.

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