Role of Plasma Vasopressin in the Development of Polyuria in Uncontrolled Diabetes Mellitus

1980 ◽  
Vol 58 (2) ◽  
pp. 27P-27P
Author(s):  
J. J. Milles ◽  
P. H. Baylis ◽  
A. D. Wright
Diabetes ◽  
1979 ◽  
Vol 28 (5) ◽  
pp. 503-508 ◽  
Author(s):  
R. L. Zerbe ◽  
F. Vinicor ◽  
G. L. Robertson

1994 ◽  
Vol 5 (5) ◽  
pp. S29
Author(s):  
J H Dominguez ◽  
B Song ◽  
L Maianu ◽  
W T Garvey ◽  
M Qulali

The functions of absorption of dietary glucose by the small intestine and reabsorption of filtered glucose by the renal proximal tubule are strikingly similar in their organization and in the way they adapt to uncontrolled diabetes mellitus. In both cases, transepithelial glucose and Na+ fluxes are augmented. The epithelial adaptations to hyperglycemia of uncontrolled diabetes are accomplished by increasing the glucose transport surface area and the number of the efflux glucose transporter GLUT2 located in the basolateral membrane. The signals that modify the size of the epithelium and the overexpression of basolateral GLUT2 are not known. It was speculated that high glucose levels and enhanced Na+ flux may be important factors in the signaling event that culminates in a renal and intestinal epithelium that is modified to transport higher rates of glucose against a higher extracellular level of glucose.


Diabetes ◽  
1979 ◽  
Vol 28 (5) ◽  
pp. 503-508 ◽  
Author(s):  
R. L. Zerbe ◽  
F. Vinicor ◽  
G. L. Robertson

2016 ◽  
Vol 10 (4) ◽  
Author(s):  
Shumaila Seemi Malik ◽  
Naeem Ahmad Khan ◽  
Safdar Ali Malik

The study was carried out on eight patients with clinical presentation of non-traumatic painful swelling of lower limbs & were examined with high resolution Ultrasound probe of 12 MHz on Logic 700 expert series, with average patients age of about 37 years with H/O of uncontrolled diabetes Mellitus, showed discrepancy of circumference / thickness of Calf muscles compared to the opposite normal lower limb with areas of low echogenicity & one patient showed areas of necrosis / abscesses in muscle planes. All were diagnosed & latter confirmed on biopsy as Diabetic muscle infarctions with superadded inflammation.


2012 ◽  
Vol 3 (1) ◽  
pp. 315-316
Author(s):  
Dr. Sanay Prajapati ◽  
◽  
Dr. Divyesh Patel ◽  
Dr. Jay Panchal ◽  
Dr. Viplav Gndhi ◽  
...  

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