Could the A2A11 Human Leucocyte Antigen Locus Correlate with Maximal Aerobic Power?

1997 ◽  
Vol 92 (4) ◽  
pp. 331-333 ◽  
Author(s):  
GIL Rodas ◽  
Guadalupe Ercilla ◽  
Casimiro Javierre ◽  
Eduardo Garrido ◽  
MAR Calvo ◽  
...  
Keyword(s):  
Human Leucocyte Antigen ◽  
Aerobic Power ◽  
Maximal Aerobic Power ◽  
Hla System ◽  
Sports Events ◽  
Progressive Exercise ◽  
Genetic Endowment ◽  
Sporting Activities ◽  
The Relationship ◽  
Male Twin

1. The power of the aerobic metabolic pathway correlates well with successful physical performance in endurance sports events. The ability to alter the pathway through training presents well-known limitations, and consequently a good genetic endowment is essential to participate in elite sporting activities. 2. In 32 subjects (16 healthy pairs of male twin sportsmen, 8 monozygotic and 8 dizygotic) zygosity was determined by means of the genetic analysis of human leucocyte antigen (HLA) system specificities at class I and II loci and other genetic variants. The subjects performed a progressive exercise test on a treadmill to ascertain the maximal oxygen uptake (V̇O2max), measured by an automatic breath-by-breath analyser. We have considered the relationship between the A, B and C loci of the HLA system and V̇O2max. 3. We found a high correlation between the presence of both HLA A2 and All and V̇O2max. In the A2A11 group (n = 6) we found a V̇O2max (mean ± SD) equal to 71 ± 4 ml min−1 kg−1. The group without this pair of alleles (n = 26) showed a much lower aerobic power (58 ±5 ml min−1 kg−1). Differences between the two groups were found to be largely significant (P < 0.001). It is noteworthy that in two pairs of dizygotic twins, the higher V̇O2max value corresponded to the twin with the A2A11 allele. 4. The very marked concordance between the presence of the A2A11 locus of the HLA system and the V̇O2max could be of great interest for the identification of outstanding performers.

Maximal Aerobic Power in Aging Men: Insights From a Record of 1-Hour Unaccompanied Cycling

2018 ◽  
Vol 13 (1) ◽  
pp. 112-114 ◽  
Author(s):  
Carlo Capelli
Keyword(s):  
Aerobic Power ◽  
Average Rate ◽  
Human Locomotion ◽  
Maximal Aerobic Power ◽  
Metabolic Power ◽  
Master Athletes ◽  
Active Lifestyle ◽  
Average Percentage ◽  
Aging Men ◽  
The Relationship

Purpose: To analyze best 1-h unaccompanied performances of master athletes in ages ranging from 35 to 105 y to estimate the decay of maximal aerobic power (MAP) across the spectrum of age. Methods: MAP at the various ages was estimated by computing the metabolic power () maintained to cover the distances during best 1-h unaccompanied performances established by master athletes of different classes of age and by assuming that they were able to maintain an equal to 88% of their MAP during 1 h of exhaustive exercise. Results: MAP started monotonically decreasing at 47 y of age. Thereafter, it showed an average rate of decrease of ∼14% for the decades up to 105 y of age, similar to other classes of master athletes. Conclusions: The results confirm, by extending the analysis to centennial subjects, that MAP seems to start declining from the middle of the 5th decade of age, with an average percentage decay that is faster than that traditionally reported, even when one maintains a very active lifestyle. The proposed approach may be applied to other types of human locomotion for which the relationship between speed and is known.

The relationship between changing body height and growth related changes in maximal aerobic power

1990 ◽  
Vol 60 (4) ◽  
pp. 282-287 ◽  
Author(s):  
J. Rutenfranz ◽  
M. Máček ◽  
K. Lange Andersen ◽  
R. D. Bell ◽  
J. Vávra ◽  
...  
Keyword(s):  
Aerobic Power ◽  
Body Height ◽  
Maximal Aerobic Power ◽  
The Relationship

Maximal aerobic exercise in pregnant women: heart rate, O2 consumption, CO2 production, and ventilation

1991 ◽  
Vol 70 (3) ◽  
pp. 1016-1023 ◽  
Author(s):  
F. K. Lotgering ◽  
M. B. van Doorn ◽  
P. C. Struijk ◽  
J. Pool ◽  
H. C. Wallenburg
Keyword(s):  
Heart Rate ◽  
Aerobic Power ◽  
Treadmill Exercise ◽  
Statistical Significance ◽  
Maximal Aerobic Power ◽  
Co2 Production ◽  
Maximal Heart Rate ◽  
O2 Uptake ◽  
Positive Linear Correlation ◽  
The Relationship

This study was to determine whether pregnancy affects maximal aerobic power. We measured heart rate, O2 uptake (VO2), CO2 production (VCO2), and ventilation at rest and during bicycle (BE) and treadmill exercise (TE) tests with rapidly increasing exercise intensities at 16, 25, and 35 wk gestation and 7 wk after delivery. Maximal heart rate was slightly lower throughout pregnancy compared with the nonpregnant state during both BE [174 +/- 2 vs. 178 +/- 2 (SE) beats/min] and TE (178 +/- 2 vs. 183 +/- 2 beats/min). Maximal VO2 was unaffected by pregnancy during BE and TE (2.20 +/- 0.08, 2.16 +/- 0.08, 2.15 +/- 0.08, and 2.19 +/- 0.08 l/min for BE and 2.45 +/- 0.08, 2.38 +/- 0.09, 2.33 +/- 0.09, and 2.39 +/- 0.08 l/min for TE at 16, 25, and 35 wk gestation and 7 wk postpartum, respectively). As a result of increased VO2 at rest, the amount of O2 available for exercise (exercise minus rest) tended to decrease with advancing gestation, reaching statistical significance only during TE at 35 wk gestation (1.99 +/- 0.08 l/min vs. 2.10 +/- 0.08 l/min postpartum). Power showed a positive linear correlation with O2 availability during BE as well as TE, and the relationship was unaffected by pregnancy.(ABSTRACT TRUNCATED AT 250 WORDS)

Maximal aerobic power in essential hypertension

1988 ◽  
Vol 6 (11) ◽  
pp. 859-865 ◽  
Author(s):  
Robert Fagard ◽  
Jan Staessen ◽  
Antoon Amery
Keyword(s):  
Essential Hypertension ◽  
Aerobic Power ◽  
Maximal Aerobic Power

Prediction of maximal aerobic power in man

1977 ◽  
Vol 36 (3) ◽  
pp. 215-222 ◽  
Author(s):  
S. S. Verma ◽  
J. Sen Gupta ◽  
M. S. Malhotra
Keyword(s):  
Aerobic Power ◽  
Maximal Aerobic Power

Criminal Liability of Athletes for Damage Caused as a Result of Violation of the Rules of Sports Events

2020 ◽  
Vol 12 ◽  
pp. 100-105
Author(s):  
D. A. Bezborodov ◽  
◽  
R. M. Kravchenko ◽  
Keyword(s):  
Law Enforcement ◽  
Sports Injuries ◽  
Criminal Liability ◽  
Sporting Events ◽  
Sports Training ◽  
Training Process ◽  
Sports Organizations ◽  
Sports Events ◽  
Special Rules ◽  
The Relationship

The article deals with issues related to the characteristics of the qualification of causing injury or death to an athlete during sports events. The article analyzes the possibility of applying the provisions of certain circumstances that exclude the criminality of the act. Take into account that the relationship between the participants of sports competitions and sports training, while relationships at the same time are not regulated by the law and sports regulations sports, and the internal rules of sports organizations, defining the organization of the training process. Therefore, the issues related to the influence of special rules regulating the procedure for conducting sports competitions and other sporting events on the features of criminal liability (in particular, guilt), both athletes and other persons who ensure the conduct of sports events, are studied specifically. It is taken into account that modern legislation and law enforcement often ignores this requirement, which, in particular, is expressed in the failure to include the facts of sports injuries in the list of crimes in the field of sports. First of all, the article analyzes the issues of criminal-legal assessment of an athlete's act in the event of injury to health or death to another athlete, given that in sports, harm is usually caused unintentionally, by negligence. Therefore, the work analyzes the risks, harm to health, as well as measures that should have been taken by the organizers of the competition to avoid causing harm, taking into account that all these issues are evaluative. The characteristic of harming an athlete while observing the rules of events by his opponent is given. The question of how the rules relating to a particular sport can exempt a person from liability for causing harm is being investigated.

Threshold for muscle lactate accumulation during progressive exercise

1989 ◽  
Vol 66 (6) ◽  
pp. 2710-2716 ◽  
Author(s):  
J. Chwalbinska-Moneta ◽  
R. A. Robergs ◽  
D. L. Costill ◽  
W. J. Fink
Keyword(s):  
Blood Lactate ◽  
Bicycle Ergometer ◽  
Exercise Tests ◽  
Muscle Lactate ◽  
Lactate Accumulation ◽  
Ergometer Exercise ◽  
Progressive Exercise ◽  
Blood Lactate Accumulation ◽  
Highly Correlated ◽  
The Relationship

The purpose of this study was to investigate the relationship between muscle and blood lactate concentrations during progressive exercise. Seven endurance-trained male college students performed three incremental bicycle ergometer exercise tests. The first two tests (tests I and II) were identical and consisted of 3-min stage durations with 2-min rest intervals and increased by 50-W increments until exhaustion. During these tests, blood was sampled from a hyperemized earlobe for lactate and pH measurement (and from an antecubital vein during test I), and the exercise intensities corresponding to the lactate threshold (LT), individual anaerobic threshold (IAT), and onset of blood lactate accumulation (OBLA) were determined. The test III was performed at predetermined work loads (50 W below OBLA, at OBLA, and 50 W above OBLA), with the same stage and rest interval durations of tests I and II. Muscle biopsies for lactate and pH determination were taken at rest and immediately after the completion of the three exercise intensities. Blood samples were drawn simultaneously with each biopsy. Muscle lactate concentrations increased abruptly at exercise intensities greater than the “below-OBLA” stage [50.5% maximal O2 uptake (VO2 max)] and resembled a threshold. An increase in blood lactate and [H+] also occurred at the below-OBLA stage; however, no significant change in muscle [H+] was observed. Muscle lactate concentrations were highly correlated to blood lactate (r = 0.91), and muscle-to-blood lactate ratios at below-OBLA, at-OBLA, and above-OBLA stages were 0.74, 0.63, 0.96, and 0.95, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

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