Validity of predictive equations for resting metabolic rate in healthy humans

2018 ◽  
Vol 132 (16) ◽  
pp. 1741-1751 ◽  
Author(s):  
Jose E. Galgani ◽  
Mauricio Castro-Sepulveda ◽  
Cristian Pérez-Luco ◽  
Rodrigo Fernández-Verdejo

Background: There are several predictive equations for estimating resting metabolic rate (RMR) in healthy humans. Concordance of these equations against measured RMR is variable, and often dependent on the extent of RMR. Part of the discrepancy may be due to an insufficient accuracy of metabolic carts, but this accuracy can be improved via a correction procedure. Objective: To determine the validity of predictive RMR equations by comparing them against measured and corrected (i.e. the reference) RMR. Methods: RMR was measured, in 69 healthy volunteers (29 males/40 females; 32±8 years old; BMI 25.5±3.8 kg/m2) and then corrected by simulating gas exchange through pure gases and high-precision mass-flow regulators. RMR was predicted using 13 published equations. Bland–Altman analyses compared predicted vs. reference RMRs. Results: All equations correlated well with the reference RMR (r>0.67; P<0.0001), but on average, over-predicted the reference RMR (89–312 kcal/d; P<0.05). Based on Bland–Altman analyses, 12 equations showed a constant bias across RMR, but the bias was not different from zero for nine of them. Three equations stood out because the absolute difference between predicted and reference RMR was equal or lower than 200 kcal/d for >60% of individuals (the Mifflin, Oxford and Müller equations). From them, only the Oxford equations performed better in both males and females separately. Conclusion: The Oxford equations are a valid alternative to predict RMR in healthy adult humans. Gas-exchange correction appears to be a good practice for the reliable assessment of RMR.

Nutrition ◽  
2009 ◽  
Vol 25 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Maria Skouroliakou ◽  
Ifigenia Giannopoulou ◽  
Christina Kostara ◽  
Melanie Vasilopoulou

2017 ◽  
Vol 22 ◽  
pp. 64-70 ◽  
Author(s):  
Aya Itoi ◽  
Yosuke Yamada ◽  
Keiichi Yokoyama ◽  
Tetsuji Adachi ◽  
Misaka Kimura

2017 ◽  
Vol 30 (5) ◽  
pp. 583-591 ◽  
Author(s):  
Randhall Bruce CARTERI ◽  
Marceli FELDMANN ◽  
Júlia Silveira GROSS ◽  
Renata Lopes KRUGER ◽  
André Luis LOPES ◽  
...  

ABSTRACT Objective To compare resting metabolic rate values determined by indirect calorimetry with values estimated using different predictive equations in lean and overweight postmenopausal women. Methods Twenty-four women, who had stopped menstruating for at least two years, were subjected to anthropometric measurements and indirect calorimetry after 12-hour overnight fasting to determine, mathematically and experimentally, resting metabolic rate values. Results There was no difference in the indirect calorimetry values between the groups evaluated. Difference values of resting metabolic rate were obtained with all equations used. For the lean women, there was no difference between the values obtained by indirect calorimetry and those estimated using the equations proposed by Food and Agricultural Organization, Fredix, Lazzer, and Schofield. However, in the overweight group, the resting metabolic rate values estimated using the Institute of Medicine, Berstein and Owen equations were different from those obtained by indirect calorimetry. Conclusion This study suggests that differences in body composition in postmenopausal women influence the accuracy of predictive equations, demonstrating the need for more accurate estimation methods for resting metabolic rate in postmenopausal women with different body compositions.


2012 ◽  
Vol 17 (3) ◽  
pp. 211-214 ◽  
Author(s):  
V. Bonganha ◽  
C. A. Libardi ◽  
C. F. Santos ◽  
G. V. De Souza ◽  
M. S. Conceiçaõ ◽  
...  

2017 ◽  
Vol 49 (5S) ◽  
pp. 579
Author(s):  
Lucas K. Shrum ◽  
Karl G. Keczkemethy ◽  
Jeremy T. Barnes ◽  
Thomas J. Pujol ◽  
Jason D. Wagganer

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