Serum leptin concentrations in patients with anorexia nervosa, bulimia nervosa and non-specific eating disorders correlate with the body mass index but are independent of the respective disease

1997 ◽  
Vol 46 (3) ◽  
pp. 289-293 ◽  
Author(s):  
Fernando Ferron ◽  
Robert V. Considine ◽  
Roberto Peino ◽  
Isabel G. Lado ◽  
Carlos Dieguez ◽  
...  
2021 ◽  
Vol 2 (1) ◽  
pp. 66-72
Author(s):  
Ana Luísa Arantes Pagano ◽  
◽  
Gabriela Bueno Araújo ◽  
Gabriela Spolon Freitas ◽  
Rafaela Garcia Lopes ◽  
...  

Introduction: The concept of body image is defined as the subjective image about the forms and characteristics of the body itself, which integrates physical, mental, and emotional levels about this perception. Excessive concern with weight and body shape and the divinization of exaggerated thinness can lead to eating disorders, which are characterized as psychiatric diseases defined by changes in eating behavior, which mainly affects women, being a source of physical and psychological damage. One of the most common disorders is anorexia nervosa (AN). Objective: To analyze the body perception and anorexic behavior of students at a medical school in the interior of São Paulo. Methods: This is an observational, qualitative study to assess the body perception and anorexic behavior of university students at a medical school in the city of Catanduva-SP. The sample consisted of 141 students. To assess the perception of body image, the Kakeshita silhouette scale, and a visual analog scale were used. For the evaluation of the subjective component of the body image, a virtual questionnaire was applied by Google Forms on the evaluated components. The assessment of nutritional status considered the classification of the body mass index and the EAT-26 test. For statistical analysis, the Wilcoxon non-parametric test was used. Results: The students had an average age of 21.34 years ± 2.2 and an average height of 1.64 meters. The average of the real Body Mass Index (BMI) was 22.08 Kg/m², the perception of BMI was 26.40 Kg/m² and the desired BMI was 22.93 Kg/m², the last two being different statistically from the first. As for EAT-26, 73 students obtained a score greater than or equal to 21, which is considered a risky behavior for the development of AN. Conclusion: Most students have an altered perception of their body image since the perception of BMI is higher than the real BMI. In addition, it was noted, from the positive EAT-26, the existence of a high-risk behavior index for anorexia nervosa in the women in the sample. Thus, it is necessary to investigate the causes of the divergence between reality and looking at oneself in order to prevent such changes from becoming eating disorders.


2014 ◽  
Vol 12 (2) ◽  
pp. 175-180 ◽  
Author(s):  
Beatriz Vale ◽  
Sara Brito ◽  
Lígia Paulos ◽  
Pascoal Moleiro

Objective To analyse the progression of body mass index in eating disorders and to determine the percentile for establishment and resolution of the disease.Methods A retrospective descriptive cross-sectional study. Review of clinical files of adolescents with eating disorders.Results Of the 62 female adolescents studied with eating disorders, 51 presented with eating disorder not otherwise specified, 10 anorexia nervosa, and 1 bulimia nervosa. Twenty-one of these adolescents had menstrual disorders; in that, 14 secondary amenorrhea and 7 menstrual irregularities (6 eating disorder not otherwise specified, and 1 bulimia nervosa). In average, in anorectic adolescents, the initial body mass index was in 75thpercentile; secondary amenorrhea was established 1 month after onset of the disease; minimum weight was 76.6% of ideal body mass index (at 4th percentile) at 10.2 months of disease; and resolution of amenorrhea occurred at 24 months, with average weight recovery of 93.4% of the ideal. In eating disorder not otherwise specified with menstrual disorder (n=10), the mean initial body mass index was at 85thpercentile; minimal weight was in average 97.7% of the ideal value (minimum body mass index was in 52nd percentile) at 14.9 months of disease; body mass index stabilization occured at 1.6 year of disease; and mean body mass index was in 73rd percentile. Considering eating disorder not otherwise specified with secondary amenorrhea (n=4); secondary amenorrhea occurred at 4 months, with resolution at 12 months of disease (mean 65th percentile body mass index).Conclusion One-third of the eating disorder group had menstrual disorder − two-thirds presented with amenorrhea. This study indicated that for the resolution of their menstrual disturbance the body mass index percentiles to be achieved by female adolescents with eating disorders was 25-50 in anorexia nervosa, and 50-75, in eating disorder not otherwise specified.


Author(s):  
Johannes Hebebrand ◽  
G�nther W. Himmelmann ◽  
Helmut Heseker ◽  
Helmut Sch�fer ◽  
Helmut Remschmidt

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Hakan Uzun ◽  
Ozan Bitik ◽  
Yahya Baltu ◽  
Çiğdem Sönmez ◽  
Ayşegül Öztürk Kaymak

Background.The reduction mammaplasty has been a well-executed and known procedure in which considerable amount of fatty tissue is removed from the body. The authors aimed to show the effects of the reduction mammaplasty on serum leptin levels and insulin resistance.Methods.42 obese female patients who had gigantomastia were operated on. We recorded patients’ demographic and preoperative data, including age, weight, height, and body mass index. Fasting serum leptin, glucose, and insulin levels were noted. Homeostasis model assessment scores were calculated. At the postoperative 8th week, patients were reevaluated in terms of above parameters assessing the presence of any difference.Results.Serum leptin levels were decreased postoperatively and the decrease was statistically significant. We were able to show a decrease in homeostasis model assessment score, which indicated an increase in insulin sensitivity, and this change was statistically significant. A significant correlation between body mass index and leptin change was found postoperatively.Conclusion.Reduction mammaplasty is not solely an aesthetic procedure but it decreases serum leptin levels and increases insulin sensitivity, which may help obese women to reduce their cardiovascular risk.


2021 ◽  
Vol 25 (2) ◽  
pp. 121-129
Author(s):  
Hye-Ryeon Park ◽  
Hyeon Ok Ju

Purpose: The purpose of this study was to verify the mediating effects of body dissatisfaction, selfesteem, and depression on the association between the body mass index (BMI) and eating disorders in adolescents with type 1 diabetes.Methods: Secondary data were analyzed in this study. The original analysis was conducted using data from 136 adolescents aged 13–18 years with type 1 diabetes. The results of testing for mediating effects were analyzed using a serial-multiple mediation model (model 6) using the PROCESS macro in SPSS ver. 3.3.Results: The direct effect of the BMI on eating disorders was not statistically significant (effect=0.22; 95 % confidence interval [CI], -0.20 to 0.64), but the indirect effects were statistically significant (effect=0.28; 95% CI, 0.05–0.63). In detail, the indirect effect of BMI on eating disorders mediated by body dissatisfaction was statistically significant (effect=0.28; 95% CI, 0.10–0.61); by body dissatisfaction and depression was statistically significant (effect=0.06; 95% CI, 0.01–0.15); and by body dissatisfaction, self-esteem, and depression was statistically significant (effect=0.05; 95% CI, 0.01–0.11).Conclusion: Individual interventions according to BMI are required to prevent the development of eating disorders in adolescents with type 1 diabetes. Adolescents with type 1 diabetes require intervention programs that may positively change their attitudes toward themselves, increasing self-esteem and lowering depression.


2017 ◽  
Vol 51 (6) ◽  
pp. 583-594 ◽  
Author(s):  
Katherine M Kirk ◽  
Felicity C Martin ◽  
Amy Mao ◽  
Richard Parker ◽  
Sarah Maguire ◽  
...  

Objectives: Anorexia nervosa is a severe psychiatric disorder with high mortality rates. While its aetiology is poorly understood, there is evidence of a significant genetic component. The Anorexia Nervosa Genetics Initiative is an international collaboration which aims to understand the genetic basis of the disorder. This paper describes the recruitment and characteristics of the Australasian Anorexia Nervosa Genetics Initiative sample, the largest sample of individuals with anorexia nervosa ever assembled across Australia and New Zealand. Methods: Participants completed an online questionnaire based on the Structured Clinical Interview Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV) eating disorders section. Participants who met specified case criteria for lifetime anorexia nervosa were requested to provide a DNA sample for genetic analysis. Results: Overall, the study recruited 3414 Australians and 543 New Zealanders meeting the lifetime anorexia nervosa case criteria by using a variety of conventional and social media recruitment methods. At the time of questionnaire completion, 28% had a body mass index ⩽ 18.5 kg/m2. Fasting and exercise were the most commonly employed methods of weight control, and were associated with the youngest reported ages of onset. At the time of the study, 32% of participants meeting lifetime anorexia nervosa case criteria were under the care of a medical practitioner; those with current body mass index < 18.5 kg/m2 were more likely to be currently receiving medical care (56%) than those with current body mass index ⩾ 18.5 kg/m2 (23%). Professional treatment for eating disorders was most likely to have been received from general practitioners (45% of study participants), dietitians (42%) and outpatient programmes (42%). Conclusions: This study was effective in assembling the largest community sample of people with lifetime anorexia nervosa in Australia and New Zealand to date. The proportion of people with anorexia nervosa currently receiving medical care, and the most common sources of treatment accessed, indicates the importance of training for general practitioners and dietitians in treating anorexia nervosa.


Author(s):  
Johannes Hebebrand ◽  
G�nther W. Himmelmann ◽  
Christoph Wewetzer ◽  
Cornelius Gutenbrunner ◽  
Helmut Heseker ◽  
...  

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