Metastatic breast cancer in pregnancy: first case of chemotherapy with docetaxel

2000 ◽  
Vol 9 (4) ◽  
pp. 235-237 ◽  
Author(s):  
M. De Santis ◽  
A. Lucchese ◽  
S. De Carolis ◽  
S. Ferrazzani ◽  
A. Caruso
Cancer ◽  
1992 ◽  
Vol 69 (2) ◽  
pp. 453-456 ◽  
Author(s):  
T. R. J. Evans ◽  
R. C. Stein ◽  
H. T. Ford ◽  
J. C. Gazet ◽  
G. V. Chamberlain ◽  
...  

2020 ◽  
Vol 13 (1) ◽  
pp. e224455 ◽  
Author(s):  
Louise Dunphy ◽  
Giovanni Salzano ◽  
Barbara Gerber ◽  
Jennifer Graystone

In 2003, Marx reported the first case of osteonecrosis of the jaw in 36 cases related to zoledronic acid or pamidronate. Painful bone exposure in the mandible or maxilla unresponsive to medical or surgical management was observed. In 2014, the American Association of Oral and Maxillofacial Surgeons proposed the term ‘medication-related osteonecrosis of the jaw’ (MRONJ). However, a non-exposed variant may also occur. MRONJ can lead to debilitating clinical sequelae with limited treatment options. We present the case of a 73-year-old woman with metastatic breast cancer and MRONJ of her mandible and maxilla following treatment with intravenous zoledronic acid and denosumab. Six months following dental extractions, she was referred to the Department of Oral and Maxillofacial Surgery for assessment of extensive necrosis of her maxilla and mandible. Extraoral draining sinuses were observed. A CT mandible showed cortical destruction with an ill-defined mixed sclerotic–lucent pattern in keeping with osteonecrosis. Due to her metastatic breast cancer, the extent of her necrosis and poor performance status, free flap reconstruction of her mandible was ruled out. She was treated conservatively.


2021 ◽  
pp. 1608-1615
Author(s):  
Ana S. Acostamadiedo Marx ◽  
Camilo Andrés Avendaño-Capriles ◽  
Julio A. Lemos ◽  
Eric Gorman ◽  
Jose M. Acostamadiedo

To our knowledge, this is the first case reported in the English literature of simultaneous occult male metastatic breast cancer presenting as pulmonary nodules and right axillary lymph node metastasis in a chronic lymphocytic leukemia (CLL) patient and is the second case of simultaneous male breast cancer and CLL reported. The first case was reported by Dubashi et al. [Curr Oncol. 2011;18(2):e101–2] in 2011. This unique clinical and pathological entity presents various challenges in its management, including early detection, screening, and treatment.


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