scholarly journals Effects of medium‐ and long‐chain triglycerides on sleep and thermoregulatory processes in neonates

1998 ◽  
Vol 7 (1) ◽  
pp. 31-39 ◽  
Author(s):  
FREDERIC TELLIEZ ◽  
VERONIQUE BACH ◽  
GERARD DEWASMES ◽  
ANDRE LEKE ◽  
JEAN‐PIERRE LIBERT
1996 ◽  
Vol 76 (03) ◽  
pp. 369-371 ◽  
Author(s):  
T A B Sanders ◽  
G J Miller ◽  
Tamara de Grassi ◽  
Najat Yahia

SummaryFactor VII coagulant activity (FVIIc) is associated with an increased risk of fatal ischaemic heart disease (IHD). Several reports have suggested that dietary fat intake or hypertriglyceridaemia are associated with elevated levels of FVII. This study demonstrates that an intake of long-chain fatty acids sufficient to induce postprandial lipaemia in healthy subjects leads to a substantial elevation in both FVIIc and the concentration of FVII circulating in the activated form. Such an increase in FVIIc could not be induced by medium-chain triglycerides. These results suggest that the consumption of a sufficient amount of long-chain triglycerides to induce postprandial lipaemia induces the activation of FVII.


1998 ◽  
Vol 274 (6) ◽  
pp. G1160-G1165
Author(s):  
M. Ledeboer ◽  
A. A. M. Masclee ◽  
I. Biemond ◽  
C. B. H. W. Lamers

Fat meals are known to decrease lower esophageal sphincter (LES) pressure, possibly through postprandial CCK release. Dietary fat consists mainly of long-chain triglycerides (LCT), which potently stimulate CCK secretion. This effect contrasts with that of medium-chain triglycerides (MCT), which do not induce CCK release. We recorded LES pressure and gallbladder volume in six healthy subjects on five separate occasions during intraduodenal administration of 1) saline control, 2) LCT, 3) MCT, 4) LCT during intravenous infusion of the CCK receptor antagonist loxiglumide, and 5) MCT together with loxiglumide. LES pressure decreased significantly during administration of both LCT and MCT. Loxiglumide completely prevented the reduction in LES pressure during intraduodenal LCT, but not during intraduodenal MCT. Gallbladder volume decreased during LCT, but not during MCT. It is concluded that intraduodenal administration of equimolar amounts of both LCT and MCT significantly reduces LES pressure. The effect of LCT on LES pressure is mediated by CCK. The effect of MCT is not dependent on CCK, since MCT does not release CCK and loxiglumide does not prevent the MCT-induced reduction in LES pressure.


2002 ◽  
Vol 80 (1) ◽  
pp. 38-44 ◽  
Author(s):  
L. Averette Gatlin ◽  
J. Odle ◽  
J. Soede ◽  
J. A. Hansent

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