Antimicrobial Susceptibilities of Erysipelothrix rhusiopathiae Isolated from Pigs with Swine Erysipelas in Japan, 1988-1998

2001 ◽  
Vol 48 (2) ◽  
pp. 115-126 ◽  
Author(s):  
K. Yamamoto ◽  
M. Kijima ◽  
H. Yoshimura ◽  
T. Takahashi
2017 ◽  
Vol 83 (11) ◽  
Author(s):  
Yohsuke Ogawa ◽  
Kazumasa Shiraiwa ◽  
Yoshitoshi Ogura ◽  
Tadasuke Ooka ◽  
Sayaka Nishikawa ◽  
...  

ABSTRACTErysipelothrix rhusiopathiaecauses swine erysipelas, an important infectious disease in the swine industry. In Japan, the incidence of acute swine erysipelas due toE. rhusiopathiaeserovar 1a has recently increased markedly. To study the genetic relatedness of the strains from the recent cases, we analyzed 34E. rhusiopathiaeserovar 1a swine isolates collected between 1990 and 2011 and further investigated the possible association of the live Koganei 65-0.15 vaccine strain (serovar 1a) with the increase in cases. Pulsed-field gel electrophoresis analysis revealed no marked variation among the isolates; however, sequencing analysis of a hypervariable region in the surface-protective antigen A gene (spaA) revealed that the strains isolated after 2007 exhibited the samespaAgenotype and could be differentiated from older strains. Phylogenetic analysis based on genome-wide single-nucleotide polymorphisms (SNPs) revealed that the Japanese strains examined were closely related, showing a relatively small number of SNPs among them. The strains were classified into four major lineages, with Koganei 65-0.15 (lineage III) being phylogenetically separated from the other three lineages. The strains isolated after 2007 and the two older strains constituted one major lineage (lineage IV) with a specificspaAgenotype (M203/I257-SpaA), while the recent isolates were further divided into two geographic groups. The remaining older isolates belonged to either lineage I, with the I203/L257-SpaA type, or lineage II, with the I203/I257-SpaA type. These results indicate that the recent increased incidence of acute swine erysipelas in Japan is associated with two sublineages of lineage IV, which have independently evolved in two different geographic regions.IMPORTANCEUsing large-scale whole-genome sequence data fromErysipelothrix rhusiopathiaeisolates from a wide range of hosts and geographic origins, a recent study clarified the existence of three distinct clades (clades 1, 2, and 3) that are found across multiple continents and host species, representing both livestock and wildlife, and an “intermediate” clade between clade 2 and the dominant clade 3 within the species. In this study, we found that theE. rhusiopathiaeJapanese strains examined exhibited remarkably low levels of genetic diversity and confirmed that all of the Japanese and Chinese swine isolates examined in this study belong to clonal lineages within the intermediate clade. We report thatspaAgenotyping ofE. rhusiopathiaestrains is a practical alternative to whole-genome sequencing analysis of theE. rhusiopathiaeisolates from eastern Asian countries.


Biologicals ◽  
2014 ◽  
Vol 42 (2) ◽  
pp. 109-113 ◽  
Author(s):  
Mariko Uchiyama ◽  
Kinya Yamamoto ◽  
Mariko Ochiai ◽  
Tsukasa Yamamoto ◽  
Fumiya Hirano ◽  
...  

2021 ◽  
pp. 1-7
Author(s):  
Dessalew Habte ◽  
◽  
Dessalew Tamir ◽  

Erysipelas is an infectious disease seen mainly in growing pigs and characterized clinically by fever, arthritis, skin lesions and sudden death. The disease may be acute, subacute, or chronic. Swine erysipelas is a disease caused by a specific micro organ Erysipelothrix rhusiopathiae whic h is a zoonotic ubiquitous gram-positive bacterium that causes erysipelas in swine, mammals, birds and erysipeloid in humans. People in contact with animals, animal products or animal wastes are at greatest risk. The acute form of swine erysipelas may have been confused for other diseases in pigs which are characterized by acute symptoms such as sudden death (for example, African swine fever). It can be diagnosed by its clinical signs, necropsy findings, bacteriology, antimicrobial response, molecular and serological examinations. It is recommended to increase awareness of the disease among animal and human practitioners as treatment is easy and available and vaccination is possible. However, the disease is still unknown to local veterinarians, clinical doctors, meat inspectors, butchers and laboratory personnel. Proper hygiene, regular pork inspection, use of protective wear among people working/ in contact with animals should be promoted. The disease causes high economic loss in pig rearing areas and influences the public health being a severe zoonotic disease. So the objective of this review is to create a better understanding of the disease for proper control and prevention of the disease


1990 ◽  
Vol 34 (10) ◽  
pp. 2038-2040 ◽  
Author(s):  
M Venditti ◽  
V Gelfusa ◽  
A Tarasi ◽  
C Brandimarte ◽  
P Serra

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