BENEFICIAL EFFECTS ON ALBUMINURIA IN EXPERIMENTAL DIABETES WITH ALT 946, A NOVEL INHIBITOR OF ADVANCED GLYCATION

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A99-A99
Author(s):  
Forbes Jm ◽  
Soulis T ◽  
Thallas V ◽  
Panagiotopoulos S ◽  
Jerums G.
Keyword(s):  
Experimental Diabetes ◽  
Advanced Glycation ◽  
Beneficial Effects

Beneficial effects on albuminuria in experimental diabetes with ALT 946, a novel inhibitor of advanced glycation

2000 ◽  
Vol 50 ◽  
pp. 356
Author(s):  
J.M Forbes ◽  
T Soulis ◽  
V Thallas ◽  
D Long ◽  
S Panagiotopoulos ◽  
...  
Keyword(s):  
Experimental Diabetes ◽  
Advanced Glycation ◽  
Beneficial Effects

Perinatal consumption of flaxseed oil and flaxseed flour has beneficial effects on cardiac fibrosis of male offspring from rat dams with experimental diabetes

2016 ◽  
Vol 83 ◽  
pp. 162-168 ◽  
Author(s):  
Gabriela Câmara Vicente ◽  
André Manoel Correia-Santos ◽  
Akemi Suzuki ◽  
Juliana Saraiva dos Anjos ◽  
Luis Guillermo Coca Velarde ◽  
...  
Keyword(s):  
Cardiac Fibrosis ◽  
Experimental Diabetes ◽  
Flaxseed Oil ◽  
Male Offspring ◽  
Beneficial Effects ◽  
Flaxseed Flour

EFFECT OF AMINOGUANIDINE ON CATARACTOGENESIS IN EXPERIMENTAL DIABETES MELLITUS

2019 ◽  
Vol 25 (5-6) ◽  
pp. 303-308
Author(s):  
A. A Spasov ◽  
Yulia A. Govorova ◽  
L. V Naumehko ◽  
D. A Babkov ◽  
A. S Taran ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Experimental Diabetes ◽  
Laboratory Animals ◽  
Cataract Formation ◽  
Advanced Glycation ◽  
Experimental Diabetes Mellitus ◽  
Nonenzymatic Glycosylation ◽  
Glycation End Products ◽  
End Products ◽  
Streptozotocin Induced Diabetes

Nonenzymatic glycosylation of lens proteins in diabetes mellitus is one of the pathogenetic mechanisms of cataract formation. According to the results of this study, aminoguanidine, which has anti-glycation activity, inhibits cataractogenesis in experimental diabetes. Laboratory animals with streptozotocin-induced diabetes mellitus treated with aminoguanidine showed less clouding in the lenses, and the content of advanced glycation end products, in particular, carboxymethyllysine, in the lenses was found to be reduced compared to the same parameters in animals from the control diabetic group.

The Role of Advanced Glycation in Reduced Organic Cation Transport Associated with Experimental Diabetes

2004 ◽  
Vol 311 (2) ◽  
pp. 456-466 ◽  
Author(s):  
Merlin C. Thomas ◽  
Christos Tikellis ◽  
Phillip Kantharidis ◽  
Wendy C. Burns ◽  
Mark E. Cooper ◽  
...  
Keyword(s):  
Organic Cation ◽  
Experimental Diabetes ◽  
Cation Transport ◽  
Organic Cation Transport ◽  
Advanced Glycation
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